Mgmt (NM_008598) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR202297L2V

Lenti ORF particles, Mgmt (GFP-tagged) - Mouse O-6-methylguanine-DNA methyltransferase (Mgmt), 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Mgmt
• Synonyms: Agat; AGT; AI267024
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR202297).
• ACCN: NM_008598
• ORF Size: 633 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_008598.2, NP_032624.1
• RefSeq Size: 857 bp
• RefSeq ORF: 636 bp
• Locus ID: 17314
• UniProt ID: P26187
• Cytogenetics: 7 82.07 cM
• Summary: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.[UniProtKB/Swiss-Prot Function]