Protein C inhibitor (SERPINA5) (NM_000624) Human Untagged Clone

SKU SC119795

SERPINA5 (untagged)-Human serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 (SERPINA5)

Product Data

• Type: Human Untagged Clone
• Target Symbol: Protein C inhibitor
• Synonyms: PAI-3; PAI3; PCI; PCI-B; PLANH3; PROCI
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119795 sequence for NM_000624 edited (data generated by NextGen Sequencing); ATGCAGCTCTTCCTCCTCTTGTGCCTGGTGCTTCTCAGCCCTCAGGGGGCCTCCCTTCAC; CGCCACCACCCCCGGGAGATGAAGAAGAGAGTCGAGGACCTCCATGTAGGTGCCACGGTG; GCCCCCAGCAGCAGAAGGGACTTTACCTTTGACCTCTACAGGGCCTTGGCTTCCGCTGCC; CCCAGCCAGAGCATCTTCTTCTCCCCTGTGAGCATCTCCATGAGCCTGGCCATGCTCTCC; CTGGGGGCTGGGTCCAGCACAAAGATGCAGATCCTGGAGGGCCTGGGCCTAAACCTCCAG; AAAAGCTCAGAGAAGGAGCTGCACAGAGGCTTTCAGCAGCTCCTTCAGGAACTCAACCAG; CCCAGAGATGGCTTCCAGCTGAGCCTCGGCAATGCCCTTTTCACCGACCTGGTGGTAGAC; CTGCAGGACACCTTCGTAAGTGCCATGAAGACGCTGTACCTGGCAGACACTTTCCCTACC; AACTTTAGGGACTCTGCAGGGGCCATGAAGCAGATCAATGATTATGTGGCAAAGCAAACG; AAGGGCAAGATTGTGGACTTGCTTAAGAACCTCGATAGCAATGCGGTCGTGATCATGGTG; AATTACATCTTCTTTAAAGCTAAGTGGGAGACAAGCTTCAACCACAAAGGCACCCAAGAG; CAAGACTTCTACGTGACCTCGCAGACTGTGGTGCGGGTACCCATGATGAGCCGCGAGGAT; CAGTATCACTACCTCCTGGACCGGAACCTCTCCTGCAGGGTGGTGGGGGTCCCCTACCAA; GGCAATGCCACGGCTTTGTTCATTCTCCCCAGTGAGGGAAAGATGCAGCAGGTGGAGAAT; GGACTGAGTGAGAAAACGCTGAGGAAGTGGCTTAAGATGTTCAAAAAGAGGCAGCTCGAG; CTTTACCTTCCCAAATTCTCCATTGAGGGCTCCTATCAGCTGGAGAAAGTCCTCCCCAGT; CTGGGGATCAGTAACGTCTTCACCTCCCATGCTGATCTGTCCGGCATCAGCAACCACTCA; AATATCCAGGTGTCTGAGATGGTGCACAAAGCTGTGGTGGAGGTGGACGAGTCGGGAACC; AGAGCAGCGGCAGCCACGGGGACAATATTCACTTTCAGGTCGGCCCGCCTGAACTCTCAG; AGGCTAGTGTTCAACAGGCCCTTTCTGATGTTCATTGTGGATAACAACATCCTCTTCCTT; GGCAAAGTGAACCGCCCCTGA; ; Clone variation with respect to NM_000624.4; 291 c=>a;682 g=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000624 unedited; AATTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTGCCACCTCCA; CTGTGTGCACACTCAGCTACGGGACACATTTCAGGTATCCAAGGCAGCAGAGGTGAGTGG; GTCCCCCGAGCTCTGTGACCTTATGCTCCACACTAACTCTGGCAGAGCCTCCGTTTCCTC; ATAGAACAAAGAACAGCCACCATGCAGCTCTTCCTCCTCTTGTGCCTGGTGCTTCTCAGC; CCTCAGGGGGCCTCCCTTCACCGCCACCACCCCCGGGAGATGAAGAAGAGAGTCGAGGAC; CTCCATGTAGGTGCCACGGTGGCCCCCAGCAGCAGAAGGGACTTTACCTTTGACCTCTAC; AGGGCCTTGGCTTCCGCTGCCCCCAGCCAGAGCATCTTCTTCTCCCCTGTGAGCATCTCC; ATGAGCCTGGCCATGCTCTCCCTGGGGGCTGGGTCCAGCACAAAGATGCAGATCCTGGAG; GGCCTGNGCCTAAACCTCCAGAAAAGCTCAGAGAAGGAGCTGCACAGAGGCTTTCAGCAG; CTCCTTCAGGAACTCAACCAGCCCAGAGATGGCTTCCAGCTGAGCCTCGGCAATGCCCTT; TTCACCGACCTGGTGGTAGACCTGCAGGACACCTTCGTAAGTGCCATGAAGACGCTGTAC; CTGGCAGACACTTTCCCTACCAACTTTAGGGACTCTGCAGGGGCCATGAAGCAGATCAAT; GATTATGTGGCANAGCANACGAAGGGCAAGATTGTGGACTTGCTTAAGAACCTCGATAGC; ATGCGGNCGTGATCATGGNGGATTACATCTTCCTTAAAGCTAAGTGGGAGACAGCTCCAC; CCCAAAGCACCCAGAGCAGACTTCTACGTGACCTCCAGATGTGGTGCCGGTACCCATGAG; G;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000624 unedited; CCCCCCGGCCCACTTCTTCCCCCCCCCCCCCCCTTGGGGGGAAGAAACCTTGTTTATGCC; AACTAGNAATCACAAGTTAGTCATTGGCACCTGCAACTGATACTCTACTATTTGCAAAAG; GCTTCCCTTCTTCCACTCCCAGCCAGGCCCATCAGATTATAACTATATCCACAAAATGAT; ATAATCAATCATTAAATGGGCCATTTCCACCTTGATATCCAGATGTTTTTCTTAAAGGAT; GAATGGCACTTGAGTGTATTGAAATCAACCACGAATGACAGGGCCCACCCCAGCCTTTCT; ATATGATTTCAGGAGTTCTTGGGTCACAGCAAGAATCTGATCCTTGTATACAGAGGGAAA; CTGAGGTCCAGAGAGGGAAAGTGTTGTCCCAATGTCACACAGCACATTAGGACTGAAACA; GTAGCCCCATTTCAGACTCCCATTCCAACATTTTTCCCATGCAGGATGAACTGACAGTTG; TTGCTGCTGATAAGTGTGGGACCAGCCTTGGACCTGTGCTTCCTGGTGGCCCTCATCCAC; TGGAACATCCCTCCTATTGAGCTTTGTGGCACTGAGCTGGGCATCAAGGGCCAGGACTCT; GGACCTCTCTTTGCCACTACCATGCTGGTGAACTTGAGCAAGTCATCCAGCCTCTCTGGA; TCTCAGNGTTAATCTTCATTGATGAATAGTGACCGCAAGATTGAATGTTCTCCACATTTT; CCCCAGGCACCTGTATGTTGCACCCGTGTGGTTGGAAGCAATCATCATAGAGTAATATTA; CTTGCCATGCCTCATTAATTAACTAAACCTGGGTAAATAACTAACTAACAGCATACAGAT; GGCCCATAGCTTAACCCCCTTCATCTCCCAACCTGCAGCCTGTAGATTTAAAGAAAAACT; CACCCTTAGGGGCGGGTCAATTTGGCAAGGCAGAAGATGTTGTTTTCCCACATGCACCAC; CAAAAAGGGCCT;
• Restriction Sites: NotI-NotI
• ACCN: NM_000624
• Insert Size: 2400 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000624.3, NP_000615.2
• RefSeq Size: 2245 bp
• RefSeq ORF: 1221 bp
• Locus ID: 5104
• UniProt ID: P05154
• Cytogenetics: 14q32.13
• Domains: SERPIN
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Complement and coagulation cascades
• Summary: The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. This family member is a glycoprotein that can inhibit several serine proteases, including protein C and various plasminogen activators and kallikreins, and it thus plays diverse roles in hemostasis and thrombosis in multiple organs. [provided by RefSeq, Aug 2012]