Retinoic Acid Receptor gamma (RARG) (NM_001042728) Human Untagged Clone

SKU SC311478

RARG (untagged)-Human retinoic acid receptor, gamma (RARG), transcript variant 2

Product Data

• Type: Human Untagged Clone
• Target Symbol: Retinoic Acid Receptor gamma
• Synonyms: NR1B3; RARC
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001042728 edited; GGGGGAATCGGCTGCGGGTCCTTGGTGTTTCCAGCACCCAGTTTCCCTTCAAGCCGGGTC; GCGATGTACGACTGTATGGAAACGTTTGCCCCGGGTCCGCGACGGCTGTACGGGGCGGCC; GGGCCCGGGGCCGGCTTGCTGCGCAGAGCCACCGGCGGCTCCTGTTTCGCCGGACTTGAA; TCTTTTGCCTGGCCGCAACCCGCCAGCCTGCAATCGGTGGAGACACAGAGCACCAGCTCA; GAGGAGATGGTGCCCAGCTCGCCCTCGCCCCCTCCGCCTCCTCGGGTCTACAAGCCATGC; TTCGTGTGCAATGACAAGTCCTCTGGCTACCACTATGGGGTCAGCTCTTGTGAAGGCTGC; AAGGGCTTCTTTCGCCGAAGCATCCAGAAGAACATGGTGTACACGTGTCACCGCGACAAA; AACTGTATCATCAACAAGGTGACCAGGAATCGCTGCCAGTACTGCCGGCTACAGAAGTGC; TTCGAAGTGGGCATGTCCAAGGAAGCTGTGCGAAATGACCGGAACAAGAAGAAGAAAGAG; GTGAAGGAAGAAGGGTCACCTGACAGCTATGAGCTGAGCCCTCAGTTAGAAGAGCTCATC; ACCAAGGTCAGCAAAGCCCATCAGGAGACTTTCCCCTCGCTCTGCCAGCTGGGCAAGTAT; ACCACGAACTCCAGTGCAGACCACCGCGTGCAGCTGGATCTGGGGCTGTGGGACAAGTTC; AGTGAGCTGGCTACCAAGTGCATCATCAAGATCGTGGAGTTTGCCAAGCGGTTGCCTGGC; TTTACAGGGCTCAGCATTGCTGACCAGATCACTCTGCTCAAAGCTGCCTGCCTAGATATC; CTGATGCTGCGTATCTGCACAAGGTACACCCCAGAGCAGGACACCATGACCTTCTCCGAC; GGGCTGACCCTGAACCGGACCCAGATGCACAATGCCGGCTTCGGGCCCCTCACAGACCTT; GTCTTTGCCTTTGCTGGGCAGCTCCTGCCCCTGGAGATGGATGACACCGAGACAGGGCTG; CTCAGCGCCATCTGCCTCATCTGCGGAGACCGCATGGACCTGGAGGAGCCCGAAAAAGTG; GACAAGCTGCAGGAGCCACTGCTGGAAGCCCTGAGGCTGTACGCCCGGCGCCGGCGGCCC; AGCCAGCCCTACATGTTCCCAAGGATGCTAATGAAAATCACCGACCTCCGGGGCATCAGC; ACTAAGGGAGCTGAAAGGGCCATTACTCTGAAGATGGAGATTCCAGGCCCGATGCCTCCC; TTAATCCGAGAGATGCTGGAGAACCCTGAAATGTTTGAGGATGACTCCTCGCAGCCTGGT; CCCCACCCCAATGCCTCTAGCGAGGATGAGGTTCCTGGGGGCCAGGGCAAAGGGGGCCTG; AAGTCCCCAGCCTGACCAGGGCCCCTGACCTCCCCGCTGTGGGGGTTGGGGCTTCAGGCA; GCAGACTGACCATCTCCCAGACCGCCAGTGACTGGGGGAGGACCTGCTCTGCCCTCTCCC; CACCCCTTCCAATGAGCTCCTTGTTTTTGCCAAAGTTTCTAGGGGTGCCTCTGTGTTCAT; CCCCTTCCTGATCTAACCGGCTCCCTCGCCAGTCCCGGGGGCCTGCCCTGCTCCCACCAG; GAGAGAGGGCAAAGGGATGAGCCTGGGTTTGGACTCTAAAATCTCAGCACTGCCCCATGG; GTCCTAGACTTCCCAGGGCAAGAGGAAGACCCTGCCATTCCACAGCCCCTTCCTCTGCCA; GGTGCTTGGCTCTCTGAGAGCAAACAGGAACACTAGAGACCAAAAAGGGGACAAAGGAGA; AGGGCTGAGCCCACCTTCTTGCTCCTACCCTTGGTGCCTAATGCTGTGTGATGCACCTGC; AGGGTGTGTGCTAGCCTCTGTGCCCCGTCCTTGTGCCAGGTCAAGGTGGGGGGCAGGCTG; GGCCCTGCATTTCTGGGGCAGGAACAGAGGGTGAAAGGGACAGATAGATGCAGGTCCATT; CTGCACCTCTTGGCTCGGGTGCAGAGTTCACCCTGTGCCCTCCGTTATAAGTCCCTCCCC; CAGCCCTGTCATGTGCCTTGGGCTCCTCCTGCCCTCCATCTCAGCCATTGGGGCAGGGAC; CCTCCTACACTACAGAGGGGCCAGGGGATCCCTCTCTCCCTAGTGCCTTCCACCCTTTAC; TCCCCAGAGCAGCTTGGCCCAGGGAGGGGGGATGCTGCTTAGCTGATCCCGCCCTGACCC; AGAGGAAGCCTCTATTTATTTATTAGCTTTTGTTTACACCGTGGAATTGACCCCTTCCTC; CAGGGGTCTTGGGTGGGGGAGCCCAGGGCCCCTGTGACCCCTCCTTTCTTCCTCCAATCC; CCAGTTTGTATTTAGCTGCCAAATAAGATTCCCATTGGCTCCCTGTGTTTTCTTGGGGGG; TCAGGGTGCTGTCCCCTCCCCTCTGTTTACATCTCCCCTCTACCCCGCTGTATCGCATAT; TGCTGAGTTTTCTATTTTTGCAAAATAAAGTGATGGAAACTCAAAAAAAAAAAAAAAAAA; AAAAAAAARRRMRRMMRMTCTAGAGTATCCCTC;
• Restriction Sites: Please inquire
• ACCN: NM_001042728
• Insert Size: 2600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001042728.1.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001042728.1, NP_001036193.1
• RefSeq Size: 2740 bp
• RefSeq ORF: 1332 bp
• Locus ID: 5916
• UniProt ID: P13631
• Cytogenetics: 12q13.13
• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Summary: This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]; Transcript Variant: This variant (2) contains an alternate 5' terminal exon compared to variant 1. This results in translation initiation from an alternate start codon, and a shorter isoform (2) with a distinct N-terminus compared to isoform 1.