Pentraxin 3 (PTX3) (NM_002852) Human Untagged Clone

CAT#: SC321918

PTX3 (untagged)-Human pentraxin 3, long (PTX3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Pentraxin 3
• Synonyms: TNFAIP5; TSG-14
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002852.2 CATTTATTAAGGACTCTCTGCTCCAGCCTCTCACTCTCACTCTCCTCCGCTCAAACTCAG
  CTCACTTGAGAGTCTCCTCCCGCCAGCTGTGGAAAGAACTTTGCGTCTCTCCAGCAATGC
  ATCTCCTTGCGATTCTGTTTTGTGCTCTCTGGTCTGCAGTGTTGGCCGAGAACTCGGATG
  ATTATGATCTCATGTATGTGAATTTGGACAACGAAATAGACAATGGACTCCATCCCACTG
  AGGACCCCACGCCGTGCGACTGCGGTCAGGAGCACTCGGAATGGGACAAGCTCTTCATCA
  TGCTGGAGAACTCGCAGATGAGAGAGCGCATGCTGCTGCAAGCCACGGACGACGTCCTGC
  GGGGCGAGCTGCAGAGGCTGCGGGAGGAGCTGGGCCGGCTCGCGGAAAGCCTGGCGAGGC
  CGTGCGCGCCGGGGGCTCCCGCAGAGGCCAGGCTGACCAGTGCTCTGGACGAGCTGCTGC
  AGGCGACCCGCGACGCGGGCCGCAGGCTGGCGCGTATGGAGGGCGCGGAGGCGCAGCGCC
  CAGAGGAGGCGGGGCGCGCCCTGGCCGCGGTGCTAGAGGAGCTGCGGCAGACGCGAGCCG
  ACCTGCACGCGGTGCAGGGCTGGGCTGCCCGGAGCTGGCTGCCGGCAGGTTGTGAAACAG
  CTATTTTATTCCCAATGCGTTCCAAGAAGATTTTTGGAAGCGTGCATCCAGTGAGACCAA
  TGAGGCTTGAGTCTTTTAGTGCCTGCATTTGGGTCAAAGCCACAGATGTATTAAACAAAA
  CCATCCTGTTTTCCTATGGCACAAAGAGGAATCCATATGAAATCCAGCTGTATCTCAGCT
  ACCAATCCATAGTGTTTGTGGTGGGTGGAGAGGAGAACAAACTGGTTGCTGAAGCCATGG
  TTTCCCTGGGAAGGTGGACCCACCTGTGCGGCACCTGGAATTCAGAGGAAGGGCTCACAT
  CCTTGTGGGTAAATGGTGAACTGGCGGCTACCACTGTTGAGATGGCCACAGGTCACATTG
  TTCCTGAGGGAGGAATCCTGCAGATTGGCCAAGAAAAGAATGGCTGCTGTGTGGGTGGTG
  GCTTTGATGAAACATTAGCCTTCTCTGGGAGACTCACAGGCTTCAATATCTGGGATAGTG
  TTCTTAGCAATGAAGAGATAAGAGAGACCGGAGGAGCAGAGTCTTGTCACATCCGGGGGA
  ATATTGTTGGGTGGGGAGTCACAGAGATCCAGCCACATGGAGGAGCTCAGTATGTTTCAT
  AAATGTTGTGAAACTCCACTTGAAGCCAAAGAAAGAAACTCACACTTAAAACACATGCCA
  GTTGGGAAGGTCTGAAAACTCAGTGCATAATAGGAACACTTGAGACTAATGAAAGAGAGA
  GTTGAGACCAATCTTTATTTGTACTGGCCAAATACTGAATAAACAGTTGAAGGAAAGACA
  TTGGAAAAAGCTTTTGAGGATAATGTTACTAGACTTTATGCCATGGTGCTTTCAGTTTAA
  TGCTGTGTCTCTGTCAGATAAACTCTCAAATAATTAAAAAGGACTGTATTGTTGAACAGA
  GGGACAATTGTTTTACTTTTCTTTGGTTAATTTTGTTTTGGCCAGAGATGAATTTTACAT
  TGGAAGAATAACAAAATAAGATTTGTTGTCCATTGTTCATTGTTATTGGTATGTACCTTA
  TTACAAAAAAAATGATGAAAACATATTTATACTACAAGGTGACTTAACAACTATAAATGT
  AGTTTATGTGTTATAATCGAATGTCACGTTTTTGAGAAGATAGTCATATAAGTTATATTG
  CAAAAGGGATTTGTATTAATTTAAGACTATTTTTGTAAAGCTCTACTGTAAATAAAATAT
  TTTATAAAACTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_002852
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002852.2, NP_002843.1
• RefSeq Size: 1908 bp
• RefSeq ORF: 1146 bp
• Locus ID: 5806
• UniProt ID: P26022
• Cytogenetics: 3q25.32
• Domains: PTX, LamGL
• Protein Families: Secreted Protein
• Gene Summary: This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions. [provided by RefSeq, Jun 2016]