SLITRK4 (NM_173078) Human Untagged Clone

SKU SC128227

SLITRK4 (untagged)-Human SLIT and NTRK-like family, member 4 (SLITRK4), transcript variant 2

Product Data

• Type: Human Untagged Clone
• Target Symbol: SLITRK4
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC128227 sequence for NM_173078 edited (data generated by NextGen Sequencing); ATGTTTCTGTGGCTGTTTCTGATTTTGTCAGCCCTGATTTCTTCGACAAATGCAGATTCT; GACATATCGGTGGAAATTTGCAATGTGTGTTCCTGCGTGTCAGTTGAGAATGTGCTCTAT; GTCAACTGTGAGAAGGTTTCAGTCTACAGACCAAATCAGCTGAAACCACCTTGGTCTAAT; TTTTATCACCTCAATTTCCAAAATAATTTTTTAAATATTCTGTATCCAAATACATTCTTG; AATTTTTCACATGCAGTCTCCCTGCATCTGGGGAATAATAAACTGCAGAACATTGAGGGA; GGAGCCTTTCTTGGGCTCAGTGCATTAAAGCAGTTGCACTTGAACAACAATGAATTAAAG; ATTCTCCGAGCTGACACTTTCCTTGGCATAGAGAACTTGGAGTATCTCCAGGCTGACTAC; AATTTAATCAAGTATATTGAACGAGGAGCCTTCAATAAGCTCCACAAACTGAAAGTTCTC; ATTCTTAATGACAATCTGATTTTATTCCTTCCTGATAATATTTTCCGATTCGCATCTTTG; ACCCATCTGGATATACGAGGGAACAGAATCCAGAAGCTCCCTTATATCGGGGTTCTGGAA; CACATTGGCCGTGTCGTTGAATTGCAACTGGAAGATAACCCTTGGAACTGTAGCTGTGAT; TTATTGCCCTTAAAAGCTTGGCTGGAGAACATGCCATATAACATTTACATAGGAGAAGCT; ATCTGTGAAACTCCCAGTGACTTATATGGAAGGCTTTTAAAAGAAACCAACAAACAAGAG; CTATGTCCCATGGGCACCGGCAGTGATTTTGACGTGCGCATCCTGCCTCCATCTCAGCTG; GAAAATGGCTACACCACTCCCAATGGTCACACTACCCAAACATCTTTACACAGATTAGTA; ACTAAACCACCAAAAACAACAAATCCTTCCAAGATCTCTGGAATCGTTGCAGGCAAAGCC; CTCTCCAACCGCAATCTCAGTCAGATTGTGTCTTACCAAACAAGGGTGCCTCCTCTAACA; CCTTGCCCGGCACCTTGCTTCTGCAAAACACACCCTTCAGATTTGGGACTAAGTGTGAAC; TGCCAAGAGAAAAATATACAGTCTATGTCTGAACTGATACCGAAACCTTTAAATGCGAAG; AAGCTGCACGTCAATGGCAATAGCATCAAGGATGTGGACGTATCAGACTTCACTGACTTT; GAAGGACTGGATTTGCTTCATTTAGGCAGCAATCAAATTACAGTGATTAAGGGAGACGTA; TTTCACAATCTCACTAATTTACGCAGGCTATATCTCAATGGCAATCAAATTGAGAGACTC; TATCCTGAAATATTTTCAGGTCTTCATAACCTGCAGTATCTGTATTTGGAATACAATTTG; ATTAAGGAAATCTCAGCAGGCACCTTTGACTCCATGCCAAATTTGCAGTTACTGTACTTA; AACAATAATCTCCTAAAGAGCCTGCCTGTTTACATCTTTTCCGGAGCACCCTTAGCTAGA; CTGAACCTGAGGAACAACAAATTCATGTACCTGCCTGTCAGTGGGGTCCTTGATCAGTTG; CAATCTCTTACACAGATTGACTTGGAGGGCAACCCATGGGACTGTACTTGTGACTTGGTG; GCATTAAAGCTGTGGGTGGAGAAGTTGAGCGACGGGATTGTTGTGAAAGAACTGAAATGT; GAGACGCCTGTTCAGTTTGCCAACATTGAACTGAAGTCCCTCAAAAATGAAATCTTATGT; CCCAAACTTTTAAATAAGCCGTCTGCACCATTCACAAGCCCTGCACCTGCCATTACATTC; ACCACTCCTTTGGGTCCCATTCGAAGTCCTCCTGGTGGGCCAGTGCCTCTGTCTATTTTA; ATCTTAAGTATCTTAGTGGTCCTCATTTTAACGGTGTTTGTTGCTTTTTGCCTTCTTGTT; TTTGTCCTGCGACGCAACAAGAAACCCACAGTGAAGCACGAAGGCCTGGGGAATCCTGAC; TGTGGCTCCATGCAGCTGCAGCTAAGGAAGCATGACCACAAAACCAATAAAAAAGATGGA; CTGAGCACAGAAGCTTTCATTCCACAAACTATAGAACAGATGAGCAAGAGCCACACTTGT; GGCTTGAAAGAGTCAGAAACTGGGTTCATGTTTTCAGATCCTCCAGGACAGAAAGTTGTT; ATGAGAAATGTGGCCGACAAGGAGAAAGATTTATTACATGTAGATACCAGGAAGAGACTG; AGCACAATTGATGAGCTGGATGAATTATTCCCTAGCAGGGATTCCAATGTGTTTATTCAG; AATTTTCTTGAAAGCAAAAAGGAGTATAATAGCATAGGTGTCAGTGGCTTTGAGATCCGC; TATCCAGAAAAACAACCAGACAAAAAAAGTAAGAAGTCACTGATAGGTGGCAACCACAGT; AAAATTGTTGTGGAACAAAGGAAGAGTGAGTATTTTGAACTGAAGGCGAAACTGCAGAGT; TCCCCTGACTACCTACAGGTCCTTGAGGAGCAAACAGCTTTGAACAAGATCTAG; ; Clone variation with respect to NM_173078.3; 503 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_173078 unedited; GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGAGGAGCTCTGTCCGGAA; TCACATAGATACCATCGTGGAAACAGCAGCGCAGGTCACGGCGCCGCGGGCCCTGCACCA; GACGCTGGGCTCTAGAGATTATTTCTCTTTATTCAGAAGCATACAGTTGTTTGCTGATTG; CAAGAAGATGTTTCTGTGGCTGTTTCTGATTTTGTCAGCCCTGATTTCTTCGACAAATGC; AGATTCTGACATATCGGTGGAAATTTGCAATGTGTGTTCCTGCGTGTCAGTTGAGAATGT; GCTCTATGTCAACTGTGAGAAGGTTTCAGTCTACAGACCAAATCAGCTGAAACCACCTTG; GTCTAATTTTTATCACCTCAATTTCCAAAATAATTTTTTAAATATTCTGTATCCAAATAC; ATTCTTGAATTTTTCACATGCAGTCTCCCTGCATCTGGGGAATAATAAACTGCAGAACAT; TGAGGGAGGAGCCTTTCTTGGGCTCAGTGCATTAAAGCAGTTGCACTTGAACAACAATGA; ATTAAAGATTCTCCGAGCTGACACTTTCCTTGGCATAGAGAACTTGGAGTATCTCCAGGC; TGACTACAATTTAATCAAGTATATTGAACGAGGAGCCTTCAATAAGCTCCACAAACTGAA; AGTTCTCATTCTTAATGANCATCTGATTTTATTCCTTCCTGNATATATTTTCCGATTCGC; ATCTTTGACCCATCTGGATATACGANGGAACAGATCCAGAAGCTCCTTATAATCGGGTTC; TGGACACATTNGNCCGTGTCGTTGAATTGCACTGGAAAGATACCCTTGNACTGTAGCTGT; GATTTATTGCCCTTAAAGCTGGCTGGAGACATGCCATATACATTACTANGAGAGCT;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_173078 unedited; TTTACACGGGAGTTGTTACAATGCCACAAATCAAAGGATTATTCCAGTTCCACCAACTTA; ATCTACGTGCAAGATAAAGGACCCAGCTGGTACAGGTGTACCAGTTTTCTTGAGTTTGCT; TTACAAAGCACAAAGAGACGAAGGTTTTGCATTGGAGTACAAAACAGATTTGCCTCTTGA; GGTTAAATTCAGTATTATGTGTATAAAGCATCCCTTTGGCAATAGAGTTTGCAGTATCCC; CACAGGACTCCACAGTATAGGTTTTATGTAGTAAAATCTATTAAACAAATTCTCTTCTAC; TTGACACATCTTTGCAGCTACAGTTAATGAGACACCCTTGGAAACACCTGCCTCCATGCC; TATTGATAATATAGTATTTGGAAGTTAGAAGTCAACAAAAGGCACTTTCATCATTAAATA; AATGTCCTCTGTATGAAGTAAGATTACATGACCTAGATCTTGTTCAAAGCTGTTTGCTCC; TCAAGGACCTGTAGGTAGTCAGGGGAACTCTGCAGTTTCGCCTTCAGTTCAAAATACTCA; CTCTTCCTTTGTTCCACAACAATTTTACTGTGGTTGCCACCTATCAGTGACTTCTTACTT; TTTTTGTCTGGTTGTTTTTCTGGATAGCGGATCTCNAAGCCACTGACACCTATGCTATTA; TACTCCTTTTTGCTTTTCAGAAAATTCTGAATAACACATTGGAATCCCTGCTAGGGAATA; AATTCTCCAGCTCATCAATTGGGCTCCATCTCCTCCGGTATCTAACTGTAATAAAACCTT; CTCCTTGTCGGCCACATTTCCTCATAAACCTTTCTGTTCGGGGGGATCCTGAAACTTGAA; CCCAGTTTCTGGCTCTTTTAGGCCAAAGTGTGG;
• Restriction Sites: NotI-NotI
• ACCN: NM_173078
• Insert Size: 3700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_173078.2, NP_775101.1
• RefSeq Size: 3383 bp
• RefSeq ORF: 2514 bp
• Locus ID: 139065
• UniProt ID: Q8IW52
• Cytogenetics: Xq27.3
• Domains: LRR, LRRCT, LRRNT, LRR_PS, LRR_SD22, LRR_TYP
• Protein Families: Transmembrane
• Summary: This gene encodes a transmembrane protein belonging to the the SLITRK family. These family members include two N-terminal leucine-rich repeat domains similar to those found in the axonal growth-controlling protein SLIT, as well as C-terminal regions similar to neurotrophin receptors. Studies of an homologous protein in mouse suggest that this family member functions to suppress neurite outgrowth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]; Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.