Quiescin Q6 (QSOX1) (NM_002826) Human Untagged Clone

SKU SC127220

QSOX1 (untagged)-Human quiescin Q6 sulfhydryl oxidase 1 (QSOX1), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: Quiescin Q6
• Synonyms: Q6; QSCN6
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127220 sequence for NM_002826 edited (data generated by NextGen Sequencing); ATGAGGAGGTGCAACAGCGGCTCCGGGCCGCCGCCGTCGCTGCTGCTGCTGCTGCTGTGG; CTGCTCGCGGTTCCCGGCGCTAACGCGGCCCCGCGGTCGGCGCTCTATTCGCCTTCCGAC; CCGCTGACGCTGCTGCAGGCGGACACGGTGCGCGGCGCGGTGCTGGGCTCCCGCAGCGCC; TGGGCCGTGGAGTTCTTCGCCTCCTGGTGCGGCCACTGCATCGCCTTCGCCCCGACGTGG; AAGGCCCTGGCCGAAGACGTCAAAGCCTGGAGGCCGGCCCTGTATCTCGCCGCCCTGGAC; TGTGCTGAGGAGACCAACAGTGCAGTCTGCAGAGACTTCAACATCCCTGGCTTCCCGACT; GTGAGGTTCTTCAAGGCCTTTACCAAGAACGGCTCGGGAGCAGTATTTCCAGTGGCTGGT; GCTGACGTGCAGACGCTGCGGGAGAGGCTCATTGACGCCCTGGAGTCCCATCATGACACG; TGGCCCCCAGCCTGTCCCCCACTGGAGCCTGCCAAGCTGGAGGAGATTGATGGATTCTTT; GCGAGAAATAACGAAGAGTACCTGGCTCTGATCTTTGAAAAGGGAGGCTCCTACCTGGGT; AGAGAGGTGGCTCTGGACCTGTCCCAGCACAAAGGCGTGGCGGTGCGCAGGGTGCTGAAC; ACAGAGGCCAATGTGGTGAGAAAGTTTGGTGTCACCGACTTCCCCTCTTGCTACCTGCTG; TTCCGGAATGGCTCTGTCTCCCGAGTCCCCGTGCTCATGGAATCCAGGTCCTTCTATACC; GCTTACCTGCAGAGACTCTCTGGGCTCACCAGGGAGGCTGCCCAGACCACAGTTGCACCA; ACCACTGCTAACAAGATAGCTCCCACTGTTTGGAAATTGGCAGATCGCTCCAAGATCTAC; ATGGCTGACCTGGAATCTGCACTGCACTACATCCTGCGGATAGAAGTGGGCAGGTTCCCG; GTCCTGGAAGGGCAGCGCCTGGTGGCCCTGAAAAAGTTTGTGGCAGTGCTGGCCAAGTAT; TTCCCTGGCCGGCCCTTAGTCCAGAACTTCCTGCACTCCGTGAATGAATGGCTCAAGAGG; CAGAAGAGAAATAAAATTCCCTACAGTTTCTTTAAAACTGCCCTGGACGACAGGAAAGAG; GGTGCCGTTCTTGCCAAGAAGGTGAACTGGATTGGCTGCCAGGGGAGTGAGCCGCATTTC; CGGGGCTTTCCCTGCTCCCTGTGGGTCCTCTTCCACTTCTTGACTGTGCAGGCAGCTCGG; CAAAATGTAGACCACTCACAGGAAGCAGCCAAGGCCAAGGAGGTCCTCCCAGCCATCCGA; GGCTACGTGCACTACTTCTTCGGCTGCCGAGACTGCGCTAGCCACTTCGAGCAGATGGCT; GCTGCCTCCATGCACCGGGTGGGGAGTCCCAACGCCGCTGTCCTCTGGCTCTGGTCTAGC; CACAACAGGGTCAATGCTCGCCTTGCAGGTGCCCCCAGCGAGGACCCCCAGTTCCCCAAG; GTGCAGTGGCCACCCCGTGAACTTTGTTCTGCCTGCCACAATGAACGCCTGGATGTGCCC; GTGTGGGACGTGGAAGCCACCCTCAACTTCCTCAAGGCCCACTTCTCCCCAAGCAACATC; ATCCTGGACTTCCCTGCAGCTGGGTCAGCTGCCCGGAGGGATGTGCAGAATGTGGCAGCC; GCCCCAGAGCTGGCGATGGGAGCCCTGGAGCTGGAAAGCCGGAATTCAACTCTGGACCCT; GGGAAGCCTGAGATGATGAAGTCCCCCACAAACACCACCCCACATGTGCCGGCTGAGGGA; CCTGAGGCAAGTCGACCCCCGAAGCTGCACCCTGGCCTCAGAGCTGCACCAGGCCAGGAG; CCTCCTGAGCACATGGCAGAGCTTCAGAGGAATGAGCAGGAGCAGCCGCTTGGGCAGTGG; CACTTGAGCAAGCGAGACACAGGGGCTGCATTGCTGGCTGAGTCCAGGGCTGAGAAGAAC; CGCCTCTGGGGCCCTTTGGAGGTCAGGCGCGTGGGCCGCAGCTCCAAGCAGCTGGTCGAC; ATCCCTGAGGGCCAGCTGGAGGCCCGAGCTGGACGGGGCCGAGGCCAGTGGCTGCAGGTG; CTGGGAGGGGGCTTCTCTTACCTGGACATCAGCCTCTGTGTGGGGCTCTATTCCCTGTCC; TTCATGGGCCTGCTGGCCATGTACACCTACTTCCAGGCCAAGATAAGGGCCCTGAAGGGC; CATGCTGGCCACCCTGCAGCCTGA; ; Clone variation with respect to NM_002826.4; 246 g=>c;435 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002826 unedited; AAAAACAACGATTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTGGTGGTGAGCGCA; GCGCCGAGGATGAGGAGGTGCAACAGCGGCTCCGGGCCGCCGCCGTCGCTGCTGCTGCTG; CTGCTGTGGCTGCTCGCGGTTCCCGGCGCTAACGCGGCCCCGCGGTCGGCGCTCTATTCG; CCTTCCGACCCGCTGACGCTGCTGCAGGCGGACACGGTGCGCGGCGCGGTGCTGGGCTCC; CGCAGCGCCTGGGCCGTGGAGTTCTTCGCCTCCTGGTGCGGCCACTGCATCGCCTTCGCC; CCGACGTGGAAGGCCCTGGCCGAAGACGTCAAAGCCTGGAGGCCGGCCCTGTATCTCGCC; GCCCTGGACTGTGCTGAGGAGACCAACAGTGCAGTCTGCAGAGACTTCAACATCCCTGGC; TTCCCGACTGTGAGGTTCTTCAAGGCCTTTACCAAGAACGGCTCGGGAGCAGTATTTCCA; GTGGCTGGTGCTGACGTGCAGACGCTGCGGGAGAGGCTCATTGACGCCCTGGAGTCCCAT; CATGACACGTGGCCCCCAGCCTGTCCCCCACTGGAGCCTGCCAAGCTGGAGGAGATTGAT; GGATTCTTTGCGAGAAATAACGAAGAGTACCTGGCTCTGATCTTTGAAAAGGGAGGCTCC; TACCTGNGTAGAGAGGTGGCTCTGGACCTGTCCCAGCACAAAGGCGTGGCGGTGCGCAGG; NTGCTGAACACAGAGGCCAATGTGGTGAGAAAAGTTGGTGTCACCGACTTCCCCTCTTGC; TACCTGCTGTNTCCGAATGGCTCTGTCTCCCGAGTCCCGTGCTCATGGAATCNNCAGTCC; TTCTATACCGCTACCTGCAGAGACTCTCTGGGCTACCAGGGAGGCTGCCCAGACACAGTT; GCACCACACTGCTNACAGATACTCCACTGTTTGGAAATGGCAGATC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002826 unedited; GTCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTCTTTTTTTTTTGCCTTAACAAAAAAAT; TTATTCCACACACCTCCCAGGCAGGGGGTAGCGTGGGAATCAAGCATGTGTAAGGCACTG; CCCCCGCCAGACCCTTCTAACTTCTGCACACTGGAAGGTGAAACCTGGAGAGAGAAGACA; CTCCCCTCCCTAGCTTCTACCTGGCACCCTCCAAAGATGAGCATTCATCTTGGAGACCAA; AATAAAAAAGGACAAAAGACCAGGCTCAGAGGGAGCAGAGCTCAATGGGGGGAAGTGAAA; GCAGCCATCTTCTCCTGCAGCTAAGCCAGGGCAAGGCACTAGAGACCCACATCCTTCCCA; TGCCACCAACTCGTCAGGTCCCACCAAGCAAGCCACTCACCCTACAGCCCAGCAACCATG; GCTTGCCTCACCTGGGAGACCAGCACGACTTCCAGAAGCTTCCAAACCCCACCCTGAAGC; CAAACCCCACCCAGGAGGTCTGAGGAGCTGGAGGCTGGCCAGGCATAGAGGGCCCGGGGT; GGCCCTTCCTCCCAGGGTGCAAAGGCTTCTTCATTGTCCGGAAGGGAGCAGGGTGGGCGG; AGCCCCAGCAGCTAGTGAGGAGTTCCATTCCAGCCCACCCAGCTGGGGGACCCTCCTCTG; GCTTCACTTGCCCCAGNTGAGGGCCAAGACCAAGCAGGAGAGACTGAGGCTTCAGTGAGA; ATGAGGCAGGACTTCAAATAAGCTGAAAAACAGGAATGTGGTGCTTAGAAGCCCAGGGAA; CTGACCTGGCCTATTGCCACTGCCCGGGGCTGCCCTCCCTGCACAGNAGGGGAACCTGGG; ACCTGCTCCTGGTCTTTGGGCAAAGGGAGCTTCTGTCCTACCACCCCAAAGGCTTACTGG; AGCACTGGTTTCCTGATTCCCCACCTTTAGCCACACAGACCAAGGTGGGAGTAGGAATGG; TGCCCAGGCCCTTTCACACCACAACACCACATTC;
• Restriction Sites: NotI-NotI
• ACCN: NM_002826
• Insert Size: 3600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002826.4, NP_002817.2
• RefSeq Size: 3316 bp
• RefSeq ORF: 2244 bp
• Locus ID: 5768
• UniProt ID: O00391
• Cytogenetics: 1q25.2
• Domains: Evr1_Alr, thiored
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Summary: This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Sequence Note: The 3' UTR of this gene may extend about 2 kbp further to another polyA site.