ZNF259 (ZPR1) (NM_003904) Human Untagged Clone

CAT#: SC324610

ZNF259 (untagged)-Human zinc finger protein 259 (ZNF259)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZNF259
• Synonyms: GKAF; ZNF259
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003904.3 AGGAAGCCGAGGTCTGAATTGCGCGTGGTGGCCATGGCGGCCAGCGGGGCTGTGGAACCA
  GGGCCCCCGGGGGCTGCCGTCGCCCCGTCGCCCGCCCCGGCCCCGCCGCCTGCCCCTGAT
  CACCTGTTCCGGCCCATCAGCGCCGAGGACGAGGAGCAGCAGCCCACCGAGATCGAGTCG
  CTATGCATGAACTGTTACTGCAATGGCATGACGCGCCTCCTGCTCACCAAGATTCCCTTC
  TTCAGAGAAATAATAGTGAGCTCCTTTTCCTGCGAGCACTGTGGCTGGAACAACACGGAG
  ATCCAGTCGGCAGGCAGGATCCAGGACCAGGGAGTGCGCTACACTTTGTCTGTCAGGGCT
  CTGGAGGACATGAACAGAGAAGTGGTGAAGACTGACTCTGCTGCCACAAGGATTCCTGAG
  CTAGATTTTGAAATTCCTGCCTTTAGCCAGAAAGGAGCTCTGACCACTGTTGAAGGATTG
  ATCACCCGTGCTATCTCTGGCCTGGAGCAGGACCAGCCTGCACGAAGGGCAAACAAAGAT
  GCTACAGCTGAAAGAATTGATGAGTTCATTGTCAAACTGAAGGAGCTAAAGCAAGTAGCC
  TCCCCTTTCACTCTGATCATTGATGATCCCTCAGGGAACAGTTTTGTGGAAAACCCACAT
  GCTCCTCAGAAAGATGATGCCCTGGTGATCACACACTACAACCGGACCCGACAGCAGGAA
  GAGATGCTGGGGCTTCAAGAAGAAGCACCAGCAGAGAAGCCAGAAGAGGAAGATCTCAGA
  AATGAAGTGCTCCAGTTCAGCACAAACTGCCCAGAATGCAATGCCCCCGCTCAGACCAAC
  ATGAAGCTAGTACAAATCCCTCACTTTAAGGAGGTTATCATCATGGCTACCAACTGCGAG
  AACTGTGGGCATCGGACCAATGAGGTGAAATCTGGAGGAGCAGTAGAACCCTTGGGCACC
  AGGATCACCCTCCACATCACAGATGCCTCAGATATGACCAGAGACCTCCTCAAGTCTGAG
  ACTTGCAGTGTGGAAATCCCAGAGCTAGAATTTGAACTGGGAATGGCAGTCCTCGGGGGC
  AAGTTCACCACACTGGAAGGGCTGCTGAAAGACATCCGGGAACTGGTGACCAAAAATCCT
  TTCACACTGGGCGACAGTTCCAATCCTGGACAGACGGAGAGACTACAGGAGTTTAGCCAG
  AAGATGGACCAGATCATCGAAGGTAACATGAAGGCCCACTTTATTATGGATGATCCAGCA
  GGAAACAGTTACTTGCAGAATGTGTATGCGCCTGAAGATGATCCTGAGATGAAGGTGGAG
  CGTTACAAGCGCACCTTTGACCAAAATGAGGAGCTAGGGCTCAATGACATGAAGACAGAG
  GGCTATGAGGCAGGCCTGGCTCCGCAACGGTAGCAGTGGGTGGCTCAAGGGCCAGCCTCC
  AGCGCTGCTCTTTCTGTAGGTTATTTATTAGTATTGGATGAAGGCGAAGGCTGGGAGTGT
  CTTTCCCACCAGCCCTTGCCCATGGTGGGGAGGACATCTGGTCTGAGTCAGAGATCTGTG
  CACACTTTCTAAACAGCTTGTGATGCAAGTGTGAGCCTATTGTGTTACTTGACCTTATTT
  TGGAAGTTTTGAATTGGCCTAGGAGGAAACCCAGAAATGAACCAGGGGTATGTCATCACT
  TTTTTCATATCAAGTCCTCACCCTCCTTCCACATAATGCTCTATCCTCTAAGGTTGGAAC
  TCTGAAGTTGGAGAAGGTGGAATAAAGTTACACCTGGAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_003904
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003904.3, NP_003895.1
• RefSeq Size: 1810 bp
• RefSeq ORF: 1380 bp
• Locus ID: 8882
• UniProt ID: O75312
• Cytogenetics: 11q23.3
• Domains: Zpr1
• Gene Summary: The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).