GJC2 (NM_020435) Human Untagged Clone

SKU SC313476

GJC2 (untagged)-Human gap junction protein, gamma 2, 47kDa (GJC2)

Product Data

• Type: Human Untagged Clone
• Target Symbol: GJC2
• Synonyms: CX46.6; Cx47; GJA12; HLD2; LMPH1C; LMPHM3; PMLDAR; SPG44
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_020435 edited; GCCCCCGGTCGCTTGCTCCAGGGCAGGTGGACTGAGCTTCGGAGGCTGGGGCTGGCCTCT; GACCTGCTTGGGCTTGGAGAGCCCTGCCCGCTGCCCTGCCCCCCAGGACAATCAGGGATT; CAGACCCTGAGGCCGAGGGGGGAACAATGGGGCCCTTGAGGGCCCCTCCTCCAGCCCCCA; TTGTGCTTGGTGGTGAGAGGTGGCCCTGGCTCGGCCACACACCCTCGGGGAGGACCAGCA; TCCAAGCAGGTGGAAGGGCTCTGAGGGAGACTGGAATTTTCTGGCCTGGAGAAGGACCCG; CCCGCCCGCCCCTATGACCAACATGAGCTGGAGCTTCCTGACGCGGCTGCTGGAGGAGAT; CCACAACCACTCCACCTTCGTGGGCAAGGTGTGGCTCACGGTGCTGGTGGTCTTCCGCAT; CGTGCTGACGGCTGTGGGCGGCGAGGCCATCTACTCGGACGAGCAGGCCAAGTTCACTTG; CAACACGCGGCAGCCAGGCTGCGACAACGTCTGCTATGACGCCTTCGCGCCCCTGTCGCA; CGTGCGCTTCTGGGTCTTCCAGATTGTGGTCATCTCCACGCCCTCGGTCATGTACCTGGG; CTACGCCGTGCACCGCCTGGCCCGTGCGTCTGAGCAGGAGCGGCGCCGCGCCCTCCGCCG; CCGCCCGGGGCCACGCCGCGCGCCCCGAGCGCACCTGCCGCCCCCGCACGCCGGCTGGCC; TGAGCCCGCCGACCTGGGCGAGGAGGAGCCCATGCTGGGCCTGGGCGAGGAGGAGGAGGA; GGAGGAGACGGGGGCAGCCGAGGGCGCCGGCGAGGAAGCGGAGGAGGCAGGCGCGGAGGA; GGCGTGCACTAAGGCGGTCGGCGCTGACGGCAAGGCGGCAGGGACCCCGGGCCCGACCGG; GCAACACGATGGGCGGAGGCGCATCCAGCGGGAGGGCCTGATGCGCGTGTACGTGGCCCA; GCTGGTGGCCAGGGCAGCTTTCGAGGTGGCCTTCCTGGTGGGCCAGTACCTGCTGTACGG; CTTCGAGGTGCGACCGTTCTTTCCCTGCAGCCGCCAGCCCTGCCCGCACGTGGTGGACTG; CTTCGTGTCGCGCCCTACTGAAAAGACGGTCTTCCTGCTGGTTATGTACGTGGTCAGCTG; CCTGTGCCTGCTGCTCAACCTCTGTGAGATGGCCCACCTGGGCTTGGGCAGCGCGCAGGA; CGCGGTGCGCGGCCGCCGCGGCCCCCCGGCCTCCGCCCCCGCCCCCGCGCCGCGGCCCCC; GCCCTGCGCCTTCCCTGCGGCGGCCGCTGGCTTGGCCTGCCCGCCCGACTACAGCCTGGT; GGTGCGGGCGGCCGAGCGCGCTCGGGCGCATGACCAGAACCTGGCAAACCTGGCCCTGCA; GGCGCTGCGCGACGGGGCAGCGGCTGGGGACCGCGACCGGGACAGTTCGCCGTGCGTCGG; CCTCCCTGCGGCCTCCCGGGGGCCCCCCAGAGCAGGCGCCCCCGCGTCCCGGACGGGCAG; TGCTACCTCTGCGGGCACTGTCGGGGAGCAGGGCCGGCCCGGCACCCACGAGCGGCCAGG; AGCCAAGCCCAGGGCTGGCTCCGAGAAGGGCAGTGCCAGCAGCAGGGACGGGAAGACCAC; CGTGTGGATCTGAGGGCGCTGGCTTGCGAGCTGGGCCAGGGAGGAGGAGGGTTGGGGGGC; TCCGGTGGAAACCTGCGACCCCTTCTCCTCAGCCTTCTCCTTAGCCGGTGGCCTCAGGCA; GACTCTGCCCAGAGGGGCAGCCAGGCTGCTCAGGGAAGGGGCTGAAAGCGGCAGAGGAGT; GCCCTGGCTTGGTCACCACTGGGGCCAAGGTGGGGTGGAGAGAGGCCTAGGAGCCAGAAA; GGGCCCTCTGCTGTGGTCTGAACCCCAGGGGGAGTGGGGCATTGACTCCACCCCTGTCCT; GAGCTGGAATAGGTCCTCTGGGATGCCAGCTCTCCCCTTTGTGCTTCCCTGCAGCAACCC; ATGGAGGGCCCAGGGTGCCTGGTATGGGCATCAGTTGGTGGGGGTGCGGGGGTGCGTGTC; CCCATTCCCTGCAACAGCAAATGGGGCTCCTTCTTCAGCCCTCCCCTTCCCAGCCCCAAA; CTGAGACAGACTGGGAGCTGGGAGCCTGGGGTGGACAGGACCATACCCTCTTTGAGCTTC; TGCGATGCCGGCCTTCCGTTCCTCTGGGAGGCTTGAAGTTCTGCAGAGATGTTGATATGC; CTTGCAGCTTGGACCCAATGGGTGGTGGTCAGGGCCTGGGGGCTTGGCCATGCTGGGGGA; ATGGGGCTCTGGGTTCCTGCCTGTGGCCTGTCTGTCCTCCTCCCTAATTCAGACCCAGCC; TCAAGAGGAAAGGGAGTAAAATAAAACTAACTTGTTTATAAAAAAAAAAAAAAAAAAAAA; AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA;
• Restriction Sites: Please inquire
• ACCN: NM_020435
• Insert Size: 2400 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone is found to be a perfect match to NM_020435.2.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_020435.2, NP_065168.2
• RefSeq Size: 2259 bp
• RefSeq ORF: 1320 bp
• Locus ID: 57165
• UniProt ID: Q5T442
• Cytogenetics: 1q42.13
• Protein Families: Ion Channels: Other
• Summary: This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1. [provided by RefSeq, Jul 2008]