IGF2BP2 (NM_006548) Human Untagged Clone

CAT#: SC324486

IGF2BP2 (untagged)-Human insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IGF2BP2
• Synonyms: IMP-2; IMP2; VICKZ2
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006548.4 CGGAGGAGGCGAGGAGCGCCGGGTACCGGGCCGGGGGAGCCGCGGGCTCTCGGGGAAGAG
  ACGGATGATGAACAAGCTTTACATCGGGAACCTGAGCCCCGCCGTCACCGCCGACGACCT
  CCGGCAGCTCTTTGGGGACAGGAAGCTGCCCCTGGCGGGACAGGTCCTGCTGAAGTCCGG
  CTACGCCTTCGTGGACTACCCCGACCAGAACTGGGCCATCCGCGCCATCGAGACCCTCTC
  GGGTAAAGTGGAATTGCATGGGAAAATCATGGAAGTTGATTACTCAGTCTCTAAAAAGCT
  AAGGAGCAGGAAAATTCAGATTCGAAACATCCCTCCTCACCTGCAGTGGGAGGTGTTGGA
  TGGACTTTTGGCTCAATATGGGACAGTGGAGAATGTGGAACAAGTCAACACAGACACAGA
  AACCGCCGTTGTCAACGTCACATATGCAACAAGAGAAGAAGCAAAAATAGCCATGGAGAA
  GCTAAGCGGGCATCAGTTTGAGAACTACTCCTTCAAGATTTCCTACATCCCGGATGAAGA
  GGTGAGCTCCCCTTCGCCCCCTCAGCGAGCCCAGCGTGGGGACCACTCTTCCCGGGAGCA
  AGGCCACGCCCCTGGGGGCACTTCTCAGGCCAGACAGATTGATTTCCCGCTGCGGATCCT
  GGTCCCCACCCAGTTTGTTGGTGCCATCATCGGAAAGGAGGGCTTGACCATAAAGAACAT
  CACTAAGCAGACCCAGTCCCGGGTAGATATCCATAGAAAAGAGAACTCTGGAGCTGCAGA
  GAAGCCTGTCACCATCCATGCCACCCCAGAGGGGACTTCTGAAGCATGCCGCATGATTCT
  TGAAATCATGCAGAAAGAGGCAGATGAGACCAAACTAGCCGAAGAGATTCCTCTGAAAAT
  CTTGGCACACAATGGCTTGGTTGGAAGACTGATTGGAAAAGAAGGCAGAAATTTGAAGAA
  AATTGAACATGAAACAGGGACCAAGATAACAATCTCATCTTTGCAGGATTTGAGCATATA
  CAACCCGGAAAGAACCATCACTGTGAAGGGCACAGTTGAGGCCTGTGCCAGTGCTGAGAT
  AGAGATTATGAAGAAGCTGCGTGAGGCCTTTGAAAATGATATGCTGGCTGTTAACCAACA
  AGCCAATCTGATCCCAGGGTTGAACCTCAGCGCACTTGGCATCTTTTCAACAGGACTGTC
  CGTGCTATCTCCACCAGCAGGGCCCCGCGGAGCTCCCCCCGCTGCCCCCTACCACCCCTT
  CACTACCCACTCCGGATACTTCTCCAGCCTGTACCCCCATCACCAGTTTGGCCCGTTCCC
  GCATCATCACTCTTATCCAGAGCAGGAGATTGTGAATCTCTTCATCCCAACCCAGGCTGT
  GGGCGCCATCATCGGGAAGAAGGGGGCACACATCAAACAGCTGGCGAGATTCGCCGGAGC
  CTCTATCAAGATTGCCCCTGCGGAAGGCCCAGACGTCAGCGAAAGGATGGTCATCATCAC
  CGGGCCACCGGAAGCCCAGTTCAAGGCCCAGGGACGGATCTTTGGGAAACTGAAAGAGGA
  AAACTTCTTTAACCCCAAAGAAGAAGTGAAGCTGGAAGCGCATATCAGAGTGCCCTCTTC
  CACAGCTGGCCGGGTGATTGGCAAAGGTGGCAAGACCGTGAACGAACTGCAGAACTTAAC
  CAGTGCAGAAGTCATCGTGCCTCGTGACCAAACGCCAGATGAAAATGAGGAAGTGATCGT
  CAGAATTATCGGGCACTTCTTTGCTAGCCAGACTGCACAGCGCAAGATCAGGGAAATTGT
  ACAACAGGTGAAGCAGCAGGAGCAGAAATACCCTCAGGGAGTCGCCTCACAGCGCAGCAA
  GTGAGGCTCCCACAGGCACCAGCAAAACAACGGATGAATGTAGCCCTTCCAACACCTGAC
  AGAATGAGACCAAACGCAGCCAGCCAGATCGGGAGCAAACCAAAGACCATCTGAGGAATG
  AGAAGTCTGCGGAGGCGGCCAGGGACTCTGCCGAGGCCCTGAGAACCCCAGGGGCCGAGG
  AGGGGCGGGGAAGGTCAGCCAGGTTTGCCAGAACCACCGAGCCCCGCCTCCCGCCCCCCA
  GGGCTTCTGCAGGCTTCAGCCATCCACTTCACCATCCACTCGGATCTCTCCTGAACTCCC
  ACGACGCTATCCCTTTTAGTTGAACTAACATAGGTGAACGTGTTCAAAGCCAAGCAAAAT
  GCACACCCTTTTTCTGTGGCAAATCGTCTCTGTACATGTGTGTACATATTAGAAAGGGAA
  GATGTTAAGATATGTGGCCTGTGGGTTACACAGGGTGCCTGCAGCGGTAATATATTTTAG
  AAATAATATATCAAATAACTCAACTAACTCCAATTTTTAATCAATTATTAATTTTTTTTT
  CTTTTTAAAGAGAAAGCAGGCTTTTCTAGACTTTAAAGAATAAAGTCTTTGGGAGGTCTC
  ACGGTGTAGAGAGGAGCTTTGAGGCCACCCGCACAAAATTCACCCAGAGGGAAATCTCGT
  CGGAAGGACACTCACGGCAGTTCTGGATCACCTGTGTATGTCAACAGAAGGGATACCGTC
  TCCTTGAAGAGGAAACTCTGTCACTCCTCATGCCTGTCTAGCTCATACACCCATTTCTCT
  TTGCTTCACAGGTTTTAAACTGGTTTTTTGCATACTGCTATATAATTCTCTGTCTCTCTC
  TGTTTATCTCTCCCCTCCCTCCCCTCCCCTTCTTCTCCATCTCCATTCTTTTGAATTTCC
  TCATCCCTCCATCTCAATCCCGTATCTACGCACCCCCCCCCCCCAGGCAAAGCAGTGCTC
  TGAGTATCACATCACACAAAAGGAACAAAAGCGAAACACACAAACCAGCCTCAACTTACA
  CTTGGTTACTCAAAAGAACAAGAGTCAATGGTACTTGTCCTAGCGTTTTGGAAGAGGAAA
  ACAGGAACCCACCAAACCAACCAATCAACCAAACAAAGAAAAAATTCCACAATGAAAGAA
  TGTATTTTGTCTTTTTGCATTTTGGTGTATAAGCCATCAATATTCAGCAAAATGATTCCT
  TTCTTTAAAAAAAAAAAATGTGGAGGAAAGTAGAAATTTACCAAGGTTGTTGGCCCAGGG
  CGTTAAATTCACAGATTTTTTTAACGAGAAAAACACACAGAAGAAGCTACCTCAGGTGTT
  TTTACCTCAGCACCTTGCTCTTGTGTTTCCCTTAGAGATTTTGTAAAGCTGATAGTTGGA
  GCATTTTTTTATTTTTTTAATAAAAATGAGTTGGAAAAAAAATAAGATATCAACTGCCAG
  CCTGGAGAAGGTGACAGTCCAAGTGTGCAACAGCTGTTCTGAATTGTCTTCCGCTAGCCA
  AGAACCTATATGGCCTTCTTTTGGACAAACCTTGAAAATGTTTATTTAAAAAAAAAAAAG
  ATGACAAAGAAAAACAGAGAGAGAGAATATTGGAGATGTCCTGAATTTTAATAGGGTACG
  CGCCATTAGGGCTTTTTGCGCTAAAGGATGAACATGTACTGGTTTATGTGGACAAGCCAT
  TATACCACCAGACTGCAATGCCAGTTTCCTCTACTGCAAACAGTGTTCTGTGACAAAAAA
  AAAAAAAAAAAAAAGAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_006548
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006548.4, NP_006539.3
• RefSeq Size: 3676 bp
• RefSeq ORF: 1800 bp
• Locus ID: 10644
• UniProt ID: Q9Y6M1
• Cytogenetics: 3q27.2
• Domains: RRM, KH
• Gene Summary: This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016]