CSEN (KCNIP3) (NM_013434) Human Untagged Clone

CAT#: SC122794

KCNIP3 (untagged)-Human Kv channel interacting protein 3, calsenilin (KCNIP3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CSEN
• Synonyms: CSEN; DREAM; KCHIP3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_013434 edited
  GGGAGGCTGGCAACAGTTTTCTTCAGCGCCCAGGATGCAGCCGGCTAAGGAAGTGACAAA
  GGCGTCGGACGGCAGCCTCCTGGGGGACCTCGGGCACACACCACTTAGCAAGAAGGAGGG
  TATCAAGTGGCAGAGGCCGAGGCTCAGCCGCCAGGCTTTGATGAGATGCTGCCTGGTCAA
  GTGGATCCTGTCCAGCACAGCCCCACAGGGCTCAGATAGCAGCGACAGTGAGCTGGAGCT
  GTCCACGGTGCGCCACCAGCCAGAGGGGCTGGACCAGCTGCAGGCCCAGACCAAGTTCAC
  CAAGAAGGAGCTGCAGTCTCTCTACAGGGGCTTTAAGAATGAGTGTCCCACGGGCCTGGT
  GGACGAAGACACCTTCAAACTCATTTACGCGCAGTTCTTCCCTCAGGGAGATGCCACCAC
  CTATGCACACTTCCTCTTCAACGCCTTTGATGCGGACGGGAACGGGGCCATCCACTTTGA
  GGACTTTGTGGTTGGCCTCTCCATCCTGCTGCGGGGCACAGTCCACGAGAAGCTCAAGTG
  GGCCTTTAATCTCTACGACATTAACAAGGATGGCTACATCACCAAAGAGGAGATGCTGGC
  CATCATGAAGTCCATCTATGACATGATGGGCCGCCACACCTACCCCATCCTGCGGGAGGA
  CGCGCCGGCGGAGCACGTGGAGAGGTTCTTCGAGAAAATGGACCGGAACCAGGATGGGGT
  AGTGACCATTGAAGAGTTCCTGGAGGCCTGTCAGAAGGATGAGAACATCATGAGCTCCAT
  GCAGCTGTTTGAGAATGTCATCTAGGACACGTCCAAAGGAGTGCATGGCCACAGCCACCT
  CCACCCCCAAGAAACCTCCATCCTGCCAGGAGCAGCCTCCAAGAAACTTTTAAAAAATAG
  ATTTGCAAAAAGTGAACAGATTGCTACACACACACACACACACACACACACACACACACA
  CACAGCCATTCATCTGGGCTGGCAGAGGGGACAGAGTTCAGGGAGGGGCTGAGTCTGGCT
  AGGGGCCGAGTCCAGGAGCCCCAGCCAGCCCTTCCCAGGCCAGCGAGGCGAGGCTGCCTC
  TGGGTGAGTGGCTGACAGAGCAGGTCTGCAGGCCACCAGCTGCTGGATGTCACCAAGAAG
  GGGCTCGAGTGCCCCTGCAGGGGAGGGTCCAATCTCCGGTGTGAGCCCACCTCGTCCCGT
  TCTCCATTCTGCTTTCTTGCCACACAGTGGGCCGGCCCCAGGCTCCCCTGGTCTCCTCCC
  CGTAGCCACTCTCTGCCCACTACCTATGCTTCTAGAAAGCCCCTCACCTCAGGACCCCAG
  AGGGACCAGCTGGGGGGCAGGGGGGAGAGGGGGTAATGGAGGCCAAGCCTGCAGCTTTCT
  GGAAATTCTTCCCTGGGGGTCCCAGGATCCCCTGCTACTCCACTGACCTGGAAGAGCTGG
  GTACCAGGCCACCCACTGTGGGGCAAGCCTGAGTGGTGAGGGGCCACTGGGCCCCATTCT
  CCCTCCATGGCAGGAAGGCGGGGGATTTCAAGTTTAGGGATTGGGTCGTGGTGGAGAATC
  TGAGGGCACTCTCTGCCAGCTCCACAGGGTGGGATGAGCCTCTCCTTGCCCCAGTCCTGG
  TTCAGTGGGAATGCAGTGGGTGGGGCTGTACACACCCTCCAGCACAGACTGTTCCCTCCA
  AGGTCCTCTTAGGTCCCGGGAGGAACGTGGTTCAGAGACTGGCAGCCAGGGAGCCCGGGG
  CAGAGCTCAGAGGAGTCTGGGAAGGGGCGTGTCCCTCCTCTTCCTGTAGTGCCCCTCCCA
  TGGCCCAGCAGCTTGGCTGAGCCCCCTCTCCTGAAGCAGTGTCGCCGTCCCTCTGCCTTG
  CACAAAAAGCACAAGCATTCCTTAGCAGCTCAGGCGCAGCCCTAGTGGGAGCCCAGCACA
  CTGCTTCTCGGAGGCCAGGCCCTCCTGCTGGCTGAGGCTTGGGCCCAGTAGCCCCAATAT
  GGTGGCCCTGGGGAAGAGGCCTTGGGGGTCTGCTCTGTGCCTGGGATCAGTGGGGCCCCA
  AAGCCCAGCCCGGCTGACCAACATTCAAAAGCACAAACCCTGGGGACTCTGCTTGGCTGT
  CCCCTCCATCTGGGGATGGAGAATGCCAGCCCAAAGCTGGAGCCAATGGTGAGGGCTGAG
  AGGGCTGTGGCTGGGTGGTCAGCAGAAACCCCCAGGAGGAGAGAGATGCTGCTCCCGCCT
  GATTGGGGCCTCACCCAGAAGGAACCCGGTCCCAGGCCGCATGGCCCCTCCAGGAACATT
  CCCACATAATACATTCCATCACAGCCAGCCCAGCTCCACTCAGGGCTGGCCCGGGGAGTC
  CCCGTGTGCCCCAAGAGGCTAGCCCCAGGGTGAGCAGGGCCCTCAGAGGAAAGGCAGTAT
  GGCGGAGGCCATGGGGGCCCCTCGGCATTCACACACAGCCTGGCCTCCCCTGCGGAGCTG
  CATGGACGCCTGGCTCCAGGCTCCAGGCTGACTGGGGGCCTCTGCCTCCAGGAGGGCATC
  AGCTTTCCCTGGCTCAGGGATCTTCTCCCTCCCCTCACCCGCTGCCCAGCCCTCCCAGCT
  GGTGTCACTCTGCCTCTAAGGCCAAGGCCTCAGGAGAGCATCACCACCACACCCCTGCCG
  GCCTTGGCCTTGGGGCCAGACTGGCTGCACAGCCCAACCAGGAGGGGTCTGCCTCCCACG
  CTGGGACACAGACCGGCCGCATGTCTGCATGGCAGAAGCGTCTCCCTTGGCCACGGCCTG
  GGAGGGTGGTTCCTGTTCTCAGCATCCACTAATATTCAGTCCTGTATATTTTAATAAAAT
  AAACTTGACAAAGGAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_013434 unedited
  NGGACGCTCCCATTTGTAATACGACTTACTATAGGCGGCCGCGCATTCCCGGGCTATCGT
  CGACCCACGCGTCCGGGGAGGCTGGCAACAGTTTTCTTCAGCGCCCAGGATGCAGCCGGC
  TAAGGAAGTGACAAAGGCGTCGGACGGCAGCCTCCTGGGGGACCTCGGGCACACACCACT
  TAGCAAGAAGGAGGGTATCAAGTGGCAGAGGCCGAGGCTCAGCCGCCAGGCTTTGATGAG
  ATGCTGCCTGGTCAAGTGGATCCTGTCCAGCACAGCCCCACAGGGCTCAGATAGCAGCGA
  CAGTGAGCTGGAGCTGTCCACGGTGCGCCACCAGCCAGAGGGGCTGGACCAGCTGCAGGC
  CCAGACCAAGTTCACCAAGAAGGAGCTGCAGTCTCTCTACAGGGGCTTTAAGAATGAGTG
  TCCCACGGGCCTGGTGGACGAAGACACCTTCAAACTCATTTACGCGCAGTTCTTCCCTCA
  GGGAGATGCCACCACCTATGCACACTTCCTCTTCAACGCCTTTGATGCGGACGGGAACGG
  GGCCATCCACTTTGAGGACTTTGTGGTTGGCCTCTCCATCCTGCTGCGGGGCACAGTCCA
  CGAGAAGCTCAAGTGGGCCTTTAATCTCTACGACATTAACAAGGATGGCTACATCACCAA
  AGAGGAGATGCTGGCCATCATGAAGTCCATCTATGACATGATGGGCCGCCACACCTACCC
  CATCCTGCGGGAGGACGCGCCGGCGGAGCACGTGGAGAGGTTCTTCCAGAAAATGGACCG
  GACCAGGAGGGGTAGTGACCATTGAAGAGTTCCTGGAGCCTGTCAAAAGGTGAGACATCA
  TGAGCTCCATGCACCTGTTGGAGATGTCATCTAGGACACGTCCCAAGGATGCC
  
• Restriction Sites: Please inquire
• ACCN: NM_013434
• Insert Size: 2849 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_013434.3, NP_038462.1
• RefSeq Size: 2906 bp
• RefSeq ORF: 771 bp
• Locus ID: 30818
• UniProt ID: Q9Y2W7
• Cytogenetics: 2q11.1
• Protein Families: Druggable Genome, Transcription Factors, Transmembrane
• Gene Summary: This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).