CaMKK (CAMKK1) (NM_172207) Human Untagged Clone

SKU SC123314

CAMKK1 (untagged)-Human calcium/calmodulin-dependent protein kinase kinase 1, alpha (CAMKK1), transcript variant 3

Product Data

• Type: Human Untagged Clone
• Target Symbol: CaMKK
• Synonyms: CAMKKA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_172207 edited; CCGCCCGCCGGGCCGCGGACACTGTCGCCCGGCGCCCAGGTTCCCAACAAGGCTACGCAG; AAGAACCCCCTTGACTGAAGCAATGGAGGGGGGTCCAGCTGTCTGCTGCCAGGATCCTCG; GGCAGAGCTGGTAGAACGGGTGGCAGCCATCGATGTGACTCACTTGGAGGAGGCAGATGG; TGGCCCAGAGCCTACTAGAAACGGTGTGGACCCCCCACCACGGGCCAGAGCTGCCTCTGT; GATCCCTGGCAGTACTTCAAGACTGCTCCCAGCCCGGCCTAGCCTCTCAGCCAGGAAGCT; TTCCCTACAGGAGCGGCCAGCAGGAAGCTATCTGGAGGCGCAGGCTGGGCCTTATGCCAC; GGGGCCTGCCAGCCACATCTCCCCCCGGGCCTGGCGGAGGCCCACCATCGAGTCCCACCA; CGTGGCCATCTCAGATGCAGAGGACTGCGTGCAGCTGAACCAGTACAAGCTGCAGAGTGA; GATTGGCAAGGGTGCCTACGGTGTGGTGAGGCTGGCCTACAACGAAAGTGAAGACAGACA; CTATGCAATGAAAGTCCTTTCCAAAAAGAAGTTACTGAAGCAGTATGGCTTTCCACGTCG; CCCTCCCCCGAGAGGGTCCCAGGCTGCCCAGGGAGGACCAGCCAAGCAGCTGCTGCCCCT; GGAGCGGGTGTACCAGGAGATTGCCATCCTGAAGAAGCTGGACCACGTGAATGTGGTCAA; ACTGATCGAGGTCCTGGATGACCCAGCTGAGGACAACCTCTATTTGGCCCTGCAGAACCA; GGCCCAGAATATCCAGTTAGATTCAACAAATATCGCCAAGCCCCACTCCCTGCTTCCCTC; TGAGCAGCAAGACAGTGGATCCACGTGGGCTGCGCGCTCAGTGTTTGACCTCCTGAGAAA; GGGGCCCGTCATGGAAGTGCCCTGTGACAAGCCCTTCTCGGAGGAGCAAGCTCGCCTCTA; CCTGCGGGACGTCATCCTGGGCCTCGAGTACTTGCACTGCCAGAAGATCGTCCACAGGGA; CATCAAGCCATCCAACCTGCTCCTGGGGGATGATGGGCACGTGAAGATCGCCGACTTTGG; CGTCAGCAACCAGTTTGAGGGGAACGACGCTCAGCTGTCCAGCACGGCGGGAACCCCAGC; ATTCATGGCCCCCGAGGCCATTTCTGATTCCGGCCAGAGCTTCAGTGGGAAGGCCTTGGA; TGTATGGGCCACTGGCGTCACGTTGTACTGCTTTGTCTATGGGAAGTGCCCGTTCATCGA; CGATTTCATCCTGGCCCTCCACAGGAAGATCAAGAATGAGCCCGTGGTGTTTCCTGAGGG; GCCAGAAATCAGCGAGGAGCTCAAGGACCTGATCCTGAAGATGTTAGACAAGAATCCCGA; GACGAGAATTGGGGTGCCAGACATCAAGTTGCACCCTTGGGTGACCAAGAACGGGGAGGA; GCCCCTTCCTTCGGAGGAGGAGCACTGCAGCGTGGTGGAGGTGACAGAGGAGGAGGTTAA; GAACTCAGTCAGGCTCATCCCCAGCTGGACCACGGTGATCCTGGTGAAGTCCATGCTGAG; GAAGCGTTCCTTTGGGAACCCGTTTGAGCCCCAAGCACGGAGGGAAGAGCGATCCATGTC; TGCTCCAGGAAACCTACTGGTGTAAGTACTGGTGGGCCAGGGACTGCCGGGCACTCCCTG; GAGTTGGGTGGGGAGGTCTGAGGCCCATCCTCCCACTCTCACTGTCGTTGGGCCAAGGCC; AGAGCCTGGGGACTTGGCCAGGTCTCGGTGTTGGCCCCATTTGCATCTCTGTCCCCAAGG; TTAGTCGGGGCTAGAAGGGACCTTTTGGGCCCAGCTCTTGCTTCATTCCTGGGGCCAGCA; TCCCTCACACACACACTTCCAGGGATGAGGAGCTCACGCAGCCCCTCCATGGGACAGGAA; GACCCTTCTTCCATGCAGCTTGATGTCACTCTCTCACTGGGTCCAGCCCCTCTGGGGCTT; CAAATCTGTGGCCCCCTCAGCCCTTGGCAGCCTGGCAGAGGTTTGCAGACAGGCTGATGT; TGGCTTCCTGTAGGAGGCTGGCGGGCTGTAGAGGAGGGGTGCTGGCCCCTCTGCCTGGCC; CTGGGGACTGTTGGCTGCTCTCCCAAGTGGCCCAGGCTGCCTGCAGCCATTGCTGGGGCT; CTGCGCCCAGTCAGCACTTTGTGAGTGCTTGTTCAGTGAGTAAGCAGGGACAGGCTGGCC; GGTGGACCACGGGAGAGGAACCCGCATTGGCCGAGGGCTCCCTATGGTGAGCCACGCCTG; TGGGTTCACCACCTCCTAGGAGGGTCCAGAAAAGCAGCTCCCCAAGCCTGTGCGCCTCGT; CCTCAGCAGATCCACCTTCTTCACTATAATAAAAGCCAGTCTGGGATGCTAAAAAAAAAA; AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA; AAAAAAAAA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_172207 unedited; NGGTTTGGATTTGTATACGACTCATATAGGCGGCCGCGNATTCCCGGGATCCGCCCGCCG; GGCCGCGGACACTGTCGCCCGNGCGCCCCAGGTTCCCAACAAGGCTACGCAGAAGAACCC; CCTTGACTGAAGCAATGGAGGGGGGTCCAGCTGTCTGCTGCCAGGATCCTCGGGCAGAGC; TGGTAGAACGGGTGGCAGCCATCGATGTGACTCACTTGGAGGAGGCAGATGGTGGCCCAG; AGCCTACTAGAAACGGTGTGGACCCCCCACCACGGGCCAGAGCTGCCTCTGTGATCCCTG; GCAGTACTTCAAGACTGCTCCCAGCCCGGCCTAGCCTCTCAGCCAGGAAGCTTTCCCTAC; AGGAGCGGCCAGCAGGAAGCTATCTGGAGGCGCAGGCTGGGCCTTATGCCACGGGGCCTG; CCAGCCACATCTCCCCCCGGGCCTGGCGGAGGCCCACCATCGAGTCCCACCACGTGGCCA; TCTCAGATGCAGAGGACTGCGTGCAGCTGAACCAGTACAAGCTGCAGAGTGAGATTGGCA; AGGGTGCCTACGGTGTGGTGAGGCTGGCCTACAACGAAAGTGAAGACAGACACTATGCAA; TGAAAGTCCTTTCCAAAAAGAAGTTACTGAAGCAGTATGGCTTTCCACGTCGCCCTCCCC; CGAGAGGGTCCCAGGCTGCCCAGGGAGGACCAGCCAAGCAGCTGCTGCCCCTGGAGCGGG; TGTACCAGGAGATTGCCATCCTGAAGAAGCTGGACCACGTGAATGTGGTCAAACTGATCG; AGGTCCTGNATGACCCAGCTGNNAGACACCTCTATTGGNCCCTGCAGAAACCAGCCCCAG; ATATCCAGTTAGATTCAACNATATCGCNCAGCCCCACTCCCTGCTTCCNTCTGAGCAGCA; AGACAGTGGATCCACA;
• Restriction Sites: Please inquire
• ACCN: NM_172207
• Insert Size: 2469 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_172207.1, NP_757344.1
• RefSeq Size: 2535 bp
• RefSeq ORF: 1563 bp
• Locus ID: 84254
• UniProt ID: Q8N5S9
• Cytogenetics: 17p13.2
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Adipocytokine signaling pathway
• Summary: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade. Three transcript variants encoding two distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (3) contains an additional segment in the coding region and uses an alternate splice site in the 3' coding region that results in a frameshift, compared to variant 1. It encodes isoform b which is longer, but has a shorter C-terminus compared to isoform a.