NRP2 (NM_003872) Human Untagged Clone

SKU SC121198

NRP2 (untagged)-Human neuropilin 2 (NRP2), transcript variant 2

Product Data

• Type: Human Untagged Clone
• Target Symbol: NRP2
• Synonyms: NP2; NPN2; PRO2714; VEGF165R2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC121198 sequence for NM_003872 edited (data generated by NextGen Sequencing); ATGGATATGTTTCCTCTCACCTGGGTTTTCTTAGCCCTCTACTTTTCAAGACACCAAGTG; AGAGGCCAACCAGACCCACCGTGCGGAGGTCGTTTGAATTCCAAAGATGCTGGCTATATC; ACCTCTCCCGGTTACCCCCAGGACTACCCCTCCCACCAGAACTGCGAGTGGATTGTTTAC; GCCCCCGAACCCAACCAGAAGATTGTCCTCAACTTCAACCCTCACTTTGAAATCGAGAAG; CACGACTGCAAGTATGACTTTATCGAGATTCGGGATGGGGACAGTGAATCCGCAGACCTC; CTGGGCAAACACTGTGGGAACATCGCCCCGCCCACCATCATCTCCTCGGGCTCCATGCTC; TACATCAAGTTCACCTCCGACTACGCCCGGCAGGGGGCAGGCTTCTCTCTGCGCTACGAG; ATCTTCAAGACAGGCTCTGAAGATTGCTCAAAAAACTTCACAAGCCCCAACGGGACCATC; GAATCTCCTGGGTTTCCTGAGAAGTATCCACACAACTTGGACTGCACCTTTACCATCCTG; GCCAAACCCAAGATGGAGATCATCCTGCAGTTCCTGATCTTTGACCTGGAGCATGACCCT; TTGCAGGTGGGAGAGGGGGACTGCAAGTACGATTGGCTGGACATCTGGGATGGCATTCCA; CATGTTGGCCCCCTGATTGGCAAGTACTGTGGGACCAAAACACCCTCTGAACTTCGTTCA; TCGACGGGGATCCTCTCCCTGACCTTTCACACGGACATGGCGGTGGCCAAGGATGGCTTC; TCTGCGCGTTACTACCTGGTCCACCAAGAGCCACTAGAGAACTTTCAGTGCAATGTTCCT; CTGGGCATGGAGTCTGGCCGGATTGCTAATGAACAGATCAGTGCCTCATCTACCTACTCT; GATGGGAGGTGGACCCCTCAACAAAGCCGGCTCCATGGTGATGACAATGGCTGGACCCCC; AACTTGGATTCCAACAAGGAGTATCTCCAGGTGGACCTGCGCTTTTTAACCATGCTCACG; GCCATCGCAACACAGGGAGCGATTTCCAGGGAAACACAGAATGGCTACTACGTCAAATCC; TACAAGCTGGAAGTCAGCACTAATGGAGAGGACTGGATGGTGTACCGGCATGGCAAAAAC; CACAAGGTATTTCAAGCCAACAACGATGCAACTGAGGTGGTTCTGAACAAGCTCCACGCT; CCACTGCTGACAAGGTTTGTTAGAATCCGCCCTCAGACCTGGCACTCAGGTATCGCCCTC; CGGCTGGAGCTCTTCGGCTGCCGGGTCACAGATGCTCCCTGCTCCAACATGCTGGGGATG; CTCTCAGGCCTCATTGCAGACTCCCAGATCTCCGCCTCTTCCACCCAGGAATACCTCTGG; AGCCCCAGTGCAGCCCGCCTGGTCAGCAGCCGCTCGGGCTGGTTCCCTCGAATCCCTCAG; GCCCAGCCCGGTGAGGAGTGGCTTCAGGTAGATCTGGGAACACCCAAGACAGTGAAAGGT; GTCATCATCCAGGGAGCCCGCGGAGGAGACAGTATCACTGCTGTGGAAGCCAGAGCATTT; GTGCGCAAGTTCAAAGTCTCCTACAGCCTAAACGGCAAGGACTGGGAATACATTCAGGAC; CCCAGGACCCAGCAGCCAAAGCTGTTCGAAGGGAACATGCACTATGACACCCCGGACATC; CGAAGGTTTGACCCCATTCCGGCACAGTATGTGCGGGTATACCCGGAGAGGTGGTCGCCG; GCGGGGATTGGGATGCGGCTGGAGGTGCTGGGCTGTGACTGGACAGACTCCAAGCCCACG; GTAGAGACGCTGGGACCCACTGTGAAGAGCGAAGAGACAACCACCCCCTACCCCACCGAA; GAGGAGGCCACAGAGTGTGGGGAGAACTGCAGCTTTGAGGATGACAAAGATTTGCAGCTC; CCTTCGGGATTCAATTGCAACTTCGATTTCCTCGAGGAGCCCTGTGGTTGGATGTATGAC; CATGCCAAGTGGCTCCGGACCACCTGGGCCAGCAGCTCCAGCCCAAACGACCGGACGTTT; CCAGATGACAGGAATTTCTTGCGGCTGCAGAGTGACAGCCAGAGAGAGGGCCAGTATGCC; CGGCTCATCAGCCCCCCTGTCCACCTGCCCCGAAGCCCGGTGTGCATGGAGTTCCAGTAC; CAGGCCACGGGCGGCCGCGGGGTGGCGCTGCAGGTGGTGCGGGAAGCCAGCCAGGAGAGC; AAGTTGCTGTGGGTCATCCGTGAGGACCAGGGCGGCGAGTGGAAGCACGGGCGGATCATC; CTGCCCAGCTACGACATGGAGTACCAGATTGTGTTCGAGGGAGTGATAGGGAAAGGACGT; TCCGGAGAGATTGCCATTGATGACATTCGGATAAGCACTGATGTCCCACTGGAGAACTGC; ATGGAACCCATCTCGGCTTTTGCAGTGGACATCCCAGAAATACATGAGAGAGAAGGATAT; GAAGATGAAATTGATGATGAATACGAGGTGGACTGGAGCAATTCTTCTTCTGCAACCTCA; GGGTCTGGCGCCCCCTCGACCGACAAAGAAAAGAGCTGGCTGTACACCCTGGATCCCATC; CTCATCACCATCATCGCCATGAGCTCACTGGGCGTCCTCCTGGGGGCCACCTGTGCAGGC; CTCCTGCTCTACTGCACCTGTTCCTACTCGGGCCTGAGCTCCCGAAGCTGCACCACACTG; GAGAACTACAACTTCGAGCTCTACGATGGCCTTAAGCACAAGGTCAAGATGAACCACCAA; AAGTGCTGCTCCGAGGCATGA; ; Clone variation with respect to NM_003872.2; 1071 t=>c;1674 t=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003872 unedited; CCGCGGAATCGGCACGAGGCACCAGCCTGCAGCCGGCCCCCAGCACATCCTCAGCCGCAC; AGACACTCGGCGAGGTGGAGGTGAGGGCGGGCGCCAGCGAACTCGGAGAGGGGCTCGCTC; ACTCCCAGGCGATCCCAGCCGCCACCGCCGCCGCACCAGCAGCAGCAACAGCAGCAGCAG; CTTCCTTCCTCAGACTCCCCTCGAGAGGCTGGCCAAGCGGGTGTAGCCGTTGGGGGAGGC; TCCCGCCGGGGGAACCCGGCGAGGACAAGAGCAGGGCGGCCGCCTTCCACTCGGGCTGTC; CGGCGGCGGCTGCCTCCGCCCGCGTGTCCGTCAAGGGTGCCGCGGGATGTGTGTCAGTTT; ACGCCTCTGAGATCACACAGCTGCCTGGGGGCCGTGTGATGCCCAAGGCAAGTCTTGGTT; TTAATTATTATTATTATCATTATTGTTACGCTTGGCTTTCGGGAAATACTCGTGATATTT; GTAGGATAAAGGAAATGACACTTTGAGGAACTGGAGAGAACATATATGCGTTTTGTTTTT; AAGAGGAAAACCGTGTTCTCTTCCCGGCTTGTTCCCTCTTTGCTGATTTCAGGAGCTACT; CTCCTCCTGGTGAGGTGGAAATTCCAGCAAGAATAGAGGTGAAGACAAGCCACCAGGACT; CAGGAGGGAAACGCTGACCATTAGAAACCTCTGCATAAGACGTTGTAAGGAGGAAAATAA; TAGAGAGAAGAACACATAGATTTAAACAAGAAACCTACGAACCCAGCTCTGGAAAGAGCC; ACCTTCTNCAAATGGATATGTTTCCTCTCACCTGGGATGTCTAGCCCTCTACTTTTCAGA; CACCAGTGAGAGGCCACCAGACCCACGTGCGGNAGTCGNTTGAATCC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003872 unedited; NGACTTTTGTGGTTGTTTATCCAATTTTAATCTTAAAAGGCTTTATACAAATCATATAAA; CACAGTTTGACATTGTTGTTTATTTTTTAACATTGAAGAATCACAGTAAAAGCTCTCAAG; TTCCCGTGATCTGGCTCAGCCAGTGAATGGTCGAATACCTCTAACTGCAAACCCTGAAAA; AGTTAACCTGCTATGTGACAGGTTAACTCTTTCCCTTGTTTTCTTGTCATTCATGCTTAT; TCCTTGGACCCTCATCCCTGTCAACTCCCCTGCCCCACCAAAGACAGAAAGCAACCCTGT; GGCCCTGTTGACCACCTAGTCCGGGAGAGTGTGGAGGTAATGTGTCATTCAGTACAAGGC; AAAAAGGAGATCAATACTGGCAGTGGGGTTTCCCAAAGGGAATGACTCAAGGAGATGGGT; CAGCTAGCCTACCCACAGATAAAGATAACAAACACACCAAGGTGTCCCCTGGCCAAGTCA; AAATTGGGCCCAGCGTCTTTCTTTCTGTCTTACGACAGAGCAGCCTCCAGCCTTGGTGTG; GTATCTACATGTAGCCCTCCGTACCCTGCTTCTTTTTAGCATTCAAGGCCCACTCAGGGC; CTCAAATTAGCCAATGGTGAATATGGATATAGGACTTTTAGAGGGATGCAGGTTGAGTTG; TACATAACTTATAGGTGAAGTGCAAGTCCGAAACAGGGCTAGACTTTGGAGAACTGGTAA; ATGGCTCACTGAGCATGACAGCATCAGGGACCCCTGAGAGTGGCTTTCAAAACTTACCTT; CCTTTTGCAAGCTACCTTCTGGGAAAATCGCTAAGGACTTACCCAGCCTTTCTGAACACT; GTCGCATCATGGGTAGTGTGAAGAGGAAAAGGGGCCTAGTTAAATACTTGCTTCTACTGT; GGGCCGCAACTCAGGAAGGAGCCCTATAACCTAATCCCTTGGGCC;
• Restriction Sites: NotI-NotI
• ACCN: NM_003872
• Insert Size: 6550 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003872.2, NP_003863.2
• RefSeq Size: 6656 bp
• RefSeq ORF: 2781 bp
• Locus ID: 8828
• UniProt ID: O60462
• Cytogenetics: 2q33.3
• Protein Families: Druggable Genome, Transmembrane
• Summary: This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (2), also known as NRP2a(17), lacks an alternate in-frame segment, compared to variant 1. This results in a shorter isoform (2), compared to isoform 1.