ABCB6 (NM_005689) Human Untagged Clone

CAT#: SC320214

ABCB6 (untagged)-Human ATP-binding cassette, sub-family B (MDR/TAP), member 6 (ABCB6), nuclear gene encoding mitochondrial protein

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ABCB6
• Synonyms: ABC; LAN; MTABC3; PRP; umat
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005689.1 GTTGGCAGAAGGGTCCCGGGCCCAGAGCCAGCGGGGCCGTGCTGAGACGGCGTACGTGCC
  CTGCGTGAGTGCGTGGCGGCGGCGCGTGCGCTAGGGGAGTGGGCGGTGAGGCCTGGTCCA
  CGTGCGTCCCTTCCCGGGACCCCCGCAGCTTGGCGCCCAGCGGCTACGTGAGCCAAGGCA
  CCCGGATGTCCGCGCCCCTCTCCGAGTGACAAGTCCCGGCCTCCGGTCCCGCAGTGCCCG
  CAGCCTCGGCCGGCGTCCACGCATTGCCATGGTGACTGTGGGCAACTACTGCGAGGCCGA
  AGGGCCCGTGGGTCCGGCCTGGATGCAGGATGGCCTGAGTCCCTGCTTCTTCTTCACGCT
  CGTGCCCTCGACGCGGATGGCTCTAGGGACTCTGGCCTTGGTGCTGGCTCTTCCCTGCAG
  ACGCCGGGAGCGGCCCGCTGGTGCTGATTCGCTGTCTTGGGGGGCCGGCCCTCGCATCTC
  TCCCTACGTGCTGCAGCTGCTTCTGGCCACACTTCAGGCGGCGCTGCCCCTGGCCGGCCT
  GGCTGGCCGGGTGGGCACTGCCCGGGGGGCCCCACTGCCAAGCTATCTACTTCTGGCCTC
  CGTGCTGGAGAGTCTGGCCGGCGCCTGTGGCCTGTGGCTGCTTGTCGTGGAGCGGAGCCA
  GGCACGGCAGCGTCTGGCAATGGGCATCTGGATCAAGTTCAGGCACAGCCCTGGTCTCCT
  GCTCCTCTGGACTGTGGCGTTTGCAGCTGAGAACTTGGCCCTGGTGTCTTGGAACAGCCC
  ACAGTGGTGGTGGGCAAGGGCAGACTTGGGCCAGCAGGTTCAGTTTAGCCTGTGGGTGCT
  GCGGTATGTGGTCTCTGGAGGGCTGTTTGTCCTGGGTCTCTGGGCCCCTGGACTTCGTCC
  CCAGTCCTATACATTGCAGGTTCATGAAGAGGACCAAGATGTGGAAAGGAGCCAGGTTCG
  GTCAGCAGCCCAACAGTCTACCTGGCGAGATTTTGGCAGGAAGCTCCGCCTCCTGAGTGG
  CTACCTGTGGCCTCGAGGGAGTCCAGCTCTGCAGCTGGTGGTGCTCATCTGCCTGGGGCT
  CATGGGTTTGGAACGGGCACTCAATGTGTTGGTGCCTATATTCTATAGGAACATTGTGAA
  CTTGCTGACTGAGAAGGCACCTTGGAACTCTCTGGCCTGGACTGTTACCAGTTACGTCTT
  CCTCAAGTTCCTCCAGGGGGGTGGCACTGGCAGTACAGGCTTCGTGAGCAACCTGCGCAC
  CTTCCTGTGGATCCGGGTGCAGCAGTTCACGTCTCGGCGGGTGGAGCTGCTCATCTTCTC
  CCACCTGCACGAGCTCTCACTGCGCTGGCACCTGGGGCGCCGCACAGGGGAGGTGCTGCG
  GATCGCGGATCGGGGCACATCCAGTGTCACAGGGCTGCTCAGCTACCTGGTGTTCAATGT
  CATCCCCACGCTGGCCGACATCATCATTGGCATCATCTACTTCAGCATGTTCTTCAACGC
  CTGGTTTGGCCTCATTGTGTTCCTGTGCATGAGTCTTTACCTCACCCTGACCATTGTGGT
  CACTGAGTGGAGAACCAAGTTTCGTCGTGCTATGAACACACAGGAGAACGCTACCCGGGC
  ACGAGCAGTGGACTCTCTGCTAAACTTCGAGACGGTGAAGTATTACAACGCCGAGAGTTA
  CGAAGTGGAACGCTATCGAGAGGCCATCATCAAATATCAGGGTTTGGAGTGGAAGTCGAG
  CGCTTCACTGGTTTTACTAAATCAGACCCAGAACCTGGTAATTGGGCTCGGGCTCCTCGC
  CGGCTCCCTGCTTTGCGCATACTTTGTCACTGAGCAGAAGCTACAGGTTGGGGACTATGT
  GCTCTTTGGCACCTACATTATCCAGCTGTACATGCCCCTCAATTGGTTTGGCACCTACTA
  CAGGATGATCCAGACCAACTTCATTGACATGGAGAACATGTTTGACTTGCTGAAAGAGGA
  GACAGAAGTGAAGGACCTTCCTGGAGCAGGGCCCCTTCGCTTTCAGAAGGGCCGTATTGA
  GTTTGAGAACGTGCACTTCAGCTATGCCGATGGGCGGGAGACTCTGCAGGACGTGTCTTT
  CACTGTGATGCCTGGACAGACACTTGCCCTGGTGGGCCCATCTGGGGCAGGGAAGAGCAC
  AATTTTGCGCCTGCTGTTTCGCTTCTACGACATCAGCTCTGGCTGCATCCGAATAGATGG
  GCAGGACATTTCACAGGTGACCCAGGCCTCTCTCCGGTCTCACATTGGAGTTGTGCCCCA
  AGACACTGTCCTCTTTAATGACACCATCGCCGACAATATCCGTTACGGCCGTGTCACAGC
  TGGGAATGATGAGGTGGAGGCTGCTGCTCAGGCTGCAGGCATCCATGATGCCATTATGGC
  TTTCCCTGAAGGGTACAGGACACAGGTGGGCGAGCGGGGACTGAAGCTGAGCGGCGGGGA
  GAAGCAGCGCGTCGCCATTGCCCGCACCATCCTCAAGGCTCCGGGCATCATTCTGCTGGA
  TGAGGCAACGTCAGCGCTGGATACATCTAATGAGAGGGCCATCCAGGCTTCTCTGGCCAA
  AGTCTGTGCCAACCGCACCACCATCGTAGTGGCACACAGGCTCTCAACTGTGGTCAATGC
  TGACCAGATCCTCGTCATCAAGGATGGCTGCATCGTGGAGAGGGGACGACACGAGGCTCT
  GTTGTCCCGAGGTGGGGTGTATGCTGACATGTGGCAGCTGCAGCAGGGACAGGAAGAAAC
  CTCTGAAGACACTAAGCCTCAGACCATGGAACGGTGACAAAAGTTTGGCCACTTCCCTCT
  CAAAGACTAACCCAGAAGGGAATAAGATGTGTCTCCTTTCCCTGGCTTATTTCATCCTGG
  TCTTGGGGTATGGTGCTAGCTATGGTAAGGGAAAGGGACCTTTCCGAAAAACATCTTTTG
  GGGAAATAAAAATGTGGACTGTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_005689
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005689.1, NP_005680.1
• RefSeq Size: 2993 bp
• RefSeq ORF: 2529 bp
• Locus ID: 10058
• UniProt ID: Q9NP58
• Cytogenetics: 2q35
• Domains: ABC_membrane, ABC_tran, AAA
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ABC transporters
• Gene Summary: This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. This protein is a member of the heavy metal importer subfamily and plays a role in porphyrin transport. This gene is the molecular basis of the Langereis (Lan) blood group antigen and mutations in this gene underlie familial pseudohyperkalemia and dyschromatosis universalis hereditaria. [provided by RefSeq, Mar 2017]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.