SESN2 (NM_031459) Human Untagged Clone

SKU SC128085

SESN2 (untagged)-Human sestrin 2 (SESN2)

Product Data

• Type: Human Untagged Clone
• Target Symbol: SESN2
• Synonyms: HI95; SES2; SEST2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC128085 sequence for NM_031459 edited (data generated by NextGen Sequencing); ATGATCGTGGCGGACTCCGAGTGCCGCGCAGAGCTCAAAGACTACCTGCGGTTCGCCCCG; GGCGGCGTCGGCGACTCGGGCCCCGGAGAGGAGCAGAGGGAGAGCCGGGCTCGGCGAGGC; CCTCGAGGGCCCAGCGCCTTCATCCCCGTGGAGGAGGTCCTTCGGGAGGGGGCTGAGAGC; CTCGAGCAGCACCTGGGGCTGGAGGCACTGATGTCCTCTGGGCGAGTAGACAACCTGGCA; GTGGTGATGGGCCTGCACCCTGACTACTTTACCAGCTTCTGGCGCCTGCACTACCTGCTG; CTGCACACGGATGGTCCCTTGGCCAGCTCCTGGCGCCACTACATTGCCATCATGGCTGCC; GCCCGCCATCAGTGTTCTTACCTGGTAGGCTCCCACATGGCCGAGTTTCTGCAGACTGGT; GGTGACCCTGAGTGGCTGCTGGGCCTCCACCGGGCCCCCGAGAAGCTGCGCAAACTCAGC; GAGATCAACAAGTTGCTGGCGCATCGGCCATGGCTCATCACCAAGGAACACATCCAGGCC; TTGCTGAAGACCGGCGAGCACACTTGGTCCCTGGCCGAGCTCATTCAGGCTCTGGTCCTG; CTCACCCACTGCCACTCGCTCTCCTCCTTCGTGTTTGGCTGTGGCATCCTCCCTGAGGGG; GATGCAGATGGCAGCCCTGCCCCCCAGGCACCTACACCCCCTAGTGAACAGAGCAGCCCC; CCAAGCAGGGACCCGTTGAACAACTCTGGGGGCTTTGAGTCTGCCCGCGACGTGGAGGCG; CTGATGGAGCGCATGCAGCAGCTGCAGGAGAGCCTGCTGCGGGATGAGGGGACGTCCCAG; GAGGAGATGGAGAGCCGCTTTGAGCTGGAGAAGTCAGAGAGCCTGCTGGTGACCCCCTCA; GCTGACATCCTGGAGCCCTCTCCACACCCAGACATGCTGTGCTTTGTGGAAGACCCTACT; TTCGGATATGAGGACTTCACTCGGAGAGGGGCTCAGGCACCCCCTACCTTCCGGGCCCAG; GATTATACCTGGGAAGACCATGGCTACTCGCTGATCCAGCGGCTTTACCCTGAGGGTGGG; CAGCTGCTGGATGAGAAGTTCCAGGCAGCCTATAGCCTCACCTACAATACCATCGCCATG; CACAGTGGTGTGGACACCTCCGTGCTCCGCAGGGCCATCTGGAACTATATCCACTGCGTC; TTTGGCATCAGATATGATGACTATGATTATGGGGAGGTGAACCAGCTCCTGGAGCGGAAC; CTCAAGGTCTATATCAAGACAGTGGCCTGCTACCCAGAGAAGACCACCCGAAGAATGTAC; AACCTCTTCTGGAGGCACTTCCGCCACTCAGAGAAGGTCCACGTGAACTTGCTGCTCCTG; GAGGCGCGCATGCAAGCCGCTCTGCTGTACGCCCTCCGTGCCATCACCCGCTACATGACC; TGA; ; Clone variation with respect to NM_031459.4; 39 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_031459 unedited; CACCAGCGGGGGAGCTGAGGAGCGCTGGGTCCGGGAGCAGCCCTGGCCCCTGCGGACTTC; CGAGGCCGTNGAAAACCCCTGCGCTGCGGCCCTTCCCAGGCCCCCGAGGCCGTTCGCCGT; TCCCGAAGCCCGACTGGGGGAAGAGTCCAGCACCAAAGCGGCCGTTCTCGGATTCCGGAG; CGTTCTGGAGCCCCGAGAGACGCCCCGGGGTTCTAGAAGCTCCCCGGCGGCGCCCAGTCC; CGGCTTCATTCGGGCGTCCCTCCGAAACCCACTCGGGTGCACGGGTCGTCGGCGAGCCGC; GACCGGGTCCTGGCGCGCACCATGATCGTGGCGGACTCCGAGTGCCGCGCAGAGCTCAAA; GACTACCTGCGGTTCGCCCCGGGCGGCGTCGGCGACTCGGGCCCCGGAGAGGAGCAGAGG; GAGAGCCGGGCTCGGCGAGGCCCTCGAGGGCCCAGCGCCTTCATCCCCGTGGAGGAGGTC; CTTCGGGAGGGGGCTGAGAGCCTCGAGCAGCACCTGGGGCTGGAGGCACTGATGTCCTCT; GGGCGAGTAGACAACCTGGCAGTGGTGATGGGCCTGCACCCTGACTACTTTACCAGCTTC; TGGCGCCTGCACTACCTGCTGCTGCACACGGATGGTCCCTTGGCCAGCTNCTGGCGCCAC; TACATTGCCATCATGGGCTGCCGCCG;
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_031459 unedited; NCNANGATCGAGTTTTTTTTTTTTTTTTTTCTAAAAAAATCTGCTTTTTTTTTTTTTATG; TACTTGGCCTCTCTCCTGACGCCTCACACCATTAAGCATGGAGAAAAGGGAAAAAGGGCA; AAGGAAGTCAAAAAACTGAACTAGGATTCGGGCAACAGCCTCAGGCTGCCCAACAGAACA; GGCTTTTAGGGAACTGGACACACAGACCAGCTGTGACCCTGACTTTCACATTGATGGGTG; AATGGCAAGTAGGAGGTAATGAAATCTGGAAATGACAGGGGAGAGAAGGCAAAGCTGCCT; GGAGTGTCAGTCCCGGGAGCATTTGCCCCTCTCCCCCGGGGCCAGCCAGGGACTTCCCAG; TTCAAGAAGGCCCAACACTTGTGGCACAATAATTCCGAGCTTGCCCGGCTTCTTTTCTGG; GCCCTCTGCTCTGTGGGCCGGGAAAGAGGAAGGGTGGGGCCCCTAGGATTTCCAGTGCCC; TTCAGCTTCCAAGAACGGGGCTAGATCCCCAAATCCGGGCATGGACTGGCCATTCCATGA; GAAAAGGAGGGGGTGGCCTTGGACTGGCATTAAAACAAACCACTGGACGTGGGAAGGGTG; GGCATGGGCAACAAAGGTCCTGGGGCTGTCCCCAACAAAAAAATCCCTTTGGGGAGTGAA; ACGGGCCCAGGTCTCGTCCAGAGTAAGGGCTTTTCCGGGGGATGGCCCGGAGGGGGTACA; CAAAAAAGCTTTTTGGCCCCCCCCCGGAAAACAGGTTCCCTGGGCCCTTTTCGAGTGGGG; GAAGGCTCCCCCCAAAAGATGTGAATCTTCGGGGGGGGCTCTC;
• Restriction Sites: NotI-NotI
• ACCN: NM_031459
• Insert Size: 2800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_031459.3, NP_113647.1
• RefSeq Size: 3503 bp
• RefSeq ORF: 1443 bp
• Locus ID: 83667
• UniProt ID: P58004
• Cytogenetics: 1p35.3
• Domains: PA26
• Protein Pathways: p53 signaling pathway
• Summary: This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions. [provided by RefSeq, Jul 2008]