GPATCH3 (NM_022078) Human Untagged Clone

SKU SC122923

GPATCH3 (untagged)-Human G patch domain containing 3 (GPATCH3)

Product Data

• Type: Human Untagged Clone
• Target Symbol: GPATCH3
• Synonyms: GPATC3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_022078 edited; CCAAGATGGCGGTGCCCGGCGAGGCGGAGGAGGAGGCGACAGTTTACCTGGTAGTGAGCG; GTATCCCCTCCGTGTTGCGCTCGGCCCATTTACGGAGCTATTTTAGCCAGTTCCGAGAAG; AGCGCGGCGGTGGCTTCCTCTGTTTCCACTACCGGCATCGGCCTGAGCGGGCCCCTCCGC; AGGCCGCTCCTAACTCTGCCCTAATTCCTACCGACCCAGCCGCTGAGGGCCAGCTTCTCT; CTCAGACTTCGGCCACCGATGTCCGGCCTCTCTCCACTCGAGACTCTACTCCAATCCAGA; CCCGCACCTGCTGCTGCGTCATCTCGGTAAGGGGGTTGGCTCAAGCTCAGAGGCTTATTC; GCATGTACTCGGGCCGCCGGTGGCTGGATTCTCACGGGACTTGGCTACCGGGTCGCTGTC; TCATCCGCAGACTTCGGCTACCTACGGAGGCATCAGGTCTGGGCTCCTTTCCCTTCAAGA; CCCGGAAGGAACTGCAGAGTTGGAAGGCAGAGAATGAAGCCTTCACCCTGGCTGACCTGA; AGCAACTGCCGGAGCTGAACCCACCAGTGCTGATGCCCAGAGGGAATGTGGGGACTCCCC; TGCGGGTCTTTTTGGAGTTGATCCGGGCCTGCCGCCTACCCCCTCGGATCATCACCCAGC; TGCAGCTCCAGTTCCCCAAGACAGGTTCCTCCCGGCGCTACGGCAATGTGCCTTTTGAGT; ATGAGGACTCAGAGACTGTGGAGCAGGAAGAGCTTGTGTATACAGCAGAGGGTGAAGAAA; TACCCCAAGGAACCTACCTGGCAGATATACCAGCCAGCCCCTGTGGAGAGCCTGAGGAAG; AAGTGGGGAAGGAAGAGGAAGAAGAGTCTCACTCAGATGAGGACGATGACCGGGGTGAGG; AATGGGAACGGCATGAAGCGCTGCATGAGGACGTGACCGGGCAGGAGCGGACCACTGAGC; AGCTCTTTGAGGAGGAGATTGAGCTCAAGTGGGAGAAGGGTGGCTCTGGCCTGGTGTTTT; ATACTGATGCCCAGTTCTGGCAGGAGGAAGAAGGAGATTTTGATGAACAGACAGCCGATG; ACTGGGATGTGGACATGAGTGTGTACTATGACAGAGATGGTGGAGACAAGGATGCCCGAG; ACTCTGTCCAAATGCGTCTGGAACAGAGACTCCGAGATGGACAGGAAGATGGCTCTGTGA; TCGAACGCCAGGTGGGCACCTTTGAGCGCCACACCAAGGGCATTGGGCGGAAGGTGATGG; AGCGGCAGGGCTGGGCTGAGGGCCAGGGCCTGGGCTGCAGGTGCTCAGGGGTGCCTGAGG; CCCTGGATAGTGATGGCCAACACCCCAGATGCAAGCGTGGATTGGGGTACCATGGAGAGA; AGCTACAGCCATTTGGGCAACTGAAGAGGCCCCGTAGAAATGGCTTGGGGCTCATCTCCA; CCATCTATGATGAGCCTCTACCCCAAGACCAGACGGAGTCACTGCTCCGCCGCCAGCCAC; CCACCAGCATGAAGTTTCGGACAGACATGGCCTTTGTGAGGGGTTCCAGTTGTGCTTCAG; ACAGCCCCTCATTGCCTGACTGACCGGGTTGGGGGCTTCCTTTCATAGCTACATGATGAA; AACCCTCTGCCCTGGCCTCATCTACCACTGAAGCAGAAAGGAGTCTGGGAGCAGCAGTCT; TCGTGGCTGGTTCAGGGTGTTTTGTTCCGAGCCTGCCTGCCTGCCGGTTCTATACCTCAG; GGGCATTTTTACAAAAAGCCCCCTCCCGTCCCCTCCCCTTGGATATTAGGGGTAACGACC; GCTTGTCTTTGGTCTCTAACCCTAATCTCTGGGCTTGCCCTTTGCCTCCTGCAGAACTTT; GAAAAGCTGGGTTGAGTGAGGCTATCAGCACAGCCTTCCTTGGGGACTCTGAAGGTGTCC; CCACGAAGGCCAGAAAGGGGGAAAGGGACCTGGGCGAGGAGAGGATTTGTGGTGCTTGGA; AGAGCCGGCCTTGGGTGGGCCCTCCACCGCCTCTACCCTCACTGGGTGGGACTGCCAGCG; GAGAGTCCGCGGGAGGTGGCTTGGGTGTGCGACGTCACGGAAGAATAAAGACGTTTACTA; CTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA; AA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022078 unedited; NNGGGGGGAGTACAACATTTGTNATACGACTCACTATAGGCGGCCGCGNAATTCGCACNG; GCCAATAGGCGGTGCCCGGCGAGGCGGAGGAGGAGGCGACAGTTTACCTGGTAGTGAGCG; GTATCCCCTCCGTGTTGCGCTCGGCCCATTTACGGAGCTATTTTAGCCAGTTCCGAGAAG; AGCGCGGCGGTGGCTTCCTCTGTTTCCACTACCGGCATCGGCCTGAGCGGGCCCCTCCGC; AGGCCGCTCCTAACTCTGCCCTAATTCCTACCGACCCAGCCGCTGAGGGCCAGCTTCTCT; CTCAGACTTCGGCCACCGATGTCCGGCCTCTCTCCACTCGAGACTCTACTCCAATCCAGA; CCCGCACCTGCTGCTGCGTCATCTCGGTAAGGGGGTTGGCTCAAGCTCAGAGGCTTATTC; GCATGTACTCGGGCCGCCGGTGGCTGGATTCTCACGGGACTTGGCTACCGGGTCGCTGTC; TCATCCGCAGACTTCGGCTACCTACGGAGGCATCAGGTCTGGGCTCCTTTCCCTTCAAGA; CCCGGAAGGAACTGCAGAGTTGGAAGGCAGAGAATGAAGCCTTCACCCTGGCTGACCTGA; AGCAACTGCCGGAGCTGAACCCACCAGTGCTGATGCCCAGAGGGAATGTGGGGACTCCCC; TGCGGGTCTTTTTGGAGTTGATCCGGGCCTGCCGCCTACCCCCTCGGATCATCACCCAGC; TGCAGCTCCAGTTCCCCAAGACAGGTTCCTCCCGGCGCTACGGCAATGTGCCTTTTGAGT; ATGAGGACTCANAGACTGTGGAGCAGGAAGAGCTTGTGTATACAGCAGAGGGTGAAGGAA; TACCCC;
• Restriction Sites: Please inquire
• ACCN: NM_022078
• Insert Size: 2171 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_022078.1, NP_071361.1
• RefSeq Size: 2123 bp
• RefSeq ORF: 1578 bp
• Locus ID: 63906
• UniProt ID: Q96I76
• Cytogenetics: 1p36.11
• Summary: Involved in transcriptional regulation. It is able to activate transcription from the CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development (PubMed:28397860). Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6 (PubMed:28414768).[UniProtKB/Swiss-Prot Function]