CD98 (SLC3A2) (NM_002394) Human Untagged Clone

SKU SC127353

SLC3A2 (untagged)-Human solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 (SLC3A2), transcript variant 3

Product Data

• Type: Human Untagged Clone
• Target Symbol: CD98
• Synonyms: 4F2; 4F2HC; 4T2HC; CD98; CD98HC; MDU1; NACAE
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127353 sequence for NM_002394 edited (data generated by NextGen Sequencing); ATGGAGCTACAGCCTCCTGAAGCCTCGATCGCCGTCGTGTCGATTCCGCGCCAGTTGCCT; GGCTCACATTCGGAGGCTGGTGTCCAGGGTCTCAGCGCGGGGGACGACTCAGAGTTGGGG; TCTCACTGTGTTGCCCAGACTGGTCTCGAACTCTTGGCCTCAGGTGATCCTCTTCCCTCA; GCTTCCCAGAATGCCGAGATGATAGAGACGGGGTCTGACTGTGTTACCCAGGCTGGTCTT; CAACTCTTGGCCTCAAGTGATCCTCCTGCCTTAGCTTCCAAGAATGCTGAGGTTACAGGC; ACCATGAGCCAGGACACCGAGGTGGATATGAAGGAGGTGGAGCTGAATGAGTTAGAGCCC; GAGAAGCAGCCGATGAACGCGGCGTCTGGGGCGGCCATGTCCCTGGCGGGAGCCGAGAAG; AATGGTCTGGTGAAGATCAAGGTGGCGGAAGACGAGGCGGAGGCGGCAGCCGCGGCTAAG; TTCACGGGCCTGTCCAAGGAGGAGCTGCTGAAGGTGGCAGGCAGCCCCGGCTGGGTACGC; ACCCGCTGGGCACTGCTGCTGCTCTTCTGGCTCGGCTGGCTCGGCATGCTTGCTGGTGCC; GTGGTCATAATCGTGCGAGCGCCGCGTTGTCGCGAGCTACCGGCGCAGAAGTGGTGGCAC; ACGGGCGCCCTCTACCGCATCGGCGACCTTCAGGCCTTCCAGGGCCACGGCGCGGGCAAC; CTGGCGGGTCTGAAGGGGCGTCTCGATTACCTGAGCTCTCTGAAGGTGAAGGGCCTTGTG; CTGGGTCCAATTCACAAGAACCAGAAGGATGATGTCGCTCAGACTGACTTGCTGCAGATC; GACCCCAATTTTGGCTCCAAGGAAGATTTTGACAGTCTCTTGCAATCGGCTAAAAAAAAG; AGCATCCGTGTCATTCTGGACCTTACTCCCAACTACCGGGGTGAGAACTCGTGGTTCTCC; ACTCAGGTTGACACTGTGGCCACCAAGGTGAAGGATGCTCTGGAGTTTTGGCTGCAAGCT; GGCGTGGATGGGTTCCAGGTTCGGGACATAGAGAATCTGAAGGATGCATCCTCATTCTTG; GCTGAGTGGCAAAATATCACCAAGGGCTTCAGTGAAGACAGGCTCTTGATTGCGGGGACT; AACTCCTCCGACCTTCAGCAGATCCTGAGCCTACTCGAATCCAACAAAGACTTGCTGTTG; ACTAGCTCATACCTGTCTGATTCTGGTTCTACTGGGGAGCATACAAAATCCCTAGTCACA; CAGTATTTGAATGCCACTGGCAATCGCTGGTGCAGCTGGAGTTTGTCTCAGGCAAGGCTC; CTGACTTCCTTCTTGCCGGCTCAACTTCTCCGACTCTACCAGCTGATGCTCTTCACCCTG; CCAGGGACCCCTGTTTTCAGCTACGGGGATGAGATTGGCCTGGATGCAGCTGCCCTTCCT; GGACAGCCTATGGAGGCTCCAGTCATGCTGTGGGATGAGTCCAGCTTCCCTGACATCCCA; GGGGCTGTAAGTGCCAACATGACTGTGAAGGGCCAGAGTGAAGACCCTGGCTCCCTCCTT; TCCTTGTTCCGGCGGCTGAGTGACCAGCGGAGTAAGGAGCGCTCCCTACTGCATGGGGAC; TTCCACGCGTTCTCCGCTGGGCCTGGACTCTTCTCCTATATCCGCCACTGGGACCAGAAT; GAGCGTTTTCTGGTAGTGCTTAACTTTGGGGATGTGGGCCTCTCGGCTGGACTGCAGGCC; TCCGACCTGCCTGCCAGCGCCAGCCTGCCAGCCAAGGCTGACCTCCTGCTCAGCACCCAG; CCAGGCCGTGAGGAGGGCTCCCCTCTTGAGCTGGAACGCCTGAAACTGGAGCCTCACGAA; GGGCTGCTGCTCCGCTTCCCCTACGCGGCCTGA; ; Clone variation with respect to NM_002394.5;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002394 unedited; AATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGAGATCACTGCCTCACGGC; GATCCTGGACTGACGGTCACGACTGCCTACCCTCTAACCCTGTTCTGAGCTGCCCCTTGC; CCACACACCCCAAACCTGTGTGCAGGATCCGCCTCCATGGAGCTACAGCCTCCTGAAGCC; TCGATCGCCGTCGTGTCGATTCCGCGCCAGTTGCCTGGCTCACATTCGGAGGCTGGTGTC; CAGGGTCTCAGCGCGGGGGACGACTCAGAGTTGGGGTCTCACTGTGTTGCCCAGACTGGT; CTCGAACTCTTGGCCTCAGGTGATCCTCTTCCCTCAGCTTCCCAGAATGCCGAGATGATA; GAGACGGGGTCTGACTGTGTTACCCAGGCTGGTCTTCAACTCTTGGCCTCAAGTGATCCT; CCTGCCTTAGCTTCCAAGAATGCTGAGGTTACAGGCACCATGAGCCAGGACACCGAGGTG; GATATGAAGGAGGTGGAGCTGAATGAGTTAGAGCCCGAGAAGCAGCCGATGAACGCGGCG; TCTGGGGCGGCCATGTCCCTGGCGGGAGCCGAGAAGAATGGTCTGGTGAAGATCAAGGTG; GCGGAAGACGAGGCGGAGGCGGCAGCCGCGGCTAAGTTCACGGGCCTGTCCAGGAGGAGC; TGCTGAAGGTGGCANGCAGCCCCGGCTGGGTACGCACCCGCTGGGCACTGCTGCTGCTCT; TCTGGCTCGGCTGGCTCGGCATGCTTGCTGGTGCCCGTGTCATAATCGTGCGAGCGCCCG; CGTGTCGCGAGCTACCGCGCANAAGTGGTGCACACGGGCGCCCTCTACGCATNGGCGACC; TCAGGCCTTCAGGCCACGCGCGGGCANCCTGCGGTCTGAAAGGGCGTCTCGATACCTGAC; TTCTGAAGTGAAAGCCCTGGGCTGGGTCCATCCAGAACAGNGGGATGAGCGCTCN;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002394 unedited; AGTAAAGCACTGGGGNAGGGTCACAGGGNTGCCACCCGGGCTCTGTTCAGGAAACAGCTA; TGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAGGGAAGACTTCAC; CATGCAGGGGTGACTTTTATTTGAAGGCAGAAAACACCCTATTTGGGGGTTCACTCATAA; TCTGCAACAGTTTGTTTGTTTGTTTTTAAAAAAGAGAAAAATCAGAAGCCAAAGGGCCTG; GGAAGGAAAGGAGAAGGGTAGTGGGTCCATGTCAGGCTGAAGTCAGGCCGCGTAGGGGAA; GCGGAACAGCAGCCCTTCGTGAGGCTCCAGTTTCAGGCGTTCCAGCTCAAGAGGGGAGCC; CTCCTCACGGCCTGGCTGGGTGCTGAGCAAGAGGTCAGCCTTGGCTGGCAGGCTGGCGCT; GGCAGGCAGGTCGGATGCCTGCAATCCATCCGATAGGCCCACATCCCCAAAGTTAAGCAC; TACCAAAAAACGCTCATTCTGGTCCCAGTGGCGGATATAGGAGAAGAGTCCAGGCCCAGC; GGAGAACGCGTGGAATTCCCCATGCATTAGGGAGCGCTCCTTACTCCGCTGGGCACTCAG; CCCCCCGAACAAAGAAAGGAGGGAGCCAGGGTCTTTTCTCCTGGACCCTCACAGTATGTT; GGGACTTACAACCCCTGGGATGTCAGGGAACCTGGTCCTCTCCCCCACTTTTTTGGAGCC; TCCTAAGCCGGTCCCGGAAAGGGAATTCGCTTCAAGCCATTCTTCTACCCCTGAGCTTAA; AAAAAGGGGGCCCCGGGCGAGGTAAACAAAATCATCGGCGGTAGTTCG;
• Restriction Sites: NotI-NotI
• ACCN: NM_002394
• Insert Size: 2500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002394.4, NP_002385.3
• RefSeq Size: 2315 bp
• RefSeq ORF: 1893 bp
• Locus ID: 6520
• UniProt ID: P08195
• Cytogenetics: 11q12.3
• Domains: Aamy, alpha-amylase
• Protein Families: Transmembrane
• Summary: This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized. [provided by RefSeq, Nov 2010]; Transcript Variant: This variant (3) contains an alternate in-frame exon and lacks an alternate exon in the 5' coding region, compared to variant 2, resulting in a shorter protein (isoform c).