MMP3 (NM_002422) Human Untagged Clone

SKU SC123913

MMP3 (untagged)-Human matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3)

Product Data

• Type: Human Untagged Clone
• Target Symbol: MMP3
• Synonyms: CHDS6; MMP-3; SL-1; STMY; STMY1; STR1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC123913 sequence for NM_002422 edited (data generated by NextGen Sequencing); ATGAAGAGTCTTCCAATCCTACTGTTGCTGTGCGTGGCAGTTTGCTCAGCCTATCCATTG; GATGGAGCTGCAAGGGGTGAGGACACCAGCATGAACCTTGTTCAGAAATATCTAGAAAAC; TACTACGACCTCGAAAAAGATGTGAAACAGTTTGTTAGGAGAAAGGACAGTGGTCCTGTT; GTTAAAAAAATCCGAGAAATGCAGAAGTTCCTTGGATTGGAGGTGACGGGGAAGCTGGAC; TCCGACACTCTGGAGGTGATGCGCAAGCCCAGGTGTGGAGTTCCTGACGTTGGTCACTTC; AGAACCTTTCCTGGCATCCCGAAGTGGAGGAAAACCCACCTTACATACAGGATTGTGAAT; TATACACCAGATTTGCCAAAAGATGCTGTTGATTCTGCTGTTGAGAAAGCTCTGAAAGTC; TGGGAAGAGGTGACTCCACTCACATTCTCCAGGCTGTATGAAGGAGAGGCTGATATAATG; ATCTCTTTTGCAGTTAGAGAACATGGAGACTTTTACCCTTTTGATGGACCTGGAAATGTT; TTGGCCCATGCCTATGCCCCTGGGCCAGGGATTAATGGAGATGCCCACTTTGATGATGAT; GAACAATGGACAAAGGATACAACAGGGACCAATTTATTTCTCGTTGCTGCTCATGAAATT; GGCCACTCCCTGGGTCTCTTTCACTCAGCCAACACTGAAGCTTTGATGTACCCACTCTAT; CACTCACTCACAGACCTGACTCGGTTCCGCCTGTCTCAAGATGATATAAATGGCATTCAG; TCCCTCTATGGACCTCCCCCTGACTCCCCTGAGACCCCCCTGGTACCCACGGAACCTGTC; CCTCCAGAACCTGGGACGCCAGCCAACTGTGATCCTGCTTTGTCCTTTGATGCTGTCAGC; ACTCTGAGGGGAGAAATCCTGATCTTTAAAGACAGGCACTTTTGGCGCAAATCCCTCAGG; AAGCTTGAACCTGAATTGCATTTGATCTCTTCATTTTGGCCATCTCTTCCTTCAGGCGTG; GATGCCGCATATGAAGTTACTAGCAAGGACCTCGTTTTCATTTTTAAAGGAAATCAATTC; TGGGCCATCAGAGGAAATGAGGTACGAGCTGGATACCCAAGAGGCATCCACACCCTAGGT; TTCCCTCCAACCGTGAGGAAAATCGATGCAGCCATTTCTGATAAGGAAAAGAACAAAACA; TATTTCTTTGTAGAGGACAAATACTGGAGATTTGATGAGAAGAGAAATTCCATGGAGCCA; GGCTTTCCCAAGCAAATAGCTGAAGACTTTCCAGGGATTGACTCAAAGATTGATGCTGTT; TTTGAAGAATTTGGGTTCTTTTATTTCTTTACTGGATCTTCACAGTTGGAGTTTGACCCA; AATGCAAAGAAAGTGACACACACTTTGAAGAGTAACAGCTGGCTTAATTGTTGA; ; Clone variation with respect to NM_002422.3; 133 a=>g;288 t=>c;1086 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002422 unedited; NGGTCAGTCAAATATTTGTAATAGACTCACTATAGGCGGCCGCGNAATTCGCACCAGNAC; AGCAAGGCATAGAGACAACATAGAGCTAAGTAAAGCCAGTGGAAATGAAGAGTCTTCCAA; TCCTACTGTTGCTGTGCGTGGCAGTTTGCTCAGCCTATCCATTGGATGGAGCTGCAAGGG; GTGAGGACACCAGCATGAACCTTGTTCAGAAATATCTAGAAAACTACTACGACCTCGAAA; AAGATGTGAAACAGTTTGTTAGGAGAAAGGACAGTGGTCCTGTTGTTAAAAAAATCCGAG; AAATGCAGAAGTTCCTTGGATTGGAGGTGACGGGGAAGCTGGACTCCGACACTCTGGAGG; TGATGCGCAAGCCCAGGTGTGGAGTTCCTGACGTTGGTCACTTCAGAACCTTTCCTGGCA; TCCCGAAGTGGAGGAAAACCCACCTTACATACAGGATTGTGAATTATACACCAGATTTGC; CAAAAGATGCTGTTGATTCTGCTGTTGAGAAAGCTCTGAAAGTCTGGGAAGAGGTGACTC; CACTCACATTCTCCAGGCTGTATGAAGGAGAGGCTGATATAATGATCTCTTTTGCAGTTA; GAGAACATGGAGACTTTTACCCTTTTGATGGACCTGGAAATGTTTTGGCCCATGCCTATG; CCCCTGGGCCAGGGATTAATGGAGATGCCCACTTTGATGATGATGAACAATGGACAAAGG; ATACAACAGGGACCAATTTATTTCTCGTTGCTGCTCATGAAATTGGCCACTCCCTGGGTC; TCTTTCACTCAGCCAACACTGAAGCTTTGATGTACCCACTCTATCACTCACTCACAGACC; TGACTCGGGTCCGCCTGTCTCAAGAGATATAAAGGC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002422 unedited; TTTCCGGCCAGGAGTTGCACAGAGGAGCCGTCACAGGGATGCCACCCGGGATCTGTTCAG; GAAACAGCTATGACCTGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTAAAA; TAACTGACAAATCGTCTTTATTAAATAAGCAAATAGTCTACACAGATACAGTCACTTGTC; TGTTGCACACGAGTGCTTCCCCTTCTCTTGGGAAAGATCACTCTATGTGACAAGGTGCAA; GCTAAGCAGCAGCCCATTTGAATGCCCTGTAATAACATAAAAATGACCGGCAAGATACAG; ATTCACGCTCAAGTTCCCTTGAGTGTGACTCGAGTCACAGCACAGGCAGGAGAAAACGAA; CATTTCAATTCACAGAGACTTAGGTGAAGAATTATTAGCTTCATTTAAAGTGCCCATATT; GTGCCTTCTACATATCTCTTTCAACAATTAAGCCAGCTGTTACTCTTCAAAGTGTGTGTC; ACTTTCTTTGCATTTGGGTCAAACTCCAACTGTGAAGATCCAGTAAAGAAATAAAAGAAC; CCAAATTCTTCAAAAACAGCATCAATCTTTGAGTCAATCCCTGGAAAGTCTTCAGCTATT; TGCTTGGGAAAGCCTGGCTCCATGGAATTTCTCTTCTCATCAAATCTCCAGTATTTGTCC; TCTACAAAGAAATATGTTTTGTTCTTTTCCTTATCAGAAATGGCTGCATCGATTTTCCT;
• Restriction Sites: Please inquire
• ACCN: NM_002422
• Insert Size: 2300 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002422.3, NP_002413.1
• RefSeq Size: 1828 bp
• RefSeq ORF: 1434 bp
• Locus ID: 4314
• UniProt ID: P08254
• Cytogenetics: 11q22.2
• Protein Families: Druggable Genome, Protease
• Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]