DMRT1 (NM_021951) Human Untagged Clone

SKU SC125918

DMRT1 (untagged)-Human doublesex and mab-3 related transcription factor 1 (DMRT1)

Product Data

• Type: Human Untagged Clone
• Target Symbol: DMRT1
• Synonyms: CT154; DMT1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_021951 edited; GGGGGCCAGAGTGCTCGCACTTCTCCTAGGGGCACCATGCCCAACGACGAGGCATTCAGC; AAGCCCTCTACACCGTCGGAAGCCCCTCACGCCCCCGGGGTACCGCCGCAGGGCAGAGCC; GGGGGCTTTGGCAAAGCGTCTGGGGCGCTAGTGGGGGCGGCCAGCGGCTCGAGCGCCGGG; GGCAGCAGCAGAGGAGGCGGCTCCGGCTCCGGGGCGTCGGACCTGGGTGCCGGGAGCAAG; AAGTCCCCGCGGCTGCCCAAGTGCGCACGCTGCAGGAACCACGGCTACGCCTCGCCGCTC; AAGGGCCACAAGCGCTTCTGCATGTGGCGCGACTGCCAGTGCAAGAAGTGCAACCTGATC; GCCGAGAGGCAGCGCGTGATGGCCGCGCAGGTGGCCCTGAGAAGGCAGCAGGCCCAGGAG; GAGGAATTGGGTATCAGCCACCCCATCCCACTGCCCAGTGCGGCCGAGCTGCTTGTCAAA; AGAGAGAACAATGGCAGTAACCCGTGCCTCATGACTGAGTGCAGTGGCACCTCTCAGCCA; CCGCCGGCCAGTGTCCCCACCACTGCAGCTTCAGAGGGACGTATGGTCATCCAGGATATT; CCTGCTGTCACCAGCAGAGGGCATGTGGAGAACACACCTGACCTGGTTTCAGACTCCACC; TACTACAGCAGCTTCTACCAGCCGTCTCTGTTTCCTTATTACAACAATCTATACAACTGC; CCGCAGTACTCCATGGCCTTGGCTGCTGATTCTGCTTCTGGGGAGGTGGGAAATCCCCTC; GGGGGATCCCCTGTGAAGAACAGCCTTCGGGGCCTCCCCGGACCTTATGTGCCTGGTCAG; ACAGGAAACCAGTGGCAGATGAAGAACATGGAGAACCGCCATGCAATGAGCTCCCAGTAC; AGGATGCATTCTTACTACCCGCCTCCCTCTTACCTGGGCCAGAGCGTGCCCCAGTTCTTC; ACTTTTGAGGATGCTCCCTCTTACCCGGAAGCCAGGGCGAGCGTATTCTCGCCGCCCAGC; AGTCAAGATTCTGGCTTGGTTTCCCTCTCGAGCAGCTCTCCTATTAGTAACAAGAGCACA; AAGGCAGTGCTTGAATGTGAGCCTGCGTCGGAGCCCAGCAGCTTCACAGTCACTCCCGTC; ATCGAGGAGGACGAGTGAGCAGTGCCTGCTGCCGATGGCGGTTCACTTGGAGTAACAGGC; TTATTCCACTTTCCATGGGGTTTGTTAATATTTTGCATTGACTCATACTATCTTAACTGT; TGAGAACGTATTTGGTTTATATTCCTTAGAGTTTAGTCCAGAGGCTGTAACACATTTGTA; ATACTTTAGGGTCCGTGACTACCATCTGCATGATTTAAGTGCTTTACTCACGGAGTTTAA; ATAATAGTGTTCATTTTTTTAATGACACTGGTTTCATGTAGTTTTCAAGAAATAAAAGAA; TTCATTCAAGTGAAGCCATTTGTGTGCCTCTAAATGAGTCATCTAATTAGATGTTACTTT; TAGTTTTAAAATGAAATCTTAGGTGCCTTAGGGGTTTTTTTTTTTTTAAGTATTTTTTAA; AAACCTGCAAAGATATAAATTTAGCCAAGTTACCTGACGGGTGAGAAGAAAAGAGCAGGC; AAAATTAGTGATTTTTTTAGAAGTCTGCTAAATGGATATATTGTGTGTGTTGCTGTTGGA; AATAGCCCCACCCCATCCTCCCAATCCAAAACGTAACTGAAATATAATCAGAAACATTAA; AGCCTGTAAAAAAAAATTGCTGCGTTTTTGGTAAAGGGTGTAATTTGTAAACAGTGCAAT; TTAAAGTGACCTTAGTGATGCAGAGTTCCTGAGTGGTGTTTGTAGAATGAGTTTATCATA; CATTCTTTCTACTACTGGAAAAAAATGGATGCAGTCTGGACTGTTGTAACCTTAGGTTGT; AATCTGATTTGGAAATAAGTACATCTTTAAAAGTTGCTACAGATTTGAGTTCATGATTTT; GTTAAAAATTGCTATGGAGTACTTTGTTATATAACAGAAGCCATCCTGAAATGAAACTAG; TCTAAAAAAATTCATTGTTCTACTTAGTTGCAGCTGTACCTGAAATAAAAATGTTATTGA; TGACTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021951 unedited; NGGCGTTCANAATTTTGTNAATACGAATNCACTATAGGGNNCGGCCGCGNAATTCAGTTN; CTNNGGTACCGGTCCGGNAATTCCCGGGATGGGGGNCCAGATGCTCGCACTTCTCCTAGG; GGCACCATGCCCAACGACGAGGCATTCAGCAAGCCCTCTACACCGTCGGAAGCCCCTCAC; GCCCCCGGGGTACCGCCGCAGGGCAGAGCCGGGGGCTTTGGCAAAGCGTCTGGGGCGCTA; GTGGGGGCGGCCAGCGGCTCGAGCGCCGGGGGCAGCAGCAGAGGAGGCGGCTCCGGCTCC; GGGGCGTCGGACCTGGGTGCCGGGAGCAAGAAGTCCCCGCGGCTGCCCAAGTGCGCACGC; TGCAGGAACCACGGCTACGCCTCGCCGCTCAAGGGCCACAAGCGCTTCTGCATGTGGCGC; GACTGCCAGTGCAAGAAGTGCAACCTGATCGCCGAGAGGCAGCGCGTGATGGCCGCGCAG; GTGGCCCTGAGAAGGCAGCAGGCCCAGGAGGAGGAATTGGGTATCAGCCACCCCATCCCA; CTGCCCAGTGCGGCCGAGCTGCTTGTCAAAAGAGAGAACAATGGCAGTAACCCGTGCCTC; ATGACTGAGTGCAGTGGCACCTCTCAGCCACCGCCGGCCAGTGTCCCCACCACTGCAGCT; TCAGAGGGACGTATGGTCATCCAGGATATTCCTGCTGTCACCAGCAGAGGGCATGTGGAG; AACACACCTGACCTGGTTTCAGACTCCACCTACTACAGCAGCTTCTACCAGCCGTCTCTG; TTTCCTTATTACAACAATCTATACAACTGCCCGCAGTACTCCATGGCCTTGGCTGCTGAT; TCTGCTTCTGGNGAGGGTGGGGAATCCCCTCGGGGGGATCCCCTGTGAAGAACAGCCTTC; GGGGACTACCCCGGACCTATGTGA;
• Restriction Sites: NotI-NotI
• ACCN: NM_021951
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_021951.2, NP_068770.2
• RefSeq Size: 2229 bp
• RefSeq ORF: 1122 bp
• Locus ID: 1761
• UniProt ID: Q9Y5R6
• Cytogenetics: 9p24.3
• Protein Families: Druggable Genome, Transcription Factors
• Summary: This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq, Jul 2008]