FKBP2 (NM_057092) Human Untagged Clone

SKU SC120228

FKBP2 (untagged)-Human FK506 binding protein 2, 13kDa (FKBP2), transcript variant 2

Product Data

• Type: Human Untagged Clone
• Target Symbol: FKBP2
• Synonyms: FKBP-13; FKBP13; PPIase
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC120228 sequence for NM_057092 edited (data generated by NextGen Sequencing); ATGAGGCTGAGCTGGTTCCGGGTCCTGACAGTACTGTCCATCTGCCTGAGCGCCGTGGCC; ACGGCCACGGGGGCCGAGGGCAAAAGGAAGCTGCAGATCGGGGTCAAGAAGCGGGTGGAC; CACTGTCCCATCAAATCGCGCAAAGGGGATGTCCTGCACATGCACTACACGGGGAAGCTG; GAAGATGGGACAGAGTTTGACAGCAGCCTGCCCCAGAACCAGCCCTTTGTCTTCTCCCTT; GGCACAGGCCAGGTCATCAAGGGCTGGGACCAGGGGCTGCTGGGGATGTGTGAGGGGGAA; AAGCGCAAGCTGGTGATCCCATCCGAGCTAGGGTATGGAGAGCGGGGAGCTCCCCCAAAG; ATTCCAGGCGGTGCAACCCTGGTGTTCGAGGTGGAGCTGCTCAAAATAGAGCGACGAACT; GAGCTGTAA; ; Clone variation with respect to NM_057092.2;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_057092 unedited; GGGGCGCGAATTCGGCACCAGGAGACATGAGGCTGAGCTGGTTCCGGGTCCTGACAGTAC; TGTCCATCTGCCTGAGCGCCGTGGCCACGGCCACGGGGGCCGAGGGCAAAAGGAAGCTGC; AGATCGGGGTCAAGAAGCGGGTGGACCACTGTCCCATCAAATCGCGCAAAGGGGATGTCC; TGCACATGCACTACACGGGGAAGCTGGAAGATGGGACAGAGTTTGACAGCAGCCTGCCCC; AGAACCAGCCCTTTGTCTTCTCCCTTGGCACAGGCCAGGTCATCAAGGGCTGGGACCANG; GGCTGCTGGGGATGTGTGAGGGGGAAAAGCGCAAGCTGGTGATCCCATCCGAGCTAGGGT; ATGGAGAGCGGGGAGCTCCCCCAAAGATTCCAGGCGGTGCAACCCTGGTGTTCGAGGTGG; AGCTGCTCAAAATAGAGCGACGAACTGAGCTGTAACCAGACTGGGGAGGGGCAGGGGGAG; AGGCCCCCATCAGGGACCAGACTGTTCCAAAAAAAAAACAAAAACAAAAACAACAAAAAA; ACACTTAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGNCGCGGCATAGCTGGTTCT; GAACAATCCCCGGTGGGATNCCTGTGACCCCTCCCAGTGCCTCTCTGGCCCTGGAAGGTG; CACTCCAGTGCCACCAGCCTTGGCTATAAAATTAAGTGATCATTTGCGACTAGGTGCTCT; ATTGGGGGGGGGGGGG;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_057092 unedited; ACCCCCCCCACCAAAAAAAANAACCACACCAATCCCACACCNNNANNTTTTGACTTTGNN; ACCGCGGCCCCGCATTCTNANGATCGAGTTTTTTTTTTTTTTTTTTAATGTTTTTTTGTT; TGTTTTTGTTTTTTGTTTTTTTTTTTGGAACAGTCTGGTCCCTGATGGGGGCCTCTCCCC; CTGCCCCTCCCCAGTCTGGTTACAGCTCAGTTCGTCGCTCTATTTTGAGCAGCTCCACCT; CGAACACCAGGGTTGCACCGCCTGGAATCTTTGGGGGAGCTCCCCGCTCTCCATACCCTA; GCTCGGATGGGATCACCAGCTTGCGCTTTTCCCCCTCACACATCCCCAGCAGCCCCTGGT; CCCAGCCCTTGATGACCTGGCCTGTGCCAAGGGAGAAGACAAAGGGCTGGTTCTGGGGCA; GGCTGCTGTCAAACTCTGTCCCATCTTCCAGCTTCCCCGTGTAGTGCATGTGCAGGACAT; CCCCTTTGCGCGATTTGATGGGACAGTGGTCCACCCGCTTCTTGACCCCGATCTGCAGCT; TCCTTTTGCCCTCGGCCCCCGTGGCCGTGGCCACGGCGCTCAGGCAGATGGACAGTACTG; TCAGGACCCGGAACCAGCTCAGCCTCATGTCTCCTGGTGCCGAATTCCCGGCCGCCCTAT; AGTGAGTCGTATTACAAAATTCTGACGGTTCACTAAACGAGCTCTGCTTATATAGACCTC; CCACCGTACACGCCTACCGCCCATTTGCGTCACGGGGGTGGGGTTATTACCACATTTTTG; GAAAGTCCCGGTTGATTTTGGGGCCAAAACCAAACTCCCATTGACCGTCAATGGGGGGTG; GAAGACTTGGAAAACCCCTGGGAGTAAAACCCGCTTTCCCCTGCCCAATTGGCGTAATTT; GCCAAACCCTTTTAACCCATGGTAATACCCGATAATTAA;
• Restriction Sites: NotI-NotI
• ACCN: NM_057092
• Insert Size: 550 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_057092.1, NP_476433.1
• RefSeq Size: 714 bp
• RefSeq ORF: 429 bp
• Locus ID: 2286
• UniProt ID: P26885
• Cytogenetics: 11q13.1
• Domains: FKBP
• Protein Families: Druggable Genome
• Summary: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]; Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 through 6 encode the same isoform.