GPATCH3 (NM_022078) Human Untagged Clone

CAT#: SC122923

GPATCH3 (untagged)-Human G patch domain containing 3 (GPATCH3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GPATCH3
• Synonyms: GPATC3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_022078 edited
  CCAAGATGGCGGTGCCCGGCGAGGCGGAGGAGGAGGCGACAGTTTACCTGGTAGTGAGCG
  GTATCCCCTCCGTGTTGCGCTCGGCCCATTTACGGAGCTATTTTAGCCAGTTCCGAGAAG
  AGCGCGGCGGTGGCTTCCTCTGTTTCCACTACCGGCATCGGCCTGAGCGGGCCCCTCCGC
  AGGCCGCTCCTAACTCTGCCCTAATTCCTACCGACCCAGCCGCTGAGGGCCAGCTTCTCT
  CTCAGACTTCGGCCACCGATGTCCGGCCTCTCTCCACTCGAGACTCTACTCCAATCCAGA
  CCCGCACCTGCTGCTGCGTCATCTCGGTAAGGGGGTTGGCTCAAGCTCAGAGGCTTATTC
  GCATGTACTCGGGCCGCCGGTGGCTGGATTCTCACGGGACTTGGCTACCGGGTCGCTGTC
  TCATCCGCAGACTTCGGCTACCTACGGAGGCATCAGGTCTGGGCTCCTTTCCCTTCAAGA
  CCCGGAAGGAACTGCAGAGTTGGAAGGCAGAGAATGAAGCCTTCACCCTGGCTGACCTGA
  AGCAACTGCCGGAGCTGAACCCACCAGTGCTGATGCCCAGAGGGAATGTGGGGACTCCCC
  TGCGGGTCTTTTTGGAGTTGATCCGGGCCTGCCGCCTACCCCCTCGGATCATCACCCAGC
  TGCAGCTCCAGTTCCCCAAGACAGGTTCCTCCCGGCGCTACGGCAATGTGCCTTTTGAGT
  ATGAGGACTCAGAGACTGTGGAGCAGGAAGAGCTTGTGTATACAGCAGAGGGTGAAGAAA
  TACCCCAAGGAACCTACCTGGCAGATATACCAGCCAGCCCCTGTGGAGAGCCTGAGGAAG
  AAGTGGGGAAGGAAGAGGAAGAAGAGTCTCACTCAGATGAGGACGATGACCGGGGTGAGG
  AATGGGAACGGCATGAAGCGCTGCATGAGGACGTGACCGGGCAGGAGCGGACCACTGAGC
  AGCTCTTTGAGGAGGAGATTGAGCTCAAGTGGGAGAAGGGTGGCTCTGGCCTGGTGTTTT
  ATACTGATGCCCAGTTCTGGCAGGAGGAAGAAGGAGATTTTGATGAACAGACAGCCGATG
  ACTGGGATGTGGACATGAGTGTGTACTATGACAGAGATGGTGGAGACAAGGATGCCCGAG
  ACTCTGTCCAAATGCGTCTGGAACAGAGACTCCGAGATGGACAGGAAGATGGCTCTGTGA
  TCGAACGCCAGGTGGGCACCTTTGAGCGCCACACCAAGGGCATTGGGCGGAAGGTGATGG
  AGCGGCAGGGCTGGGCTGAGGGCCAGGGCCTGGGCTGCAGGTGCTCAGGGGTGCCTGAGG
  CCCTGGATAGTGATGGCCAACACCCCAGATGCAAGCGTGGATTGGGGTACCATGGAGAGA
  AGCTACAGCCATTTGGGCAACTGAAGAGGCCCCGTAGAAATGGCTTGGGGCTCATCTCCA
  CCATCTATGATGAGCCTCTACCCCAAGACCAGACGGAGTCACTGCTCCGCCGCCAGCCAC
  CCACCAGCATGAAGTTTCGGACAGACATGGCCTTTGTGAGGGGTTCCAGTTGTGCTTCAG
  ACAGCCCCTCATTGCCTGACTGACCGGGTTGGGGGCTTCCTTTCATAGCTACATGATGAA
  AACCCTCTGCCCTGGCCTCATCTACCACTGAAGCAGAAAGGAGTCTGGGAGCAGCAGTCT
  TCGTGGCTGGTTCAGGGTGTTTTGTTCCGAGCCTGCCTGCCTGCCGGTTCTATACCTCAG
  GGGCATTTTTACAAAAAGCCCCCTCCCGTCCCCTCCCCTTGGATATTAGGGGTAACGACC
  GCTTGTCTTTGGTCTCTAACCCTAATCTCTGGGCTTGCCCTTTGCCTCCTGCAGAACTTT
  GAAAAGCTGGGTTGAGTGAGGCTATCAGCACAGCCTTCCTTGGGGACTCTGAAGGTGTCC
  CCACGAAGGCCAGAAAGGGGGAAAGGGACCTGGGCGAGGAGAGGATTTGTGGTGCTTGGA
  AGAGCCGGCCTTGGGTGGGCCCTCCACCGCCTCTACCCTCACTGGGTGGGACTGCCAGCG
  GAGAGTCCGCGGGAGGTGGCTTGGGTGTGCGACGTCACGGAAGAATAAAGACGTTTACTA
  CTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022078 unedited
  NNGGGGGGAGTACAACATTTGTNATACGACTCACTATAGGCGGCCGCGNAATTCGCACNG
  GCCAATAGGCGGTGCCCGGCGAGGCGGAGGAGGAGGCGACAGTTTACCTGGTAGTGAGCG
  GTATCCCCTCCGTGTTGCGCTCGGCCCATTTACGGAGCTATTTTAGCCAGTTCCGAGAAG
  AGCGCGGCGGTGGCTTCCTCTGTTTCCACTACCGGCATCGGCCTGAGCGGGCCCCTCCGC
  AGGCCGCTCCTAACTCTGCCCTAATTCCTACCGACCCAGCCGCTGAGGGCCAGCTTCTCT
  CTCAGACTTCGGCCACCGATGTCCGGCCTCTCTCCACTCGAGACTCTACTCCAATCCAGA
  CCCGCACCTGCTGCTGCGTCATCTCGGTAAGGGGGTTGGCTCAAGCTCAGAGGCTTATTC
  GCATGTACTCGGGCCGCCGGTGGCTGGATTCTCACGGGACTTGGCTACCGGGTCGCTGTC
  TCATCCGCAGACTTCGGCTACCTACGGAGGCATCAGGTCTGGGCTCCTTTCCCTTCAAGA
  CCCGGAAGGAACTGCAGAGTTGGAAGGCAGAGAATGAAGCCTTCACCCTGGCTGACCTGA
  AGCAACTGCCGGAGCTGAACCCACCAGTGCTGATGCCCAGAGGGAATGTGGGGACTCCCC
  TGCGGGTCTTTTTGGAGTTGATCCGGGCCTGCCGCCTACCCCCTCGGATCATCACCCAGC
  TGCAGCTCCAGTTCCCCAAGACAGGTTCCTCCCGGCGCTACGGCAATGTGCCTTTTGAGT
  ATGAGGACTCANAGACTGTGGAGCAGGAAGAGCTTGTGTATACAGCAGAGGGTGAAGGAA
  TACCCC
  
• Restriction Sites: Please inquire
• ACCN: NM_022078
• Insert Size: 2171 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_022078.1, NP_071361.1
• RefSeq Size: 2123 bp
• RefSeq ORF: 1578 bp
• Locus ID: 63906
• UniProt ID: Q96I76
• Cytogenetics: 1p36.11
• Gene Summary: Involved in transcriptional regulation. It is able to activate transcription from the CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development (PubMed:28397860). Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6 (PubMed:28414768).[UniProtKB/Swiss-Prot Function]