IFNGR2 (NM_005534) Human Untagged Clone

CAT#: SC319060

IFNGR2 (untagged)-Human interferon gamma receptor 2 (interferon gamma transducer 1) (IFNGR2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IFNGR2
• Synonyms: AF-1; IFGR2; IFNGT1; IMD28
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005534 edited
  GCGGGCCCTGCGCGCCCTGCGCTCGCCATGGCGGTTTGGGCGGCGACGTGAGCGGCTCCG
  CGGACCCCGAGCGGGGCCCCGGCCGCGACCTGAGCCGCCGCCGAGCGCCCGGGGCCATGC
  GACCGACGCTGCTGTGGTCGCTGCTGCTGCTGCTCGGAGTCTTCGCCGCCGCCGCCGCGG
  CCCCGCCAGACCCTCTTTCCCAGCTGCCCGCTCCTCAGCACCCGAAGATTCGCCTGTACA
  ACGCAGAGCAGGTCCTGAGTTGGGAGCCAGTGGCCCTGAGCAATAGCACGAGGCCTGTTG
  TCTACCAAGTGCAGTTTAAATACACCGACAGTAAATGGTTCACGGCCGACATCATGTCCA
  TAGGGGTGAATTGTACACAGATCACAGCAACAGAGTGTGACTTCACTGCCGCCAGTCCCT
  CAGCAGGCTTCCCAATGGATTTCAATGTCACTCTACGCCTTCGAGCTGAGCTGGGAGCAC
  TCCATTCTGCCTGGGTGACAATGCCTTGGTTTCAACACTATCGGAATGTGACTGTCGGGC
  CTCCAGAAAACATTGAGGTGACCCCAGGAGAAGGCTCCCTCATCATCAGGTTCTCCTCTC
  CCTTTGACATCGCTGATACCTCCACGGCCTTTTTTTGTTATTATGTCCATTACTGGGAAA
  AAGGAGGAATCCAACAGGTCAAAGGCCCTTTCAGAAGCAACTCCATTTCATTGGATAACT
  TAAAACCCTCCAGAGTGTACTGTTTACAAGTCCAGGCACAACTGCTTTGGAACAAAAGTA
  ACATCTTTAGAGTCGGGCATTTAAGCAACATATCTTGCTACGAAACAATGGCAGATGCCT
  CCACTGAGCTTCAGCAAGTCATCCTGATCTCCGTGGGAACATTTTCGTTGCTGTCGGTGC
  TGGCAGGAGCCTGTTTCTTCCTGGTCCTGAAATATAGAGGCCTGATTAAATACTGGTTTC
  ACACTCCACCAAGCATCCCATTACAGATAGAAGAGTATTTAAAAGACCCAACTCAGCCCA
  TCTTAGAGGCCTTGGACAAGGACAGCTCACCAAAGGATGACGTCTGGGACTCTGTGTCCA
  TTATCTCGTTTCCGGAAAAGGAGCAAGAAGATGTTCTCCAAACGCTTTGAACCAAAGCAT
  GGGCCTAGCCCACTGGCTCCCTGGAAGAGATCAAGCCATCGGAGCTGCTAGAGTTCTGTC
  TGGACTTTCCAGAGACCAGTATTCCCTTTTGCTGCCTCTAAAAGGCCTGTCCCTGCAGAC
  ATGAGAGACAGCAGGTCTCATGGGGGTGACAAGCTTTTTTTTTTTTCTTAAAGAATTTTC
  AAAATCAAATTCCAGAATGATTTTACGGAGATATCCCAGGAAAATTAAGGCTTCTCTTAA
  ACACTAAAAAGGCATGTAATTGCTTGTTAGCAAAATGGATATGACACATCTCTGATACTT
  TTTTCATTATTGGTTGGGCTGAGCAGTCAGAAGACCTGGTCGTCGTCTTGACTTTGGCAA
  ATGAGCCGGAGCCCCTTGGGCAGGTCACACAACCTGTCCCAGCGAGGGACACCGAGTGGC
  CCTTCATGTACATCCATGGTGTGCTGGCTTAAAATGTAATTAATCTTGTAAATATACTCC
  TAGTAATTTAAGATTTTGTTTTTAAACTGGAAATAAAAGATTGTATAGTGCATGTTTTTT
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_005534
• Insert Size: 1700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: no
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005534.2, NP_005525.2
• RefSeq Size: 2219 bp
• RefSeq ORF: 1014 bp
• Locus ID: 3460
• UniProt ID: P38484
• Cytogenetics: 21q22.11
• Domains: FN3
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity
• Gene Summary: This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. [provided by RefSeq, Jul 2008]