DPP9 (NM_139159) Human Untagged Clone

CAT#: SC328023

DPP9 (untagged)-Human dipeptidyl-peptidase 9 (DPP9)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DPP9
• Synonyms: DP9; DPLP9; DPP IX; DPRP-2; DPRP2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >SC328023 representing NM_139159.
  Blue=Insert sequence Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGCGGAAGGTTAAGAAACTGCGCCTGGACAAGGAGAACACCGGAAGTTGGAGAAGCTTCTCGCTGAAT
  TCCGAGGGGGCTGAGAGGATGGCCACCACCGGGACCCCAACGGCCGACCGAGGCGACGCAGCCGCCACA
  GATGACCCGGCCGCCCGCTTCCAGGTGCAGAAGCACTCGTGGGACGGGCTCCGGAGCATCATCCACGGC
  AGCCGCAAGTACTCGGGCCTCATTGTCAACAAGGCGCCCCACGACTTCCAGTTTGTGCAGAAGACGGAT
  GAGTCTGGGCCCCACTCCCACCGCCTCTACTACCTGGGAATGCCATATGGCAGCCGAGAGAACTCCCTC
  CTCTACTCTGAGATTCCCAAGAAGGTCCGGAAAGAGGCTCTGCTGCTCCTGTCCTGGAAGCAGATGCTG
  GATCATTTCCAGGCCACGCCCCACCATGGGGTCTACTCTCGGGAGGAGGAGCTGCTGAGGGAGCGGAAA
  CGCCTGGGGGTCTTCGGCATCACCTCCTACGACTTCCACAGCGAGAGTGGCCTCTTCCTCTTCCAGGCC
  AGCAACAGCCTCTTCCACTGCCGCGACGGCGGCAAGAACGGCTTCATGGTGTCCCCTATGAAACCGCTG
  GAAATCAAGACCCAGTGCTCAGGGCCCCGGATGGACCCCAAAATCTGCCCTGCCGACCCTGCCTTCTTC
  TCCTTCATCAATAACAGCGACCTGTGGGTGGCCAACATCGAGACAGGCGAGGAGCGGCGGCTGACCTTC
  TGCCACCAAGGTTTATCCAATGTCCTGGATGACCCCAAGTCTGCGGGTGTGGCCACCTTCGTCATACAG
  GAAGAGTTCGACCGCTTCACTGGGTACTGGTGGTGCCCCACAGCCTCCTGGGAAGGTTCAGAGGGCCTC
  AAGACGCTGCGAATCCTGTATGAGGAAGTCGATGAGTCCGAGGTGGAGGTCATTCACGTCCCCTCTCCT
  GCGCTAGAAGAAAGGAAGACGGACTCGTATCGGTACCCCAGGACAGGCAGCAAGAATCCCAAGATTGCC
  TTGAAACTGGCTGAGTTCCAGACTGACAGCCAGGGCAAGATCGTCTCGACCCAGGAGAAGGAGCTGGTG
  CAGCCCTTCAGCTCGCTGTTCCCGAAGGTGGAGTACATCGCCAGGGCCGGGTGGACCCGGGATGGCAAA
  TACGCCTGGGCCATGTTCCTGGACCGGCCCCAGCAGTGGCTCCAGCTCGTCCTCCTCCCCCCGGCCCTG
  TTCATCCCGAGCACAGAGAATGAGGAGCAGCGGCTAGCCTCTGCCAGAGCTGTCCCCAGGAATGTCCAG
  CCGTATGTGGTGTACGAGGAGGTCACCAACGTCTGGATCAATGTTCATGACATCTTCTATCCCTTCCCC
  CAATCAGAGGGAGAGGACGAGCTCTGCTTTCTCCGCGCCAATGAATGCAAGACCGGCTTCTGCCATTTG
  TACAAAGTCACCGCCGTTTTAAAATCCCAGGGCTACGATTGGAGTGAGCCCTTCAGCCCCGGGGAAGAT
  GAATTTAAGTGCCCCATTAAGGAAGAGATTGCTCTGACCAGCGGTGAATGGGAGGTTTTGGCGAGGCAC
  GGCTCCAAGATCTGGGTCAATGAGGAGACCAAGCTGGTGTACTTCCAGGGCACCAAGGACACGCCGCTG
  GAGCACCACCTCTACGTGGTCAGCTATGAGGCGGCCGGCGAGATCGTACGCCTCACCACGCCCGGCTTC
  TCCCATAGCTGCTCCATGAGCCAGAACTTCGACATGTTCGTCAGCCACTACAGCAGCGTGAGCACGCCG
  CCCTGCGTGCACGTCTACAAGCTGAGCGGCCCCGACGACGACCCCCTGCACAAGCAGCCCCGCTTCTGG
  GCTAGCATGATGGAGGCAGCCAGCTGCCCCCCGGATTATGTTCCTCCAGAGATCTTCCATTTCCACACG
  CGCTCGGATGTGCGGCTCTACGGCATGATCTACAAGCCCCACGCCTTGCAGCCAGGGAAGAAGCACCCC
  ACCGTCCTCTTTGTATATGGAGGCCCCCAGGTGCAGCTGGTGAATAACTCCTTCAAAGGCATCAAGTAC
  TTGCGGCTCAACACACTGGCCTCCCTGGGCTACGCCGTGGTTGTGATTGACGGCAGGGGCTCCTGTCAG
  CGAGGGCTTCGGTTCGAAGGGGCCCTGAAAAACCAAATGGGCCAGGTGGAGATCGAGGACCAGGTGGAG
  GGCCTGCAGTTCGTGGCCGAGAAGTATGGCTTCATCGACCTGAGCCGAGTTGCCATCCATGGCTGGTCC
  TACGGGGGCTTCCTCTCGCTCATGGGGCTAATCCACAAGCCCCAGGTGTTCAAGGTGGCCATCGCGGGT
  GCCCCGGTCACCGTCTGGATGGCCTACGACACAGGGTACACTGAGCGCTACATGGACGTCCCTGAGAAC
  AACCAGCACGGCTATGAGGCGGGTTCCGTGGCCCTGCACGTGGAGAAGCTGCCCAATGAGCCCAACCGC
  TTGCTTATCCTCCACGGCTTCCTGGACGAAAACGTGCACTTTTTCCACACAAACTTCCTCGTCTCCCAA
  CTGATCCGAGCAGGGAAACCTTACCAGCTCCAGATCTACCCCAACGAGAGACACAGTATTCGCTGCCCC
  GAGTCGGGCGAGCACTATGAAGTCACGTTGCTGCACTTTCTACAGGAATACCTCTGA
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
  TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_139159
• Insert Size: 2679 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_139159.3
• RefSeq Size: 4286 bp
• RefSeq ORF: 2679 bp
• Locus ID: 91039
• UniProt ID: Q86TI2
• Cytogenetics: 19p13.3
• Domains: Peptidase_S9, DPPIV_N_term
• Protein Families: Druggable Genome, Protease
• MW: 101.7 kDa
• Gene Summary: This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Although the activity of this protein is similar to that of dipeptidyl peptidase 4 (DPP4), it does not appear to be membrane bound. In general, dipeptidyl peptidases appear to be involved in the regulation of the activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. Several transcript variants of this gene have been described but not fully characterized. [provided by RefSeq, Jul 2008]