ICAM3 (NM_002162) Human Untagged Clone

CAT#: SC324335

ICAM3 (untagged)-Human intercellular adhesion molecule 3 (ICAM3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ICAM3
• Synonyms: CD50; CDW50; ICAM-R
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002162.2 GTCAGAATGGCCACCATGGTACCATCCGTGTTGTGGCCCAGGGCCTGCTGGACTCTGCTG
  GTCTGCTGTCTGCTGACCCCAGGTGTCCAGGGGCAGGAGTTCCTTTTGCGGGTGGAGCCC
  CAGAACCCTGTGCTCTCTGCTGGAGGGTCCCTGTTTGTGAACTGCAGTACTGATTGTCCC
  AGCTCTGAGAAAATCGCCTTGGAGACGTCCCTATCAAAGGAGCTGGTGGCCAGTGGCATG
  GGCTGGGCAGCCTTCAATCTCAGCAACGTGACTGGCAACAGTCGGATCCTCTGCTCAGTG
  TACTGCAATGGCTCCCAGATAACAGGCTCCTCTAACATCACCGTGTACAGGCTCCCGGAG
  CGTGTGGAGCTGGCACCCCTGCCTCCTTGGCAGCCGGTGGGCCAGAACTTCACCCTGCGC
  TGCCAAGTGGAGGATGGGTCGCCCCGGACCAGCCTCACGGTGGTGCTGCTTCGCTGGGAG
  GAGGAGCTGAGCCGGCAGCCCGCAGTGGAGGAGCCAGCGGAGGTCACTGCCACTGTGCTG
  GCCAGCAGAGACGACCACGGAGCCCCTTTCTCATGCCGCACAGAACTGGACATGCAGCCC
  CAGGGGCTGGGACTGTTCGTGAACACCTCAGCCCCCCGCCAGCTCCGAACCTTTGTCCTG
  CCCGTGACCCCCCCGCGCCTCGTGGCCCCCCGGTTCTTGGAGGTGGAAACGTCGTGGCCG
  GTGGACTGCACCCTAGACGGGCTTTTTCCAGCCTCAGAGGCCCAGGTCTACCTGGCGCTG
  GGGGACCAGATGCTGAATGCGACAGTCATGAACCACGGGGACACGCTAACGGCCACAGCC
  ACAGCCACGGCGCGCGCGGATCAGGAGGGTGCCCGGGAGATCGTCTGCAACGTGACCCTA
  GGGGGCGAGAGACGGGAGGCCCGGGAGAACTTGACGGTCTTTAGCTTCCTAGGACCCATT
  GTGAACCTCAGCGAGCCCACCGCCCATGAGGGGTCCACAGTGACCGTGAGTTGCATGGCT
  GGGGCTCGAGTCCAGGTCACGCTGGACGGAGTTCCGGCCGCGGCCCCGGGGCAGCCAGCT
  CAACTTCAGCTAAATGCTACCGAGAGTGACGACGGACGCAGCTTCTTCTGCAGTGCCACT
  CTCGAGGTGGACGGCGAGTTCTTGCACAGGAACAGTAGCGTCCAGCTGCGAGTCCTGTAT
  GGTCCCAAAATTGACCGAGCCACATGCCCCCAGCACTTGAAATGGAAAGATAAAACGAGA
  CACGTCCTGCAGTGCCAAGCCAGGGGCAACCCGTACCCCGAGCTGCGGTGTTTGAAGGAA
  GGCTCCAGCCGGGAGGTGCCGGTGGGGATCCCGTTCTTCGTCAACGTAACACATAATGGT
  ACTTATCAGTGCCAAGCGTCCAGCTCACGAGGCAAATACACCCTGGTCGTGGTGATGGAC
  ATTGAGGCTGGGAGCTCCCACTTTGTCCCCGTCTTCGTGGCGGTGTTACTGACCCTGGGC
  GTGGTGACTATCGTACTGGCCTTAATGTACGTCTTCAGGGAGCACCAACGGAGCGGCAGT
  TACCATGTTAGGGAGGAGAGCACCTATCTGCCCCTCACGTCTATGCAGCCGACAGAAGCA
  ATGGGGGAAGAACCGTCCAGAGCTGAGTGACGCTGGGATCCGGGATCAAAGTTGGCGGGG
  GCTTGGCTGTGCCCTCAGATTCCGCACCAATAAAGCCTTCAAACTCCCTAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_002162
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002162.2, NP_002153.1
• RefSeq Size: 1824 bp
• RefSeq ORF: 1644 bp
• Locus ID: 3385
• UniProt ID: P32942
• Cytogenetics: 19p13.2
• Domains: ig, IG, ICAM_N
• Protein Families: ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)
• Gene Summary: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
  Transcript Variant: This variant (1) encodes the longest isoform (1).