Arhgap18 (NM_176837) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR209864L4V

Lenti ORF particles, Arhgap18 (GFP-tagged) - Mouse Rho GTPase activating protein 18 (Arhgap18), 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Arhgap18
• Synonyms: 4833419J07Rik; AI314906; AI843501
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR209864).
• ACCN: NM_176837
• ORF Size: 1989 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_176837.2, NP_789807.1
• RefSeq Size: 3616 bp
• RefSeq ORF: 1992 bp
• Locus ID: 73910
• UniProt ID: Q8K0Q5
• Cytogenetics: 10 A4
• Summary: Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state. Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1. Regulates cell shape, spreading, and migration (By similarity).[UniProtKB/Swiss-Prot Function]