Kv4.3 (KCND3) (NM_004980) Human Untagged Clone

SKU SC310189

KCND3 (untagged)-Human potassium voltage-gated channel, Shal-related subfamily, member 3 (KCND3), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: Kv4.3
• Synonyms: BRGDA9; KCND3L; KCND3S; KSHIVB; KV4.3; SCA19; SCA22
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_004980 edited; GCGGGGCCCGGGCTGGCTTCGCGGAAGGGTTTGCTGAACTAACTCCAAGCTGGTGTGCCT; AGCGTCCGCGCGGCTGCCGGCCCAAGAGCTGGAGTCACCATGGCGGCCGGAGTTGCGGCC; TGGCTGCCTTTTGCCCGGGCTGCGGCCATCGGGTGGATGCCGGTGGCCAACTGCCCCATG; CCCCTGGCCCCGGCCGACAAGAACAAGCGGCAGGATGAGCTGATTGTCCTCAACGTGAGT; GGGCGGAGGTTCCAGACCTGGAGGACCACGCTGGAGCGCTACCCGGACACCCTGCTGGGC; AGCACGGAGAAGGAGTTCTTCTTCAACGAGGACACCAAGGAGTACTTCTTCGACCGGGAC; CCCGAGGTGTTCCGCTGCGTGCTCAACTTCTACCGCACGGGGAAGCTGCACTACCCGCGC; TACGAGTGCATCTCTGCCTACGACGACGAGCTGGCCTTCTACGGCATCCTCCCGGAGATC; ATCGGGGACTGCTGCTACGAGGAGTACAAGGACCGCAAGAGGGAGAACGCCGAGCGGCTC; ATGGACGACAACGACTCGGAGAACAACCAGGAGTCCATGCCCTCGCTCAGCTTCCGCCAG; ACCATGTGGCGGGCCTTCGAGAACCCCCACACCAGCACGCTGGCCCTGGTCTTCTACTAC; GTGACTGGCTTCTTCATCGCTGTCTCGGTCATCACCAACGTGGTGGAGACGGTGCCGTGC; GGCACGGTCCCGGGCAGCAAGGAGCTGCCGTGCGGGGAGCGCTACTCGGTGGCCTTCTTC; TGCCTGGACACGGCGTGCGTCATGATCTTCACCGTGGAGTACCTCCTGCGGCTCTTCGCG; GCTCCCAGCCGCTACCGCTTCATCCGCAGCGTCATGAGCATCATCGACGTGGTGGCCATC; ATGCCCTACTACATCGGTCTGGTCATGACCAACAACGAGGACGTGTCCGGCGCCTTCGTC; ACGCTCCGGGTCTTCCGCGTCTTCAGGATCTTCAAGTTTTCCCGCCACTCCCAGGGCCTG; CGGATCCTGGGCTACACACTGAAGAGCTGTGCCTCCGAACTGGGCTTTCTTCTCTTCTCC; CTCACCATGGCCATCATCATCTTTGCCACTGTGATGTTTTATGCCGAGAAGGGCTCCTCG; GCCAGCAAGTTCACAAGCATCCCTGCCTCGTTTTGGTACACCATTGTCACCATGACCACA; CTGGGATACGGAGACATGGTGCCTAAGACGATTGCAGGGAAGATCTTCGGCTCCATCTGC; TCCTTGAGTGGCGTCCTGGTCATTGCCCTGCCAGTCCCTGTGATTGTTTCCAACTTTAGC; CGGATTTACCACCAGAATCAGAGAGCTGATAAACGCAGGGCACAAAAGAAGGCCCGCCTT; GCCAGGATCCGTGTGGCCAAAACAGGCAGTTCGAATGCATACCTGCACAGCAAGCGCAAC; GGGCTCCTCAACGAGGCGCTGGAGCTGACGGGCACCCCAGAAGAGGAGCACATGGGCAAG; ACCACCTCACTCATCGAGAGCCAGCATCATCACCTGCTGCACTGCCTGGAAAAAACCACT; GGGTTGTCCTATCTTGTGGATGATCCCCTGTTATCTGTACGAACCTCCACCATCAAGAAC; CACGAGTTTATTGATGAGCAGATGTTTGAGCAGAACTGCATGGAGAGTTCAATGCAGAAC; TACCCATCCACAAGAAGTCCCTCACTGTCCAGCCACCCAGGCCTCACTACCACCTGCTGC; TCCCGTCGTAGTAAGAAGACCACACACCTGCCCAATTCTAACCTGCCAGCTACTCGCCTG; CGCAGCATGCAAGAGCTCAGCACGATCCACATCCAGGGCAGTGAGCAGCCCTCCCTCACA; ACCAGTCGCTCCAGCCTTAATTTGAAAGCAGACGACGGACTGAGACCAAACTGCAAAACA; TCCCAGATCACCACAGCCATCATCAGCATCCCCACTCCCCCAGCGCTAACCCCAGAGGGG; GAAAGTCGGCCACCCCCTGCCAGCCCAGGCCCCAACACGAACATTCCTTCCATAGCCAGC; AATGTTGTCAAGGTCTCCGCCTTGTAAAACCACTGGACAGAGGGCCAGAGTGGGTAGTGG; GGAATGAAGGGGACTGGCATGTTGGTGGGTGGTCACTGAGACCACTCCCTCCCCCCTTTC; CCCACTA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004980 unedited; NGACGTCAAATTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGCGGCGGC; TGCTGGGCGCTTCCCCGCGCTGCTGGGCGCTCGGCGCCTCCGCGGCCCCGGCTCCCGGCC; GCAGCTTCCTCGCGCGCGCGGGGCGCCGGGCGCGGGGCCCGGGCTGGCTTCGCGGAAGGG; TTTGCTGAACTAACTCCAAGCTGGTGTGCCTAGCGTCCGCGCGGCTGCCGGCCCAAGAGC; TGGAGTCACCATGGCGGCCGGAGTTGCGGCCTGGCTGCCTTTTGCCCGGGCTGCGGCCAT; CGGGTGGATGCCGGTGGCCAACTGCCCCATGCCCCTGGCCCCGGCCGACAAGAACAAGCG; GCAGGATGAGCTGATTGTCCTCAACGTGAGTGGGCGGAGGTTCCAGACCTGGAGGACCAC; GCTGGAGCGCTACCCGGACACCCTGCTGGGCAGCACGGAGAAGGAGTTCTTCTTCAACGA; GGACACCAAGGAGTACTTCTTCGACCGGGACCCCGAGGTGTTCCGCTGCGTGCTCAACTT; CTACCGCACGGGGAAGCTGCACTACCCGCGCTACGAGTGCATCTCTGCCTACGACGACGA; GCTGGCCTTCTACGGCATCCTCCCGGAGATCATCGGGGACTGCTGCTACGAGGAGTACAA; GGACCGCAAGAGGGAGAACGCCGAGCGGCTCATGGACGACAACGACTCGGAGAACAACCA; GGAGTCCATGCCCTCGCTCAGCTTCCGCCAGACCATGTTGGCGGGCCTTCGAGAACCCCC; ACACCAGCACGCTGGCCCTGGTCTTCTACTACGTGACTGGCTTCTTCATCGCTGTCTCGG; TCATCACCAACGTGGTGGGAGACGGTGCCGTGCGGCACGGTCC;
• Restriction Sites: Please inquire
• ACCN: NM_004980
• Insert Size: 2200 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004980.3, NP_004971.2
• RefSeq Size: 2693 bp
• RefSeq ORF: 1968 bp
• Locus ID: 3752
• UniProt ID: Q9UK17
• Cytogenetics: 1p13.2
• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane
• Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (1), also known as the long splice variant, encodes the longer isoform (1).