CD71 (TFRC) (NM_003234) Human Untagged Clone

CAT#: SC319387

TFRC (untagged)-Human transferrin receptor (p90, CD71) (TFRC), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CD71
• Synonyms: CD71; IMD46; p90; T9; TFR; TFR1; TR; TRFR
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003234 edited
  CGGGTGGCGGCTCGGGACGGAGGACGCGCTAGTGTTCTTCTGTGTGGCAGTTCAGAATGA
  TGGATCAAGCTAGATCAGCATTCTCTAACTTGTTTGGTGGAGAACCATTGTCATATACCC
  GGTTCAGCCTGGCTCGGCAAGTAGATGGCGATAACAGTCATGTGGAGATGAAACTTGCTG
  TAGATGAAGAAGAAAATGCTGACAATAACACAAAGGCCAATGTCACAAAACCAAAAAGGT
  GTAGTGGAAGTATCTGCTATGGGACTATTGCTGTGATCGTCTTTTTCTTGATTGGATTTA
  TGATTGGCTACTTGGGCTATTGTAAAGGGGTAGAACCAAAAACTGAGTGTGAGAGACTGG
  CAGGAACCGAGTCTCCAGTGAGGGAGGAGCCAGGAGAGGACTTCCCTGCAGCACGTCGCT
  TATATTGGGATGACCTGAAGAGAAAGTTGTCGGAGAAACTGGACAGCACAGACTTCACCG
  GCACCATCAAGCTGCTGAATGAAAATTCATATGTCCCTCGTGAGGCTGGATCTCAAAAAG
  ATGAAAATCTTGCGTTGTATGTTGAAAATCAATTTCGTGAATTTAAACTCAGCAAAGTCT
  GGCGTGATCAACATTTTGTTAAGATTCAGGTCAAAGACAGCGCTCAAAACTCGGTGATCA
  TAGTTGATAAGAACGGTAGACTTGTTTACCTGGTGGAGAATCCTGGGGGTTATGTGGCGT
  ATAGTAAGGCTGCAACAGTTACTGGTAAACTGGTCCATGCTAATTTTGGTACTAAAAAAG
  ATTTTGAGGATTTATACACTCCTGTGAATGGATCTATAGTGATTGTCAGAGCAGGGAAAA
  TCACCTTTGCAGAAAAGGTTGCAAATGCTGAAAGCTTAAATGCAATTGGTGTGTTGATAT
  ACATGGACCAGACTAAATTTCCCATTGTTAACGCAGAACTTTCATTCTTTGGACATGCTC
  ATCTGGGGACAGGTGACCCTTACACACCTGGATTCCCTTCCTTCAATCACACTCAGTTTC
  CACCATCTCGGTCATCAGGATTGCCTAATATACCTGTCCAGACAATCTCCAGAGCTGCTG
  CAGAAAAGCTGTTTGGGAATATGGAAGGAGACTGTCCCTCTGACTGGAAAACAGACTCTA
  CATGTAGGATGGTAACCTCAGAAAGCAAGAATGTGAAGCTCACTGTGAGCAATGTGCTGA
  AAGAGATAAAAATTCTTAACATCTTTGGAGTTATTAAAGGCTTTGTAGAACCAGATCACT
  ATGTTGTAGTTGGGGCCCAGAGAGATGCATGGGGCCCTGGAGCTGCAAAATCCGGTGTAG
  GCACAGCTCTCCTATTGAAACTTGCCCAGATGTTCTCAGATATGGTCTTAAAAGATGGGT
  TTCAGCCCAGCAGAAGCATTATCTTTGCCAGTTGGAGTGCTGGAGACTTTGGATCGGTTG
  GTGCCACTGAATGGCTAGAGGGATACCTTTCGTCCCTGCATTTAAAGGCTTTCACTTATA
  TTAATCTGGATAAAGCGGTTCTTGGTACCAGCAACTTCAAGGTTTCTGCCAGCCCACTGT
  TGTATACGCTTATTGAGAAAACAATGCAAAATGTGAAGCATCCGGTTACTGGGCAATTTC
  TATATCAGGACAGCAACTGGGCCAGCAAAGTTGAGAAACTCACTTTAGACAATGCTGCTT
  TCCCTTTCCTTGCATATTCTGGAATCCCAGCAGTTTCTTTCTGTTTTTGCGAGGACACAG
  ATTATCCTTATTTGGGTACCACCATGGACACCTATAAGGAACTGATTGAGAGGATTCCTG
  AGTTGAACAAAGTGGCACGAGCAGCTGCAGAGGTCGCTGGTCAGTTCGTGATTAAACTAA
  CCCATGATGTTGAATTGAACCTGGACTATGAGAGGTACAACAGCCAACTGCTTTCATTTG
  TGAGGGATCTGAACCAATACAGAGCAGACATAAAGGAAATGGGCCTGAGTTTACAGTGGC
  TGTATTCTGCTCGTGGAGACTTCTTCCGTGCTACTTCCAGACTAACAACAGATTTCGGGA
  ATGCTGAGAAAACAGACAGATTTGTCATGAAGAAACTCAATGATCGTGTCATGAGAGTGG
  AGTATCACTTCCTCTCTCCCTACGTATCTCCAAAAGAGTCTCCTTTCCGACATGTCTTCT
  GGGGCTCCGGCTCTCACACGCTGCCAGCTTTACTGGAGAACTTGAAACTGCGTAAACAAA
  ATAACGGTGCTTTTAATGAAACGCTGTTCAGAAACCAGTTGGCTCTAGCTACTTGGACTA
  TTCAGGGAGCTGCAAATGCCCTCTCTGGTGACGTTTGGGACATTGACAATGAGTTTTAAA
  TGTGATACCCATAGCTTCCATGAGAACAGCAGGGTAGTCTGGTTTCTAGACTTGTGCTGA
  TCGTGCTAAATTTTCAGTAGGGCTACAAAACCTGATGTTAAAATTCCATCCCATCATCTT
  GGTACTACTAGATGTCTTTAGGCAGCAGCTTTTAATACAGGGTAGATAACCTGTACTTCA
  AGTTAAAGTGAATAACCACTTAAAAAATGTCCATGATGGAATATTCCCCTATCTCTAGAA
  TTTTAAGTGCTTTGTAATGGGAACTGCCTCTTTCCTGTTGTTGTTAATGAAAATGTCAGA
  AACCAGTTATGTGAATGATCTCTCTGAATCCTAAGGGCTGGTCTCTGCTGAAGGTTGTAA
  GTGGTCGCTTACTTTGAGTGATCCTCCAACTTCATTTGATGCTAAATAGGAGATACCAGG
  TTGAAAGACCTTCTCCAAATGAGATCTAAGCCTTTCCATAAGGAATGTAGCTGGTTTCCT
  CATTCCTGAAAGAAACAGTTAACTTTCAGAAGAGATGGGCTTGTTTTCTTGCCAATGAGG
  TCTGAAATGGAGGTCCTTCTGCTGGATAAAATGAGGTTCAACTGTTGATTGCAGGAATAA
  GGCCTTAATATGTTAACCTCAGTGTCATTTATGAAAAGAGGGGACCAGAAGCCAAAGACT
  TAGTATATTTTCTTTTCCTCTGTCCCTTCCCCCATAAGCCTCCATTTAGTTCTTTGTTAT
  TTTTGTTTCTTCCAAAGCACATTGAAAGAGAACCAGTTTCAGGTGTTTAGTTGCAGACTC
  AGTTTGTCAGACTTTAAAGAATAATATGCTGCCAAATTTTGGCCAAAGTGTTAATCTTAG
  GGGAGAGCTTTCTGTCCTTTTGGCACTGAGATATTTATTGTTTATTTATCAGTGACAGAG
  TTCACTATAAATGGTGTTTTTTTAATAGAATATAATTATCGGAAGCAGTGCCTTCCATAA
  TTATGACAGTTATACTGTCGGTTTTTTTTAAATAAAAGCAGCATCTGCTAATAAAACCCA
  ACAGATACTGGAAGTTTTGCATTTATGGTCAACACTTAAGGGTTTTAGAAAACAGCCGTC
  AGCCAAATGTAATTGAATAAAGTTGAAGCTAAGATTTAGAGATGAATTAAATTTAATTAG
  GGGTTGCTAAGAAGCGAGCACTGACCAGATAAGAATGCTGGTTTTCCTAAATGCAGTGAA
  TTGTGACCAAGTTATAAATCAATGTCACTTAAAGGCTGTGGTAGTACTCCTGCAAAATTT
  TATAGCTCAGTTTATCCAAGGTGTAACTCTAATTCCCATTTTGCAAAATTTCCAGTACCT
  TTGTCACAATCCTAACACATTATCGGGAGCAGTGTCTTCCATAATGTATAAAGAACAAGG
  TAGTTTTTACCTACCACAGTGTCTGTATCGGAGACAGTGATCTCCATATGTTACACTAAG
  GGTGTAAGTAATTATCGGGAACAGTGTTTCCCATAATTTTCTTCATGCAATGACATCTTC
  AAAGCTTGAAGATCGTTAGTATCTAACATGTATCCCAACTCCTATAATTCCCTATCTTTT
  AGTTTTAGTTGCAGAAACATTTTGTGGTCATTAAGCATTGGGTGGGTAAATTCAACCACT
  GTAAAATGAAATTACTACAAAATTTGAAATTTAGCTTGGGTTTTTGTTACCTTTATGGTT
  TCTCCAGGTCCTCTACTTAATGAGATAGTAGCATACATTTATAATGTTTGCTATTGACAA
  GTCATTTTAACTTTATCACATTATTTGCATGTTACCTCCTATAAACTTAGTGCGGACAAG
  TTTTAATCCAGAATTGACCTTTTGACTTAAAGCAGGGGGACTTTGTATAGAAGGTTTGGG
  GGCTGTGGGGAAGGAGAGTCCCCTGAAGGTCTGACACGTCTGCCTACCCATTCGTGGTGA
  TCAATTAAATGTAGGTATGAATAAGTTCGAAGCTCCGTGAGTGAACCATCATTATAAACG
  TGATGATCAGCTGTTTGTCATAGGGCAGTTGGAAACGGCCTCCTAGGGAAAAGTTCATAG
  GGTCTCTTCAGGTTCTTAGTGTCACTTACCTAGATTTACAGCCTCACTTGAATGTGTCAC
  TACTCACAGTCTCTTTAATCTTCAGTTTTATCTTTAATCTCCTCTTTTATCTTGGACTGA
  CATTTAGCGTAGCTAAGTGAAAAGGTCATAGCTGAGATTCCTGGTTCGGGTGTTACGCAC
  ACGTACTTAAATGAAAGCATGTGGCATGTTCATCGTATAACACAATATGAATACAGGGCA
  TGCATTTTGCAGCAGTGAGTCTCTTCAGAAAACCCTTTTCTACAGTTAGGGTTGAGTTAC
  TTCCTATCAAGCCAGTACGTGCTAACAGGCTCAATATTCCTGAATGAAATATCAGACTAG
  TGACAAGCTCCTGGTCTTGAGATGTCTTCTCGTTAAGGAGATGGGCCTTTTGGAGGTAAA
  GGATAAAATGAATGAGTTCTGTCATGATTCACTATTCTAGAACTTGCATGACCTTTACTG
  TGTTAGCTCTTTGAATGTTCTTGAAATTTTAGACTTTCTTTGTAAACAAATAATATGTCC
  TTATCATTGTATAAAAGCTGTTATGTGCAACAGTGTGGAGATTCCTTGTCTGATTTAATA
  AAATACTTAAACACTGAAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_003234
• Insert Size: 5300 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003234.1, NP_003225.1
• RefSeq Size: 5010 bp
• RefSeq ORF: 2283 bp
• Locus ID: 7037
• UniProt ID: P02786
• Cytogenetics: 3q29
• Domains: PA, TFR_dimer, Peptidase_M28
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protease, Secreted Protein, Transmembrane
• Protein Pathways: Endocytosis, Hematopoietic cell lineage
• Gene Summary: This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Variants 1 and 2 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.