Senataxin (SETX) (NM_015046) Human Untagged Clone
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | Senataxin |
| Synonyms | ALS4; AOA2; bA479K20.2; SCAN2; SCAR1; Sen1 |
| Vector | pCMV6 series |
| Sequence Data |
Fully Sequenced ORF
>NCBI ORF sequence for NM_015046, the custom clone sequence may differ by one or more nucleotides
ATGAGCACATGTTGTTGGTGTACGCCAGGTGGTGCTTCCACCATTGACTTCCTAAAGCGC TATGCTTCCAACACTCCGTCCGGTGAATTTCAAACAGCCGACGAAGACCTCTGCTACTGC TTGGAGTGTGTGGCTGAGTACCACAAAGCAAGAGATGAATTGCCATTCTTGCATGAGGTT TTATGGGAATTAGAAACCTTACGTCTCATAAATCACTTTGAAAAATCCATGAAGGCAGAA ATTGGAGATGATGATGAGTTATATATAGTAGACAATAATGGAGAGATGCCACTGTTTGAC ATCACTGGGCAAGACTTTGAAAATAAGCTTCGAGTTCCTCTTCTTGAAATACTGAAATAT CCTTACTTGCTTCTACATGAACGTGTTAACGAGTTATGTGTTGAAGCACTTTGTCGGATG GAACAAGCCAATTGCTCCTTTCAGGTGTTTGATAAACATCCAGGGATCTATTTGTTTTTA GTCCATCCCAATGAAATGGTTCGGCGTTGGGCTATCTTGACTGCAAGAAACTTGGGGAAA GTGGACAGAGATGATTATTATGACTTACAAGAAGTTTTACTTTGCCTTTTTAAAGTCATT GAGTTGGGGCTTTTAGAGAGTCCAGACATTTATACTTCTTCTGTCCTAGAGAAGGGTAAA CTGATTCTTCTGCCCTCACACATGTATGATACTACCAACTACAAAAGCTATTGGTTAGGT ATTTGCATGTTGCTGACCATTCTTGAGGAACAAGCCATGGATTCCCTGTTGTTGGGCTCA GACAAACAAAATGATTTTATGCAATCGATACTTCACACTATGGAGAGGGAAGCAGATGAT GATAGTGTGGATCCTTTCTGGCCAGCGTTACACTGTTTTATGGTGATTCTGGATCGCCTT GGATCTAAGGTCTGGGGTCAACTTATGGATCCTATTGTGGCATTTCAAACCATTATCAAC AACGCAAGCTACAATAGAGAGATCCGACATATACGGAACAGCTCTGTAAGGACCAAGTTA GAACCGGAGTCCTATTTGGATGATATGGTGACTTGCAGCCAGATCGTATACAATTATAAT CCTGAAAAGACCAAAAAGGATTCTGGATGGAGAACAGCCATTTGCCCAGATTATTGTCCT AACATGTATGAAGAAATGGAAACATTAGCCAGTGTACTTCAGTCAGATATTGGTCAAGAC ATGCGTGTTCATAACAGCACATTTCTATGGTTCATCCCTTTTGTCCAGTCCCTCATGGAT CTTAAGGATTTGGGTGTGGCTTACATAGCACAGGTTGTTAATCATCTGTACTCTGAAGTC AAAGAAGTCCTCAACCAAACAGATGCTGTGTGTGACAAAGTCACTGAATTTTTTCTTCTA ATTTTGGTATCAGTGATTGAACTGCATAGAAATAAAAAATGTTTGCATTTGCTGTGGGTA AGTTCCCAGCAATGGGTGGAAGCCGTCGTCAAATGTGCCAAGCTTCCTACCACTGCGTTT ACACGGAGTTCTGAGAAATCATCTGGAAATTGCTCCAAAGGAACAGCAATGATATCTTCA CTGTCATTGCATTCCATGCCATCTAACTCTGTACAACTTGCTTATGTGCAGCTGATTAGA AGTCTCCTTAAAGAAGGTTATCAGCTTGGGCAGCAGTCTCTTTGCAAGCGATTCTGGGAT AAGCTCAACTTATTCCTTAGAGGAAATTTATCTCTAGGTTGGCAGTTGACTAGTCAGGAA ACCCATGAGCTACAAAGTTGCTTAAAGCAAATTATTAGAAACATAAAATTCAAAGCACCT CCATGTAACACTTTTGTGGATCTGACTTCTGCATGTAAAATCTCTCCTGCATCTTATAAT AAAGAAGAAAGTGAACAAATGGGGAAGACGTCTAGAAAAGATATGCATTGTTTGGAAGCT TCCAGCCCAACATTTTCTAAAGAACCAATGAAAGTGCAAGACAGTGTATTGATCAAAGCA GATAACACTATAGAAGGTGACAATAATGAGCAAAATTATATAAAGGATGTGAAACTAGAG GACCATCTCTTAGCTGGGTCATGCTTAAAGCAGAGTAGTAAAAACATTTTTACTGAAAGA GCTGAAGATCAAATTAAAATAAGTACAAGGAAGCAGAAGTCTGTAAAAGAGATCTCTTCA TATACACCAAAGGACTGTACTTCAAGAAATGGTCCAGAAAGGGGATGTGACAGAGGAATA ATAGTATCAACACGTTTGTTGACTGATTCTAGCACTGATGCTTTGGAAAAAGTGTCCACA TCGAATGAAGATTTCTCTTTAAAGGATGATGCTCTTGCTAAAACCTCAAAACGAAAAACT AAGGTACAGAAAGATGAAATCTGTGCAAAGTTATCACATGTAATAAAGAAGCAACACAGG AAGAGTACTTTGGTCGATAATACTATCAATTTAGATGAAAATTTGACTGTATCTAACATT GAGAGTTTCTATTCAAGGAAAGATACAGGAGTTCAGAAAGGAGATGGTTTCATACACAAT CTTTCTTTAGACCCTAGTGGTGTTCTGGATGATAAGAATGGAGAACAAAAATCTCAAAAC AATGTATTGCCAAAAGAGAAACAATTAAAGAATGAAGAATTAGTTATTTTCTCTTTCCAT GAAAACAATTGTAAAATACAGGAATTTCATGTTGATGGTAAAGAATTGATCCCTTTTACA GAAATGACCAATGCTTCAGAGAAGAAATCATCTCCCTTTAAAGATCTTATGACTGTACCT GAATCAAGAGATGAGGAGATGAGTAATAGTACCAGTGTGATTTATTCTAACTTGACAAGA GAACAGGCCCCTGACATCAGTCCTAAATCTGACACCTTAACGGATTCTCAGATAGACAGA GACCTTCACAAATTATCTTTACTAGCTCAAGCCAGTGTTATTACGTTCCCATCCGATTCA CCTCAGAACTCATCGCAGCTGCAAAGGAAAGTAAAAGAAGATAAAAGATGTTTCACAGCT AACCAAAATAATGTTGGAGATACCTCCCGTGGACAGGTTATTATTATTTCAGATTCTGAT GATGATGATGATGAAAGAATCCTGAGTCTTGAGAAACTCACTAAACAGGACAAAATATGC CTTGAGAGGGAACATCCAGAGCAGCACGTTTCAACAGTTAATAGTAAGGAGGAAAAGAAT CCAGTAAAGGAAGAAAAGACAGAGACTCTTTTTCAGTTTGAGGAATCTGATTCTCAGTGT TTTGAGTTTGAAAGTTCATCTGAAGTGTTTTCAGTTTGGCAAGATCATCCAGACGATAAT AATTCAGTTCAAGATGGTGAGAAAAAATGTTTGGCTCCTATAGCCAATACTACAAATGGT CAGGGTTGTACAGATTATGTATCTGAAGTTGTTAAAAAAGGAGCAGAGGGCATTGAAGAA CACACAAGACCACGGAGTATTTCTGTTGAAGAATTTTGTGAAATTGAAGTAAAAAAGCCT AAGAGAAAACGATCTGAAAAACCAATGGCTGAAGATCCTGTGAGGCCTTCATCTTCTGTC AGAAATGAGGGCCAGTCTGATACTAATAAGAGAGATCTTGTGGGAAATGATTTTAAAAGT ATTGATAGAAGGACTTCAACTCCCAATTCACGTATTCAGAGAGCCACTACGGTTTCACAA AAGAAGTCTTCAAAGCTTTGTACTTGTACAGAACCCATCAGGAAAGTTCCAGTTTCTAAG ACCCCTAAGAAAACTCATTCAGATGCCAAAAAAGGACAGAATAGAAGTTCAAATTACCTA AGTTGTAGAACAACTCCTGCTATAGTGCCGCCAAAGAAATTTCGTCAGTGTCCTGAGCCA ACTTCAACAGCTGAGAAACTTGGCCTGAAAAAGGGTCCTCGTAAGGCATATGAGTTGTCC CAGCGGTCTTTGGATTATGTAGCTCAATTACGTGATCATGGCAAAACTGTTGGAGTAGTT GATACCCGAAAAAAGACTAAATTAATTTCTCCTCAGAACCTGTCTGTCAGAAATAATAAG AAACTTCTGACTAGTCAAGAACTTCAGATGCAAAGGCAGATCAGACCCAAATCACAAAAA AATAGACGAAGACTTTCTGATTGTGAAAGTACAGATGTTAAAAGAGCAGGGTCACATACA GCACAGAATTCTGACATATTTGTACCAGAATCTGATAGGTCAGATTATAATTGTACAGGA GGAACTGAGGTACTTGCCAACAGTAACAGAAAACAGTTAATAAAATGCATGCCTTCTGAA CCAGAAACCATAAAAGCAAAACATGGGTCTCCAGCAACTGATGATGCTTGCCCTTTGAAC CAGTGTGATTCTGTAGTGTTAAATGGAACAGTACCAACAAATGAAGTAATTGTCTCCACT TCAGAAGACCCTCTGGGTGGAGGTGATCCAACAGCACGTCATATAGAGATGGCAGCTTTG AAAGAAGGAGAGCCTGACTCCAGCAGTGATGCAGAGGAAGATAACTTATTTTTAACCCAA AATGATCCTGAAGATATGGATTTATGTTCACAAATGGAGAATGACAATTATAAACTCATT GAACTAATTCATGGAAAAGATACAGTTGAGGTTGAAGAAGATTCTGTAAGTCGGCCTCAG TTGGAATCTTTGAGTGGCACAAAGTGTAAGTACAAAGATTGTCTTGAAACCACAAAAAAC CAGGGTGAATACTGCCCAAAACACTCTGAAGTGAAAGCAGCAGATGAAGATGTATTTCGT AAACCTGGCTTGCCTCCTCCTGCATCTAAACCTTTGAGACCTACCACTAAGATTTTTAGC TCAAAGAGTACTTCACGAATTGCTGGTCTTTCTAAATCTTTGGAAACTTCTTCAGCACTT TCACCGTCTCTAAAAAATAAGTCAAAGGGGATACAGTCGATTTTGAAAGTACCACAGCCA GTTCCCCTCATAGCTCAGAAGCCAGTTGGTGAAATGAAGAATTCGTGCAATGTTCTTCAT CCTCAGTCTCCGAATAATTCCAACAGGCAAGGTTGCAAAGTTCCATTTGGTGAAAGCAAA TATTTTCCATCTTCCTCTCCAGTAAACATTCTTTTGTCATCACAGTCTGTCTCTGACACC TTCGTTAAAGAGGTCTTAAAATGGAAATATGAAATGTTTTTGAACTTTGGTCAGTGTGGG CCCCCTGCAAGTCTTTGTCAGTCCATCTCAAGACCTGTGCCTGTCAGATTTCACAATTAT GGAGATTATTTTAATGTTTTTTTCCCTTTGATGGTATTGAATACTTTTGAAACAGTGGCA CAAGAATGGCTCAACTCTCCAAATAGAGAGAATTTCTATCAGTTGCAAGTACGAAAATTT CCTGCCGATTATATAAAATACTGGGAGTTTGCAGTTTATCTGGAAGAATGTGAACTGGCT AAACAGCTTTATCCAAAGGAAAACGATTTGGTGTTTTTAGCTCCTGAGAGAATAAATGAA GAGAAGAAAGATACAGAGAGAAATGACATACAAGATCTCCACGAATATCATTCTGGTTAT GTTCATAAATTTCGCCGCACGTCAGTCATGCGTAATGGGAAAACTGAGTGTTACCTTTCC ATCCAGACTCAAGAGAACTTTCCGGCCAATTTAAACGAACTTGTGAATTGTATTGTAATC AGTTCTCTGGTAACTACACAAAGGAAGTTGAAAGCCATGTCTCTGTTGGGTAGTCGGAAC CAACTGGCTAGAGCTGTTCTGAATCCAAACCCTATGGACTTCTGTACAAAAGATTTACTG ACTACAACATCTGAGAGAATTATTGCGTACTTAAGAGATTTCAATGAAGATCAAAAGAAA GCAATAGAAACTGCATATGCTATGGTGAAACACTCACCATCAGTTGCCAAAATCTGCTTG ATTCATGGACCACCTGGAACAGGAAAATCAAAAACTATTGTTGGCCTCCTCTATCGTCTA CTGACAGAGAACCAGAGGAAGGGGCATTCAGACGAAAACTCCAATGCCAAAATCAAACAA AACCGTGTCCTCGTGTGTGCACCTTCCAATGCAGCTGTTGATGAACTCATGAAAAAAATT ATCCTTGAATTCAAAGAAAAATGTAAAGACAAGAAGAATCCTTTAGGAAACTGTGGAGAT ATAAATTTAGTACGACTGGGTCCAGAAAAGTCTATTAATAGTGAGGTTCTAAAGTTCAGT TTGGACAGCCAAGTAAACCACAGAATGAAAAAAGAGTTACCTTCTCATGTTCAGGCGATG CATAAAAGAAAGGAATTTCTAGATTATCAGCTGGATGAGCTTTCCCGGCAGCGAGCTCTA TGCCGAGGTGGACGGGAAATACAGAGGCAAGAATTAGATGAAAACATTTCCAAAGTTTCT AAGGAAAGGCAGGAACTTGCTTCTAAAATTAAAGAGGTTCAAGGACGCCCACAGAAAACA CAGAGTATCATCATCTTAGAGTCCCATATCATCTGCTGCACGTTGAGCACAAGTGGTGGT TTACTACTTGAGTCTGCTTTCCGTGGGCAAGGGGGTGTCCCCTTCAGCTGTGTCATTGTT GATGAGGCTGGACAGTCTTGTGAAATTGAGACTCTTACTCCACTCATCCATCGCTGCAAT AAGCTCATCCTAGTAGGAGATCCTAAGCAGCTCCCTCCGACAGTCATCTCTATGAAAGCA CAGGAGTATGGCTACGACCAGTCAATGATGGCTCGCTTCTGCAGACTGCTGGAAGAGAAT GTAGAACACAACATGATCAGCAGGCTGCCCATTCTACAGCTCACTGTTCAGTACAGGATG CATCCAGACATATGCCTCTTCCCTTCTAATTATGTTTATAACAGAAACTTAAAAACAAAT AGACAGACAGAAGCCATTCGATGTTCATCAGATTGGCCATTTCAGCCATACCTTGTGTTT GATGTTGGAGATGGTTCAGAAAGACGGGATAATGACTCATATATAAATGTTCAAGAAATA AAACTGGTGATGGAAATAATTAAGCTTATTAAAGACAAAAGAAAGGATGTTAGTTTTCGA AACATTGGCATAATAACTCATTACAAGGCCCAGAAGACGATGATTCAGAAGGATTTGGAC AAAGAGTTCGATAGAAAAGGACCAGCAGAAGTAGACACTGTGGATGCATTCCAGGGTCGG CAGAAGGATTGTGTTATTGTTACGTGTGTCAGAGCAAATAGCATCCAAGGTTCAATTGGA TTCCTGGCAAGTTTGCAGAGATTGAATGTCACCATCACACGAGCCAAGTACAGCCTCTTC ATCCTCGGACATTTGAGGACCCTGATGGAAAACCAGCATTGGAATCAGCTGATTCAGGAT GCTCAGAAGCGTGGTGCCATTATTAAGACCTGTGACAAAAACTATAGACATGATGCAGTG AAGATTCTGAAACTCAAGCCTGTGCTGCAGAGAAGTCTCACTCACCCTCCTACCATAGCC CCAGAGGGGTCCAGACCCCAGGGTGGTTTGCCCAGCAGCAAGCTAGACAGTGGATTTGCC AAGACATCTGTTGCTGCTTCTCTATACCACACACCCTCTGACTCCAAGGAAATTACTCTT ACTGTTACTTCAAAGGACCCTGAAAGACCTCCTGTTCATGACCAACTTCAGGACCCACGA CTGCTGAAGAGGATGGGCATTGAGGTCAAAGGAGGAATATTCCTTTGGGATCCACAACCC TCGAGCCCCCAGCATCCTGGAGCAACACCTCCTACGGGCGAGCCGGGCTTCCCTGTCGTT CACCAGGACCTGAGCCATATACAGCAGCCCGCTGCTGTAGTGGCTGCTCTGAGCAGCCAC AAACCTCCCGTGCGGGGCGAACCTCCAGCTGCCAGTCCCGAGGCTTCCACGTGTCAGAGC AAATGTGATGACCCGGAAGAGGAGCTCTGTCACAGGAGAGAGGCCAGGGCTTTCAGTGAA GGGGAGCAGGAGAAGTGTGGTTCCGAGACCCATCACACCAGGAGGAACTCTAGGTGGGAC AAGAGGACACTGGAGCAGGAGGACAGCAGTTCCAAGAAAAGAAAGCTTTTATAG |
| Restriction Sites | Please inquire |
| ACCN | NM_015046 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_015046.4, NP_055861.2 |
| RefSeq Size | 8583 bp |
| RefSeq ORF | 8034 bp |
| Locus ID | 23064 |
| UniProt ID | Q7Z333 |
| Cytogenetics | 9q34.13 |
| Summary | This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4). [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the shortest transcript and encodes the shorter isoform (1). Variants 1 and 2 encode the same isoform (1). |
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