FOXO3 (NM_201559) Human Untagged Clone

CAT#: SC320321

FOXO3 (untagged)-Human forkhead box O3 (FOXO3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FOXO3
• Synonyms: AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_201559.1 GGGAGGAGGAGGAATGTGGAAGGTGGCGGCGCGCGAGCTGACAGGCGGTTCCTCGGGCGG
  GCTGCGGCGACGGCCCGAGCGCTTCTCCTTCGCCGAGGTTGCGCGCCCCCTCCTCGCCGT
  GCCCCGGGCCCGCGCGGGATCGTGCGTCGTCCCGCCGCGTCCCTGAAGGGAAGGAAGCGA
  GGCGGCGGCGGCGGCGCCCGGGAGCCGGAGCCTTCGCGGCGTCCACGTCCCTCCCCCGCT
  GCACCCCGCCCCGGCGCGAGAGGAGAGCGCGAGAGCCCCAGCCGCGGGCGGGCGGGCGGC
  GAAGATGGCAGAGGCACCGGCTTCCCCGGCCCCGCTCTCTCCGCTCGAAGTGGAGCTGGA
  CCCGGAGTTCGAGCCCCAGAGCCGTCCGCGATCCTGTACGTGGCCCCTGCAAAGGCCGGA
  GCTCCAAGCGAGCCCTGCCAAGCCCTCGGGGGAGACGGCCGCCGACTCCATGATCCCCGA
  GGAGGAGGACGATGAAGACGACGAGGACGGCGGGGGACGGGCCGGCTCGGCCATGGCGAT
  CGGCGGCGGCGGCGGGAGCGGCACGCTGGGCTCCGGGCTGCTCCTTGAGGACTCGGCCCG
  GGTGCTGGCACCCGGAGGGCAAGACCCCGGGTCTGGGCCAGCCACCGCGGCGGGCGGGCT
  GAGCGGGGGTACACAGGCGCTGCTGCAGCCTCAGCAACCGCTGCCACCGCCGCAGCCGGG
  GGCGGCTGGGGGCTCCGGGCAGCCGAGGAAATGTTCGTCGCGGCGGAACGCCTGGGGAAA
  CCTGTCCTACGCGGACCTGATCACCCGCGCCATCGAGAGCTCCCCGGACAAACGGCTCAC
  TCTGTCCCAGATCTACGAGTGGATGGTGCGTTGCGTGCCCTACTTCAAGGATAAGGGCGA
  CAGCAACAGCTCTGCCGGCTGGAAGAACTCCATCCGGCACAACCTGTCACTGCATAGTCG
  ATTCATGCGGGTCCAGAATGAGGGAACTGGCAAGAGCTCTTGGTGGATCATCAACCCTGA
  TGGGGGGAAGAGCGGAAAAGCCCCCCGGCGGCGGGCTGTCTCCATGGACAATAGCAACAA
  GTATACCAAGAGCCGTGGCCGCGCAGCCAAGAAGAAGGCAGCCCTGCAGACAGCCCCCGA
  ATCAGCTGACGACAGTCCCTCCCAGCTCTCCAAGTGGCCTGGCAGCCCCACGTCACGCAG
  CAGTGATGAGCTGGATGCGTGGACGGACTTCCGTTCACGCACCAATTCTAACGCCAGCAC
  AGTCAGTGGCCGCCTGTCGCCCATCATGGCAAGCACAGAGTTGGATGAAGTCCAGGACGA
  TGATGCGCCTCTCTCGCCCATGCTCTACAGCAGCTCAGCCAGCCTGTCACCTTCAGTAAG
  CAAGCCGTGCACGGTGGAACTGCCACGGCTGACTGATATGGCAGGCACCATGAATCTGAA
  TGATGGGCTGACTGAAAACCTCATGGACGACCTGCTGGATAACATCACGCTCCCGCCATC
  CCAGCCATCGCCCACTGGGGGACTCATGCAGCGGAGCTCTAGCTTCCCGTATACCACCAA
  GGGCTCGGGCCTGGGCTCCCCAACCAGCTCCTTTAACAGCACGGTGTTCGGACCTTCATC
  TCTGAACTCCCTACGCCAGTCTCCCATGCAGACCATCCAAGAGAACAAGCCAGCTACCTT
  CTCTTCCATGTCACACTATGGTAACCAGACACTCCAGGACCTGCTCACTTCGGACTCACT
  TAGCCACAGCGATGTCATGATGACACAGTCGGACCCCTTGATGTCTCAGGCCAGCACCGC
  TGTGTCTGCCCAGAATTCCCGCCGGAACGTGATGCTTCGCAATGATCCGATGATGTCCTT
  TGCTGCCCAGCCTAACCAGGGAAGTTTGGTCAATCAGAACTTGCTCCACCACCAGCACCA
  AACCCAGGGCGCTCTTGGTGGCAGCCGTGCCTTGTCGAATTCTGTCAGCAACATGGGCTT
  GAGTGAGTCCAGCAGCCTTGGGTCAGCCAAACACCAGCAGCAGTCTCCTGTCAGCCAGTC
  TATGCAAACCCTCTCGGACTCTCTCTCAGGCTCCTCCTTGTACTCAACTAGTGCAAACCT
  GCCCGTCATGGGCCATGAGAAGTTCCCCAGCGACTTGGACCTGGACATGTTCAATGGGAG
  CTTGGAATGTGACATGGAGTCCATTATCCGTAGTGAACTCATGGATGCTGATGGGTTGGA
  TTTTAACTTTGATTCCCTCATCTCCACACAGAATGTTGTTGGTTTGAACGTGGGGAACTT
  CACTGGTGCTAAGCAGGCCTCATCTCAGAGCTGGGTGCCAGGCTGAAGGATCACTGAGGA
  AGGGGAAGTGGGCAAAGCAGACCCTCAAACTGACACAAGACCTACAGAGAAAACCCTTTG
  CCAAATCTGCTCTCAGCAAGTGGACAGTGATACCGTTTACAGCTTAACACCTTTGTGAAT
  CCCACGCCATTTTCCTAACCCAGCAGAGACTGTTAATGGCCCCTTACCCTGGGTGAAGCA
  CTTACCCTTGGAACAGAACTCTAAAAAGTATGCAAAATCTTCCTTGTACAGGGTGGTGAG
  CCGCCTGCCAGTGGAGGACAGCACCCCTCAGCACCACCCACCCTCATTCAGAGCACACCG
  TGAGCCCCCGTCGGCCATTCTGTGGTGTTTTAATATTGCGATGGTTTATGGGACGTTTTA
  AGTGTTGTTCTTGTGTTTGTTTTCCTTTGACTTTCTGAGTTTTTCACATGCATTAACTTG
  CGGTATTTTTCTGTTAAAATGTTAACCGTCCTTCCCCTAGCAAATTTAAAAACAGAAAGA
  AAATGTTGTACCAGTTACCATTCCGGGTTCGAGCATCACAAGCTTTTGAGCGCATGGAAC
  TCCATAAACTAACAAATTACATAAACTAAAGGGGGATTTTCTTTCTTCTTTTGTTTGGTA
  GAAAATTATCCTTTTCTAAAAACTGAACAATGGCACAATTGTTTGCTATGTGCACCCGTC
  CAGGACAGAACCGTGCATAGGCAAAAGGAGTGGAGCACAGCGTCCGGCCCAGTGTGTTTC
  CGGTTCTGAGTCAGGGTGATCTGTGGACGGGACCCCAGCACCAAGTCTACGGGTGCCAGA
  TCAGTAGGGCCTGTGATTTCCTGTCAGTGTCCTCAGCTAATGTGAACAGTGTTGGTCTGC
  TGGTTAGAAACTAGAATATTGATATTTTCAGGAAAGAAATCAGCTCAGCTCTCCACTCAT
  TGCCAAATGTCACTAAAGGGTTTAGTTTTAAGGAGAAAGAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_201559
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_201559.1, NP_963853.1
• RefSeq Size: 3311 bp
• RefSeq ORF: 2022 bp
• Locus ID: 2309
• UniProt ID: O43524
• Cytogenetics: 6q21
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Chemokine signaling pathway, Endometrial cancer, Neurotrophin signaling pathway, Non-small cell lung cancer
• Gene Summary: This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) differs in the 5' end compared to variant 1. Both variants encode the same protein.