SHC4 (NM_203349) Human Untagged Clone

SKU SC121449

SHC4 (untagged)-Human SHC (Src homology 2 domain containing) family, member 4 (SHC4)

Product Data

• Type: Human Untagged Clone
• Target Symbol: SHC4
• Synonyms: RaLP; SHCD
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_203349, the custom clone sequence may differ by one or more nucleotides; ; ; ATGCGAGAACGCGGCCAGGACAGCCTGGCAGGACTCGTGCTGTATGTAGGACTCTTCGGGCACCCCGGGA; TGCTGCACAGGGCCAAGTACAGCCGCTTTCGGAACGAGTCGATCACGTCCTTGGACGAAGGTAGCTCCGG; AGGCTCGGTCGGGAACAAGGGCTCGCCGCAGCCTCCCCACCCCGCCCTGGCACCTCACCTGCCGACTGAA; GATGCCACCTTGCCGTCGCAGGAGAGCCCCACCCCACTGTGCACCTTGATCCCCCGCATGGCAAGCATGA; AGCTGGCCAACCCGGCCACTTTGCTGAGTCTGAAAAACTTTTGCCTGGGTACCAAAGAGGTGCCTCGGCT; GAAGCTCCAGGAAAGCCGGGACCCAGGTTCCAGCGGCCCCTCTTCCCCAGAAACCAGTTTAAGTAGGTCC; GGGACTGCACCTCCACCGCAGCAGGACCTGGTGGGACACAGGGCAACCGCCCTAACCCCTGATTCGTGCC; CGCTTCCTGGCCCTGGGGAGCCAACACTTAGGAGCAGGCAGGACAGGCACTTTCTACAGCACCTGTTGGG; GATGGGCATGAACTACTGTGTGAGGTACATGGGCTGTGTTGAAGTGCTGCAATCAATGAGATCACTGGAT; TTTGGAATGAGAACCCAAGTTACAAGGGAAGCAATAAGTCGCCTGTGTGAAGCTGTCCCCGGGGCAAATG; GAGCCATTAAAAAGCGAAAGCCTCCAGTTAAGTTCCTATCAACAGTCCTTGGCAAAAGTAATCTTCAGTT; TTCAGGAATGAATATAAAACTGACCATCTCAACATGCAGTCTCACATTGATGAATCTTGACAACCAACAG; ATTATTGCAAATCATCATATGCAGTCTATTTCATTTGCCTCTGGAGGGGATCCTGATACTACAGACTATG; TTGCCTACGTAGCTAAAGATCCAGTTAATCAACGAGCCTGTCACATATTGGAATGCCACAATGGAATGGC; CCAAGACGTCATAAGTACCATAGGGCAGGCTTTTGAACTCCGGTTTAAACAGTACTTGAAAAATCCTTCT; TTGAATACTTCTTGTGAAAGTGAGGAGGTGCATATTGATAGCCATGCCGAGGAGAGAGAAGATCATGAAT; ATTACAATGAAATTCCAGGGAAGCAGCCACCAGTAGGTGGTGTTTCAGATATGCGGATCAAAGTTCAAGC; CACGGAACAAATGGCTTACTGCCCCATACAGTGTGAAAAGTTGTGCTATTTGCCTGGAAACTCCAAGTGC; AGCAGTGTATATGAGAACTGTTTAGAACAAAGCAGGGCAATAGGTAATGTCCATCCAAGAGGGGTGCAGT; CCCAGCGAGATACCTCATTATTGAAGCACACGTGCCGAGTGGATCTCTTTGATGACCCCTGCTACATTAA; TACACAGGCTCTTCAAAGTACACCTGGCTCTGCTGGAAATCAAAGGTCAGCCCAACCACTGGGGAGCCCA; TGGCACTGCGGAAAGGCACCAGAAACTGTTCAGCCGGGTGCCACAGCCCAGCCTGCCAGCTCACATTCTT; TGCCACACATTAAGCAGCAGCTGTGGAGCGAAGAATGCTATCATGGCAAGCTGAGCAGGAAGGCGGCAGA; GAGCCTCTTGGTAAAGGATGGGGACTTTTTGGTTCGAGAGAGTGCAACATCCCCTGGCCAATATGTGCTG; AGTGGACTACAGGGAGGCCAAGCAAAACATCTTCTCCTGGTGGATCCTGAAGGCAAGGTGAGGACCAAGG; ATCATGTATTTGATAATGTCGGCCACCTTATCAGATACCATATGGATAACAGTTTGCCAATCATCTCCTC; TGGAAGCGAAGTAAGCCTTAAACAACCAGTGAGAAAAGATAATAATCCAGCACTTTTGCATTCCAACAAA; TGA; ;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_203349 unedited; TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCGGGAGCCGAGGTGG; GCGAGCTCGAGAGCAGAGTTGGAGAGGTGGCTGCTGTGAGTTGCATCGGGCGTTGAGGTA; TCTGATGTCTGCACCGTTTATCTACCAGACGACGAGGCGATTTATGCAACAGTATCCTGT; TTCAGCACTGCCAAGGCTATGCGAGAACGCGGCCAGGACAGCCTGGCAGGACTCGTGCTG; TATGTAGGACTCTTCGGGCACCCCGGGATGCTGCACAGGGCCAAGTACAGCCGCTTTCGG; AACGAGTCGATCACGTCCTTGGACGAAGGTAGCTCCGGAGGCTCGGTCGGGAACAAGGGC; TCGCCGCAGCCTCCCCACCCCGCCCTGGCACCTCACCTGCCGACTGAAGATGCCACCTTG; CCGTCGCAGGAGAGCCCCACCCCACTGTGCACCTTGATCCCCCGCATGGCAAGCATGAAG; CTGGCCAACCCGGCCACTTTGCTGAGTCTGAAAAACTTTTGCCTGAGTACCAAAGAGGTG; CCTCGGCTGAAGCTCCAGGAAAGCCGGGACCCAGGTTCCAGCGGCCCCTCTTCCCCAGAA; ACCAGTTTAAGTAGGTCCGGGACTGCACCTCCACCGCAGCAGGACCTGGTGGGACACAGG; NCAACCGCCCTAACCCCTGATTCGTGCCCGCTTCCTGGCCCTGNGGAGCCAACACTTANG; AGCAGGCAGGACAGGCACTTTCTACAGCACCTGTTGGGGATGGGCATGAACTACTGTGTG; AGGTACATGGGNCTGTGNNTGAANTGCTGCAATCAATGAAATCACTGGNATTTTGGAATG; AGAACCCAANGTACAGGGNAAGCAATNAGTCGCCTGTGTGAAACTGTCCCCGGGCAAATG;
• Restriction Sites: NotI-NotI
• ACCN: NM_203349
• Insert Size: 1600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_203349.2, NP_976224.2
• RefSeq Size: 4563 bp
• RefSeq ORF: 1893 bp
• Locus ID: 399694
• UniProt ID: Q6S5L8
• Cytogenetics: 15q21.1
• Protein Pathways: Chemokine signaling pathway, Chronic myeloid leukemia, ErbB signaling pathway, Focal adhesion, Glioma, Insulin signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway
• Summary: Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.[UniProtKB/Swiss-Prot Function]