Lox (NM_010728) Mouse Tagged ORF Clone Lentiviral Particle
SKU
MR206463L4V
Lenti ORF particles, Lox (GFP-tagged) - Mouse lysyl oxidase (Lox), 200ul, >10^7 TU/mL
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | Lox |
Synonyms | AI893619; rrg; TSC-16; TSC-160 |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(MR206463).
|
ACCN | NM_010728 |
ORF Size | 1233 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_010728.2 |
RefSeq Size | 3604 bp |
RefSeq ORF | 1236 bp |
Locus ID | 16948 |
UniProt ID | P28301 |
Cytogenetics | 18 28.22 cM |
Summary | This gene encodes a precursor protein that belongs to the lysyl oxidase family of proteins. The secreted proprotein is proteolytically processed to an active mature peptide and a propeptide. This propeptide is thought to function in tumor suppression by inhibiting the Ras signaling pathway. The active enzyme plays a role in cross-linking of collagen and elastin and is essential for development of cardiovascular and respiratory systems, and development of skin and connective tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013] |
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