Aurora C (AURKC) (NM_001015878) Human Untagged Clone

SKU SC302003

AURKC (untagged)-Human aurora kinase C (AURKC), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: Aurora C
• Synonyms: AIE2; AIK3; ARK3; AurC; aurora-C; HEL-S-90; SPGF5; STK13
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_001015878 edited; ATGAGCTCCCCCAGAGCTGTGGTGCAGCTGGGCAAAGCTCAACCTGCAGGCGAAGAGTTG; GCTACAGCAAACCAAACAGCCCAGCAGCCCAGCAGCCCAGCCATGCGGCGCCTCACAGTC; GATGACTTTGAAATCGGGCGTCCCCTGGGCAAGGGGAAATTTGGGAATGTGTACCTGGCT; CGGCTCAAGGAAAGCCATTTCATTGTGGCCCTGAAGGTTCTCTTCAAGTCGCAGATAGAG; AAGGAAGGACTGGAGCACCAGCTGCGCCGGGAAATTGAGATCCAGGCTCATCTACAACAC; CCCAATATCCTGCGCCTGTATAACTATTTCCATGATGCACGCCGGGTGTACCTGATTCTG; GAATATGCTCCAAGGGGTGAGCTCTACAAGGAGCTGCAGAAAAGCGAGAAATTAGATGAA; CAGCGCACAGCCACGATAATAGAGGAGTTGGCAGATGCCCTGACCTACTGCCATGACAAG; AAAGTGATTCACAGAGATATTAAGCCAGAGAACCTGCTGCTGGGGTTCAGGGGTGAGGTG; AAGATTGCAGATTTTGGCTGGTCTGTGCACACCCCCTCCCTGAGGAGGAAGACAATGTGT; GGGACACTGGACTACTTGCCGCCAGAAATGATTGAGGGGAGAACATATGATGAAAAGGTG; GATTTGTGGTGCATTGGAGTGCTCTGCTATGAGCTGCTGGTGGGATATCCACCCTTTGAG; AGCGCCTCCCACAGTGAGACTTACAGACGCATCCTCAAGGTAGATGTGAGGTTTCCACTA; TCAATGCCTCTGGGGGCCCGGGACTTGATTTCCAGGCTTCTCAGATACCAGCCCTTGGAG; AGACTGCCCCTGGCCCAGATCCTGAAGCACCCCTGGGTTCAGGCCCACTCCCGAAGGGTG; CTGCCTCCCTGTGCTCAGATGGCTTCCTGAGCCCTGTCTGCCTCTGTTCCCTTTGTGTGT; GTTCAGGGAGCTCTCCTGGCTCTGCCACCTCATTTGTCTTTATTTTTTTCTCTTTTAAGA; TGTAAGATGCTAATTAATAAAAGCTGAATCATTTCATACCAGCAAAAAAAAAAAAAAAAA; ACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCTGAA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001015878 unedited; CGCCAGCATTTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGATGAGCTC; CCCCANAGCTGTGGTGCAGCTGGGCAAAGCTCAACCTGCAGGCGAAGAGTTGGCTACAGC; AAACCAAACAGCCCAGCAGCCCAGCAGCCCAGCCATGCGGCGCCTCACAGTCGATGACTT; TGAAATCGGGCGTCCCCTGGGCAAGGGGAAATTTGGGAATGTGTACCTGGCTCGGCTCAA; GGAAAGCCATTTCATTGTGGCCCTGAAGGTTCTCTTCAAGTCGCAGATAGAGAAGGAAGG; ACTGGAGCACCAGCTGCGCCGGGAAATTGAGATCCAGGCTCATCTACAACACCCCAATAT; CCTGCGCCTGTATAACTATTTCCATGATGCACGCCGGGTGTACCTGATTCTGGAATATGC; TCCAAGGGGTGAGCTCTACAAGGAGCTGCAGAAAAGCGAGAAATTAGATGAACAGCGCAC; AGCCACGATAATAGAGGAGTTGGCAGATGCCCTGACCTACTGCCATGACAAGAAAGTGAT; TCACAGAGATATTAAGCCAGAGAACCTGCTGCTGGGGTTCAGGGGTGAGGTGAAGATTGC; AGATTTTGGCTGGTCTGTGCACACCCCCTCCCTGAGGAGGAAGACAATGTGTGGGACACT; GGACTACTTGCCGCCAGAAATGATTGAGGGGAGAACATATGATGAAAAGGTGGATTTGTG; GTGCATTGGAGTGCTCTGCTATGAGCTGCTGGTGGGATATCCACCCTTTGAGAGCGCCTC; CCACAGTGAGACTTACAGACGCATCCTCAAGG;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001015878 unedited; CCATCGGGGATGGCACTTCCGGGNCCAGNGNGAGCACTGGGGNGGGGTCACAGGGNTGCC; ACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTT; TTTTTTTTTTTTGCTGGTATGAAATGATTCAGCTTTTATTAATTAGCATCTTACATCTTA; AAAGAGAAAAAAATAAAGACAAATGAGGTGGCAGAGCCAGGAGAGCTCCCTGAACACACA; CAAAGGGAACAGAGGCAGACAGGGCTCAGGAAGCCATCTGAGCACAGGGAGGCAGCACCC; TTCGGGAGTGGGCCTGAACCCAGGGGTGCTTCAGGATCTGGGCCAGGGGCAGTCTCTCCA; AGGGCTGGTATCTGAGAAGCCTGGAAATCAAGTCCCGGGCCCCCAGAGGCATTGATAGTG; GAAACCTCACATCTACCTTGAGGATGCGTCTGTAAGTCTCACTGTGGGAGGCGCTCTCAA; AGGGTGGATATCCCACCAGCAGCTCATAGCAGAGCACTCCAATGCACCACAAATCCACCT; TTTCATCATATGTTCTCCCCTCAATCATTTCTGGCGGCAAGTAGTCCAGTGTCCCACACA; TTGTCTTCCTCCTCAGGGAGGGGGTGTGCACAGACCAGCCAAAATCTGCAATCTTCACCT; CACCCCTGAACCCCAGCAGCAGGTTCTCTGGCTTAATATCTCTGTGAATCACTTTCTTGT; CATGGCAGTAGGTCAGGGCATCTGCCAACTCCTCTATTATCGTGGCTGTGCGCTGTTCAT; CTAATTTCTCGCTTTTCTGCAGCTCCCTGTAAAGCTCACCCCTTTGGAGCT;
• Restriction Sites: Please inquire
• ACCN: NM_001015878
• Insert Size: 1100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001015878.1, NP_001015878.1
• RefSeq Size: 1261 bp
• RefSeq ORF: 930 bp
• Locus ID: 6795
• UniProt ID: Q9UQB9
• Cytogenetics: 19q13.43
• Protein Families: Druggable Genome, Protein Kinase
• Summary: This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (1) encodes the longest isoform (1).