TM4SF2 (TSPAN7) (NM_004615) Human Untagged Clone

CAT#: SC126663

TSPAN7 (untagged)-Human tetraspanin 7 (TSPAN7)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TM4SF2
• Synonyms: A15; CCG-B7; CD231; DXS1692E; MRX58; MXS1; TALLA-1; TM4SF2; TM4SF2b
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126663 sequence for NM_004615 edited (data generated by NextGen Sequencing)
  ATGGCATCGAGGAGAATGGAGACCAAACCTGTGATAACCTGTCTCAAAACCCTCCTCATC
  ATCTACTCCTTCGTCTTCTGGATCACTGGGGTGATCCTGCTGGCTGTTGGAGTCTGGGGC
  AAACTTACTCTGGGCACCTATATCTCCCTTATTGCCGAGAACTCCACAAATGCTCCCTAT
  GTGCTCATCGGAACTGGCACCACTATTGTTGTCTTTGGCCTGTTTGGATGCTTTGCTACA
  TGTCGTGGTAGCCCATGGATGCTGAAACTGTATGCCATGTTTCTGTCCCTGGTGTTCCTG
  GCTGAGCTCGTAGCTGGCATTTCAGGGTTTGTGTTTCGTCATGAGATCAAGGACACCTTC
  CTGAGGACTTACACGGACGCTATGCAGACTTACAATGGCAATGATGAGAGGAGCCGGGCA
  GTGGACCATGTGCAGCGCAGCCTGAGCTGCTGTGGTGTGCAGAACTACACCAACTGGAGC
  ACCAGCCCCTACTTCCTGGAGCATGGCATCCCCCCCAGCTGCTGCATGAACGAAACTGAT
  TGTAATCCCCAGGATCTACACAATCTGACTGTGGCCGCCACCAAAGTTAACCAGAAGGGT
  TGTTATGATCTGGTAACTAGTTTCATGGAGACTAACATGGGAATCATCGCTGGAGTGGCG
  TTTGGAATCGCATTCTCCCAGTTAATTGGCATGCTGCTGGCCTGCTGTCTGTCCCGGTTC
  ATCACGGCCAATCAGTATGAGATGGTGTAA
  
  Clone variation with respect to NM_004615.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004615 unedited
  TCCCCACCTCCTGTAGGTGGCCGCGCAATCGGCACGAGGCCCGCCCGCTGCCTGCCGCCG
  CCGCCGCCGCCGCCGGAGCTCTGTAGTATGGCATCGAGGAGAATGGAGACCAAACCTGTG
  ATAACCTGTCTCAAAACCCTCCTCATCATCTACTCCTTCGTCTTCTGGATCACTGGGGTG
  ATCCTGCTGGCTGTTGGAGTCTGGGGCAAACTTACTCTGGGCACCTATATCTCCCTTATT
  GCCGAGAACTCCACAAATGCTCCCTATGTGCTCATCGGAACTGGCACCACTATTGTTGTC
  TTTGGCCTGTTTGGATGCTTTGCTACATGTCGTGGTAGCCCATGGATGCTGAAACTGTAT
  GCCATGTTTCTGTCCCTGGTGTTCCTGGCTGAGCTCGTAGCTGGCATTTCAGGGTTTGTG
  TTTCGTCATGAGATCAAGGACACCTTCCTGAGGACTTACACGGACGCTATGCAGACTTAC
  AATGGCAATGATGAGAGGAGCCGGGCAGTGGACCATGTGCAGCGCAGCCTGAGCTGCTGT
  GGTGTGCAGAACTACACCAACTGGAGCACCAGCCCCTACTTCCTGGAGCATGGCATCCCC
  CCCAGCTGCTGCATGAACGAAACTGATTGTAATCCCCAGGATCTACACAATCTGACTGTG
  GCCGCCACCAAAGTTAACCAGAAGGGTTGTTATGATCTGGTAACTAGTTTCATGGAGACT
  AACATGGGAATCATCGCTTGAGTGGCGTTTGGAATCGATTCTCCCAGTTAATTGCATGCT
  GCTGGCCTGCTGTCTGTCCCCGTTCATCCACGCCAATCATTATGAGATGTGTAAGGGAGA
  TTCTTTCAATATGACGNATTAAAAACTGTTTAAAAGGACTGCCCCATCCTTGAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004615 unedited
  TGAGGCCCGCATTTCTACAGTCGAGTTTTCCCCTCCCCCCCTTTGCAACTGCTTTATTTA
  TTAATACATATATCACAAATGTTCACAATATCAATGCCTTGTTGTTGGCATGCTATTAAC
  AGGCATTATTTTTGAAGATCTTTTAAAAATATTTTGACTTGTTCCCCCTTCACACTCATT
  TTCACATTGTTTGGACGAGGTCCTCACTGTCTACTCTGCCCATGTTCCAAAAACCACAGA
  CAGAAGTCCTAAAATAACACAATAGCACTTAATTGTGGACAAACAACCTATCATGGTCTT
  TACAATAAGCAACAACACAGCTTTGGAACAGGGCCATACAGGTTTTAACTGATAGGCAAA
  GATGCCCTAAACTGCCTACCCATACCCAGGTATGTAACAAGCAAGGATGCCCCCCCCATT
  CCCTTTTTCTCATGTATGAACATGCTCTCTTCTCTCCAGCGACCCCCTTTGAACCCCCCT
  TTTTATCCCCCATCCCCTCTCCAAAAGCAGTAAGCCTTACCCAGGGGACACCATACCAAT
  GACACCACTCTTTAGACCCCCCAATCACCCCCGCTCACCAATTAAATGTCTGCGCCTTTT
  ATACAGCCAGCATCTTACACGACCCTTCTCCCTACTTTCCGGTCCACCCGTTCCAATCCA
  GTTTTATTATCTTATTCCCCCACGACTGCCTCCCGTCTACTCCTACGCAGGGCCCCTCCC
  CCGGGCTTTGCCCTGTGTTTTTTTTTTCCCCCCTGTTTCCCCCCCCCCCCCCCCCCCGCC
  TTTCCAAAGGTCATTATCAGAACCGGCTCAAGTGGATAAACACGCCCCCCACACCCCACT
  CTTTGTCTACGCTTAGCACCCCAATTTTTCTCCCCCCCCGCTTTTATTTTTGCACCCCTT
  ACCTCGGCGCACCTTTTTAAAAATATGCTATCCCCTTTCCAACACTCTTTACCTCCTCAC
  TCCTCGCCTCCACCCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004615
• Insert Size: 1890 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004615.2, NP_004606.2
• RefSeq Size: 1813 bp
• RefSeq ORF: 750 bp
• Locus ID: 7102
• UniProt ID: P41732
• Cytogenetics: Xp11.4
• Domains: transmembrane4
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked cognitive disability and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. [provided by RefSeq, Jul 2008]