Prolactin (PRL) (NM_000948) Human Untagged Clone

SKU SC122581

PRL (untagged)-Human prolactin (PRL), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: Prolactin
• Synonyms: GHA1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000948 edited; GGGATCCTTATTCTATATCTCTTGGTATTTAGTGTAAAAATTTTAAAATCTTTACCTAGC; AATCTTGAGGAAGAAACTTGATAACTGATAATACATGAGATTGTTACCTAAGTGAAATAT; AATCCTATATATTCAACAAACTTTAGAGAAATAAGATAAATTTTAAAGTAAATGACTTCT; GTAGTTTTATAGATCCTCCAAACCAATCTAGTCTCAGATCTCACCTTCATCATTTCTCTC; ATTTCCTTTTGGCCTAATTAATCAAAATCCTTCCTAGAATGTTCATTTCTGGCCAGTATG; TCTTCCTGAATATGAATAAGAAATAAAATACCATTTGATGTTTGAAATTATGGGGGTAAT; CTCAATGACGGAAATAGATGACCAGGAAAAGGGAAACGAATGCCTGATTCATTATATTCA; TGAAGATATCAAAGGTTTATAAAGCCAATATCTGGGAAAGAGAAAACCGTGAGACTTCCA; GATCTTCTCTGGTGAAGTGTGTTTCCTGCAACGATCACGAACATGAACATCAAAGGATCG; CCATGGAAAGGGTCCCTCCTGCTGCTGCTGGTGTCAAACCTGCTCCTGTGCCAGAGCGTG; GCCCCCTTGCCCATCTGTCCCGGCGGGGCTGCCCGATGCCAGGTGACCCTTCGAGACCTG; TTTGACCGCGCCGTCGTCCTGTCCCACTACATCCATAACCTCTCCTCAGAAATGTTCAGC; GAATTCGATAAACGGTATACCCATGGCCGGGGGTTCATTACCAAGGCCATCAACAGCTGC; CACACTTCTTCCCTTGCCACCCCCGAAGACAAGGAGCAAGCCCAACAGATGAATCAAAAA; GACTTTCTGAGCCTGATAGTCAGCATATTGCGATCCTGGAATGAGCCTCTGTATCATCTG; GTCACGGAAGTACGTGGTATGCAAGAAGCCCCGGAGGCTATCCTATCCAAAGCTGTAGAG; ATTGAGGAGCAAACCAAACGGCTTCTAGAGGGCATGGAGCTGATAGTCAGCCAGGTTCAT; CCTGAAACCAAAGAAAATGAGATCTACCCTGTCTGGTCGGGACTTCCATCCCTGCAGATG; GCTGATGAAGAGTCTCGCCTTTCTGCTTATTATAACCTGCTCCACTGCCTACGCAGGGAT; TCACATAAAATCGACAATTATCTCAAGCTCCTGAAGTGCCGAATCATCCACAACAACAAC; TGCTAAGCCCACATCCATTTCATCTATTTCTGAGAAGGTCCTTAATGATCCGTTCCATTG; CAAGCTTCTTTTAGTTGTATCTCTTTTGAATCCATGCTTGGGTGTAACAGGTCTCCTCTT; AAAAAATAAAAACTGACTCCTTAGAGACATCAAAATCCAAAAAAAAAAAAAAAAAAAAAA; AAAAAAAA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000948 unedited; CGTCANAATTTGTATACGACTCATATAGGGCGGCCGCGAATCGGCCATTACGGCCGGGAT; CCTTATTCTATATCTCTTGGTATTTAGTGTAAAAATTTTAAAATCTTTACCTAGCAATCT; TGAGGAAGAAACTTGATAACTGATAATACATGAGATTGTTACCTAAGTGAAATATAATCC; TATATATTCAACAAACTTTAGAGAAATAAGATAAATTTTAAAGTAAATGACTTCTGTAGT; TTTATAGATCCTCCAAACCAATCTAGTCTCAGATCTCACCTTCATCATTTCTCTCATTTC; CTTTTGGCCTAATTAATCAAAATCCTTCCTAGAATGTTCATTTCTGGCCAGTATGTCTTC; CTGAATATGAATAAGAAATAAAATACCATTTGATGTTTGAAATTATGGGGGTAATCTCAA; TGACGGAAATAGATGACCAGGAAAAGGGAAACGAATGCCTGATTCATTATATTCATGAAG; ATATCAAAGGTTTATAAAGCCAATATCTGGGAAAGAGAAAACCGTGAGACTTCCAGATCT; TCTCTGGTGAAGTGTGTTTCCTGCAACGATCACGAACATGAACATCAAAGGATCGCCATG; GAAAGGGTCCCTCCTGCTGCTGCTGGTGTCAAACCTGCTCCTGTGCCAGAGCGTGGCCCC; CTTGCCCATCTGTCCCGGCGGNGCTGCCCGATGCCAGGTGACCCTTCGAGACCTGTTTGA; CCGCGCCGTCGTCCTGTCCCACTACATCCATAACCTCTCCTCAGAAATGTTCAGCGAATT; CGATAAACGGTATACCCATGGGCCGGGGGTTCATTACCAAGGCCATCAACAGCTGCCACA; CTTTCTCCCCTTGCCACCCCCGAAGAACAGGAGCAAGCCCAACAGATGAATCAAAAAGAC; TTTCTGAGCCTGATAGTCAGCATATTGCGATCCTG;
• Restriction Sites: Please inquire
• ACCN: NM_000948
• Insert Size: 1400 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000948.2, NP_000939.1
• RefSeq Size: 1388 bp
• RefSeq ORF: 684 bp
• Locus ID: 5617
• UniProt ID: P01236
• Cytogenetics: 6p22.3
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction
• Summary: This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]; Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.