NPAS3 (NM_001164749) Human Untagged Clone

SKU SC327254

NPAS3 (untagged)-Human neuronal PAS domain protein 3 (NPAS3) transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: NPAS3
• Synonyms: bHLHe12; MOP6; PASD6
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_001164749 edited; ATGGCGCCCACCAAGCCCAGCTTTCAGCAGGATCCTTCCAGGCGAGAACGAATAACTGCC; CAGCATCCTCTGCCCAACCAATCAGAATGTAGGAAAATCTACAGATATGACGGAATCTAC; TGTGAATCTACCTACCAGAATTTACAAGCATTGAGAAAGGAGAAATCCCGAGATGCTGCT; CGCTCCCGCCGGGGAAAAGAAAACTTTGAGTTCTATGAATTGGCCAAGTTGTTGCCTCTT; CCTGCAGCCATTACCAGCCAGCTCGACAAGGCATCCATCATTCGACTTACAATTAGCTAT; CTGAAAATGAGGGACTTTGCTAACCAGGGGGACCCTCCGTGGAACTTGCGAATGGAAGGC; CCTCCACCTAACACATCAGTAAAAGTTATAGGTGCACAGCGAAGGAGAAGCCCCAGTGCA; CTAGCCATTGAAGTATTTGAAGCACATTTGGGAAGCCACATTTTGCAGTCCCTGGATGGC; TTTGTATTTGCACTAAATCAGGAAGGAAAATTTTTGTACATTTCCGAAACAGTCTCCATC; TACCTAGGCCTCTCACAAGTGGAGCTGACAGGCAGCAGTGTCTTTGACTATGTCCACCCC; GGAGATCACGTGGAGATGGCTGAGCAGCTGGGCATGAAGCTCCCCCCTGGGCGGGGTCTC; CTGTCACAGGGCACTGCTGAGGACGGAGCCAGCTCAGCATCTTCCTCCTCTCAGTCGGAG; ACCCCCGAGCCAGTGGAGTCAACCAGCCCCAGTCTGCTAACCACTGACAACACTCTTGAG; CGTTCCTTTTTCATCCGAATGAAATCTACTCTGACCAAACGCGGTGTGCACATCAAATCA; TCAGGATATAAGGTGATTCACATAACAGGCCGGCTACGCCTGAGAGTGTCGCTGTCCCAC; GGGAGGACCGTCCCCAGCCAAATCATGGGTCTCGTGGTTGTTGCGCATGCCTTGCCTCCC; CCTACGATCAATGAAGTCAGAATTGACTGCCATATGTTCGTCACTCGAGTAAATATGGAC; CTCAATATCATTTACTGTGAAAATAGGATTAGTGATTATATGGATCTGACCCCTGTAGAT; ATCGTAGGGAAGAGATGCTACCACTTCATCCATGCTGAAGACGTGGAGGGCATCAGGCAC; AGTCACTTGGACTTGCTGAATAAGGGTCAGTGTGTGACAAAGTACTATCGCTGGATGCAG; AAGAACGGAGGATATATTTGGATACAGTCCAGTGCCACCATAGCTATTAATGCCAAGAAT; GCAAATGAAAAGAATATCATCTGGGTGAATTACCTTCTTAGCAATCCTGAGTACAAGGAC; ACACCCATGGACATCGCACAGCTCCCCCATCTGCCGGAGAAAACTTCCGAATCCTCGGAG; ACATCCGACTCTGAGTCAGACTCTAAAGACACCTCAGGTATTACAGAGGACAACGAGAAC; TCCAAGTCCGACGAGAAGGGGAACCAGTCCGAGAACAGCGAAGACCCGGAGCCCGACCGG; AAGAAGTCGGGCAACGCGTGTGACAACGACATGAACTGCAACGACGACGGCCACAGCTCC; AGTAACCCGGACAGCCGCGACAGCGACGACAGCTTCGAGCACTCGGACTTTGAGAACCCC; AAGGCGGGCGAGGACGGCTTCGGTGCTCTGGGCGCGATGCAGATCAAGGTGGAGCGCTAC; GTGGAGAGCGAGTCGGACCTGCGGCTGCAGAACTGCGAGTCACTCACGTCCGACAGCGCC; AAGGACTCGGACAGCGCAGGCGAGGCGGGCGCGCAGGCCTCCAGCAAGCACCAGAAGCGC; AAGAAAAGGCGGAAACGGCAAAAGGGCGGCAGCGCCAGCCGCCGGCGCCTGTCCAGCGCG; TCGAGCCCAGGCGGCCTGGACGCGGGCCTGGTGGAGCCCCCGCGGCTGCTGTCCTCCCCC; AACAGTGCCTCGGTGCTCAAGATCAAGACGGAGATCTCAGAACCCATCAATTTCGACAAT; GACAGCAGCATCTGGAACTACCCGCCCAACCGGGAGATCTCCAGGAACGAGTCCCCCTAC; AGCATGACCAAGCCCCCCAGCTCTGAGCACTTCCCGTCCCCGCAGGGCGGCGGCGGTGGG; GGTGGCGGTGGCGGGGGGCTGCACGTGGCCATTCCCGACTCGGTCCTCACCCCGCCCGGC; GCCGACGGCGCGGCCGCCCGCAAGACTCAGTTCGGCGCCTCGGCCACCGCGGCCCTGGCC; CCCGTCGCCTCCGACCCGCTGTCACCCCCGCTCTCGGCGTCCCCGCGGGACAAGCACCCC; GGGAACGGCGGCGGGGGCGGGGGCGGGGGCGGCGGCGCGGGGGGCGGCGGCCCCAGCGCG; TCCAACTCCTTGCTGTACACTGGGGACCTGGAGGCGCTGCAGAGGTTGCAGGCGGGCAAC; GTCGTGCTCCCGCTGGTGCACAGGGTGACCGGGACCCTGGCCGCCACCAGCACGGCCGCG; CAGAGGGTCTACACCACGGGCACCATCCGCTACGCGCCCGCCGAGGTGACCCTGGCCATG; CAGAGCAACCTGCTGCCCAACGCGCACGCTGTTAACTTCGTGGACGTTAACAGCCCCGGC; TTTGGCCTCGACCCCAAGACGCCCATGGAGATGCTCTACCACCACGTGCACCGGCTCAAC; ATGTCAGGACCGTTCGGCGGCGCAGTGAGCGCAGCTAGCCTGACGCAGATGCCCGCCGGC; AACGTGTTCACCACGGCCGAGGGACTCTTCTCCACGCTGCCCTTCCCCGTCTACAGCAAC; GGCATCCACGCGGCACAGACTCTGGAGCGCAAGGAGGACTGA;
• Restriction Sites: Please inquire
• ACCN: NM_001164749
• Insert Size: 2800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001164749.1.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001164749.1, NP_001158221.1
• RefSeq Size: 5939 bp
• RefSeq ORF: 2802 bp
• Locus ID: 64067
• UniProt ID: Q8IXF0
• Cytogenetics: 14q13.1
• Protein Families: Druggable Genome
• Summary: This gene encodes a member of the basic helix-loop-helix and PAS domain-containing family of transcription factors. The encoded protein is localized to the nucleus and may regulate genes involved in neurogenesis. Chromosomal abnormalities that affect the coding potential of this gene are associated with schizophrenia and cognitive disability. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]; Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.