Abcb11 (NM_021022) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR218267L4V

Lenti ORF particles, Abcb11 (GFP-tagged) - Mouse ATP-binding cassette, sub-family B (MDR/TAP), member 11 (Abcb11), 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Abcb11
• Synonyms: ABC1; ABC16; Bs; Bsep; Lit; Lith1; PFI; PFIC2; PGY; PGY4; SPGP
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR218267).
• ACCN: NM_021022
• ORF Size: 3963 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_021022.3, NP_066302.2
• RefSeq Size: 4899 bp
• RefSeq ORF: 3966 bp
• Locus ID: 27413
• UniProt ID: Q9QY30
• Cytogenetics: 2 39.69 cM
• Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt transporter in humans and mice. Mutations in the human gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]