CCR4 (NM_005508) Human Untagged Clone

CAT#: SC319943

CCR4 (untagged)-Human chemokine (C-C motif) receptor 4 (CCR4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCR4
• Synonyms: CC-CKR-4; CD194; ChemR13; CKR4; CMKBR4; HGCN:14099; K5-5
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005508.4 GCTCACAGGAAGCCACGCACCCTTGAAAGGCACCGGGTCCTTCTTAGCATCGTGCTTCCT
  GAGCAAGCCTGGCATTGCCTCACAGACCTTCCTCAGAGCCGCTTTCAGAAAAGCAAGCTG
  CTTCTGGTTGGGCCCAGACCTGCCTTGAGGAGCCTGTAGAGTTAAAAAATGAACCCCACG
  GATATAGCAGACACCACCCTCGATGAAAGCATATACAGCAATTACTATCTGTATGAAAGT
  ATCCCCAAGCCTTGCACCAAAGAAGGCATCAAGGCATTTGGGGAGCTCTTCCTGCCCCCA
  CTGTATTCCTTGGTTTTTGTATTTGGTCTGCTTGGAAATTCTGTGGTGGTTCTGGTCCTG
  TTCAAATACAAGCGGCTCAGGTCCATGACTGATGTGTACCTGCTCAACCTTGCCATCTCG
  GATCTGCTCTTCGTGTTTTCCCTCCCTTTTTGGGGCTACTATGCAGCAGACCAGTGGGTT
  TTTGGGCTAGGTCTGTGCAAGATGATTTCCTGGATGTACTTGGTGGGCTTTTACAGTGGC
  ATATTCTTTGTCATGCTCATGAGCATTGATAGATACCTGGCAATTGTGCACGCGGTGTTT
  TCCTTGAGGGCAAGGACCTTGACTTATGGGGTCATCACCAGTTTGGCTACATGGTCAGTG
  GCTGTGTTCGCCTCCCTTCCTGGCTTTCTGTTCAGCACTTGTTATACTGAGCGCAACCAT
  ACCTACTGCAAAACCAAGTACTCTCTCAACTCCACGACGTGGAAGGTTCTCAGCTCCCTG
  GAAATCAACATTCTCGGATTGGTGATCCCCTTAGGGATCATGCTGTTTTGCTACTCCATG
  ATCATCAGGACCTTGCAGCATTGTAAAAATGAGAAGAAGAACAAGGCGGTGAAGATGATC
  TTTGCCGTGGTGGTCCTCTTCCTTGGGTTCTGGACACCTTACAACATAGTGCTCTTCCTA
  GAGACCCTGGTGGAGCTAGAAGTCCTTCAGGACTGCACCTTTGAAAGATACTTGGACTAT
  GCCATCCAGGCCACAGAAACTCTGGCTTTTGTTCACTGCTGCCTTAATCCCATCATCTAC
  TTTTTTCTGGGGGAGAAATTTCGCAAGTACATCCTACAGCTCTTCAAAACCTGCAGGGGC
  CTTTTTGTGCTCTGCCAATACTGTGGGCTCCTCCAAATTTACTCTGCTGACACCCCCAGC
  TCATCTTACACGCAGTCCACCATGGATCATGATCTCCATGATGCTCTGTAGAAAAATGAA
  ATGGTGAAATGCAGAGTCAATGAACTTTCCACATTCAGAGCTTACTTAAAATTGTATTTT
  AGTAAGAGATTCCTGAGCCAGTGTCAGGAGGAAGGCTTACACCCACAGTGGAAAGACAGC
  TTCTCATCCTGCAGGCAGCTTTTTCTCTCCCACTAGACAAGTCCAGCCTGGCAAGGGTTC
  ACCTGGGCTGAGGCATCCTTCCTCACACCAGGCTTGCCTGCAGGCATGAGTCAGTCTGAT
  GAGAACTCTGAGCAGTGCTTGAATGAAGTTGTAGGTAATATTGCAAGGCAAAGACTATTC
  CCTTCTAACCTGAACTGATGGGTTTCTCCAGAGGGAATTGCAGAGTACTGGCTGATGGAG
  TAAATCGCTACCTTTTGCTGTGGCAAATGGGCCCTCTAATTAATTTCTTGCTTTTGCGGA
  ACAATATAGATAACTGTTTTTCTAATAACATATCTCAGGCAAAGTATATTCCATTGAGCC
  AGATGTATGAAGAAACAATTAGTGAAGTGATGAAACCAGATCTCAATTATTTATTGTAAA
  GGATTATCTGTTAATTGAAACCAAACTTTTTATACTGATATAAGGGTAAGGATATGAAGA
  CATTAGCCAAGGTCTGCTTTCCAAACGTGAACTACAAGGCATTCAAAATCCAAACATATT
  TATGAAAATTCAAACACAGTTTCTCACTTGTTTGTGGACATGTTTTGTTCTAATTTTAAC
  AGAGGAATATTAAAAAATTTTAAATAGGCTGGGATTACAGGTGTGAGCCATCACGCCCGG
  CCACTTGTTTATTTTTTATTTTATTTTATTTTATTTTTGAGATGGAGTCTCACTCTGTCA
  CCCAAGCTGGAGTGCAGTGGCACTCGGTTCACTGCAAAGTCTGCCTCCCAGGTTCAAGCG
  ATTCTCCTGCCTCAGCTTCTCAAGCAGCTGGGATTAGAGGTGTGCACCACTACGCCAGGC
  TAGTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTAGTCTTGAAC
  TCCTGACCTCAGGTGATCTGCCTGCTTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGA
  GCCACCTCGCCCAGCCAAGGTCTTTTACTTGTTTATAAACAGTCTCTTCATAATTAAAAT
  TAAGGATTAATAAAGTATGACAATACCTCCTTAATCATTTTGAAGTGCCTGCTATCAATT
  GAAATAAAAACAATCAACCAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_005508
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005508.4, NP_005499.1
• RefSeq Size: 1657 bp
• RefSeq ORF: 1083 bp
• Locus ID: 1233
• UniProt ID: P51679
• Cytogenetics: 3p22.3
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction
• Gene Summary: The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008]