CD62L (SELL) (NM_000655) Human Untagged Clone

SKU SC119745

SELL (untagged)-Human selectin L (SELL), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: CD62L
• Synonyms: CD62L; LAM1; LECAM1; LEU8; LNHR; LSEL; LYAM1; PLNHR; TQ1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119745 sequence for NM_000655 edited (data generated by NextGen Sequencing); ATGGGCTGCAGAAGAACTAGAGAAGGACCAAGCAAAGCCATGATATTTCCATGGAAATGT; CAGAGCACCCAGAGGGACTTATGGAACATCTTCAAGTTGTGGGGGTGGACAATGCTCTGT; TGTGATTTCCTGGCACATCATGGAACCGACTGCTGGACTTACCATTATTCTGAAAAACCC; ATGAACTGGCAAAGGGCTAGAAGATTCTGCCGAGACAATTACACAGATTTAGTTGCCATA; CAAAACAAGGCGGAAATTGAGTATCTGGAGAAGACTCTGCCTTTCAGTCGTTCTTACTAC; TGGATAGGAATCCGGAAGATAGGAGGAATATGGACGTGGGTGGGAACCAACAAATCTCTT; ACTGAAGAAGCAGAGAACTGGGGAGATGGTGAGCCCAACAACAAGAAGAACAAGGAGGAC; TGCGTGGAGATCTATATCAAGAGAAACAAAGATGCAGGCAAATGGAACGATGACGCCTGC; CACAAACTAAAGGCAGCCCTCTGTTACACAGCTTCTTGCCAGCCCTGGTCATGCAGTGGC; CATGGAGAATGTGTAGAAATCATCAATAATTACACCTGCAACTGTGATGTGGGGTACTAT; GGGCCCCAGTGTCAGTTTGTGATTCAGTGTGAGCCTTTGGAGGCCCCAGAGCTGGGTACC; ATGGACTGTACTCACCCTTTGGGAAACTTCAGCTTCAGCTCACAGTGTGCCTTCAGCTGC; TCTGAAGGAACAAACTTAACTGGGATTGAAGAAACCACCTGTGGACCATTTGGAAACTGG; TCATCTCCAGAACCAACCTGTCAAGTGATTCAGTGTGAGCCTCTATCAGCACCAGATTTG; GGGATCATGAACTGTAGCCATCCCCTGGCCAGCTTCAGCTTTACCTCTGCATGTACCTTC; ATCTGCTCAGAAGGAACTGAGTTAATTGGGAAGAAGAAAACCATTTGTGAATCATCTGGA; ATCTGGTCAAATCCTAGTCCAATATGTCAAAAATTGGACAAAAGTTTCTCAATGATTAAG; GAGGGTGATTATAACCCCCTCTTCATTCCAGTGGCAGTCATGGTTACTGCATTCTCTGGG; TTGGCATTTATCATTTGGCTGGCAAGGAGATTAAAAAAAGGCAAGAAATCCAAGAGAAGT; ATGAATGACCCATATTAA; ; Clone variation with respect to NM_000655.4;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000655 unedited; NCCCGTTCAGAATTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGCAGCAC; AGCACACTCCCTTTGGGCAAGGACCTGAGACCCTTGTGCTAAGTCAAGAGGCTCAATGGG; CTGCAGAAGAACTAGAGAAGGACCAAGCAAAGCCATGATATTTCCATGGAAATGTCAGAG; CACCCAGAGGGACTTATGGAACATCTTCAAGTTGTGGGGGTGGACAATGCTCTGTTGTGA; TTTCCTGGCACATCATGGAACCGACTGCTGGACTTACCATTATTCTGAAAAACCCATGAA; CTGGCAAAGGGCTAGAAGATTCTGCCGAGACAATTACACAGATTTAGTTGCCATACAAAA; CAAGGCGGAAATTGAGTATCTGGAGAAGACTCTGCCTTTCAGTCGTTCTTACTACTGGAT; AGGAATCCGGAAGATAGGAGGAATATGGACGTGGGTGGGAACCAACAAATCTCTTACTGA; AGAAGCAGAGAACTGGGGAGATGGTGAGCCCAACAACAAGAAGAACAAGGAGGACTGCGT; GGAGATCTATATCAAGAGAAACAAAGATGCAGGCAAATGGAACGATGACGCCTGCCACAA; ACTAAAGGCAGCCCTCTGTTACACAGCTTCTTGCCAGCCCTGGTCATGCAGTGGCCATGG; AGAATGTGTAGAAATCATCAATAATTACACCTGCAACTGTGATGTGGGGTACTATGGGCC; CCAGTGTCAGTTTGTGATTCAGTGTGAGCCTTTGGAGGCCCCAGAGCTGGGTACCATGGA; CTGTACTCACCCTTTNGGGAACTTCAGCTTCAGCTCACAGTGTGCCTTCAGCTGCTCTGA; AGGAACAACTTACTGGGATTGAAGAAACCACTGTGGACATTGGNAACTGGTCATCTNCAG; AACCACTGTCAGTC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000655 unedited; CGCGGCCGCATCTANATCGAGTTTTTTTTTTTTTTTTTTAACACTTAAAAAGCAGGCTTT; ATTCAAATGCAAAATTGCATGTTACAGGGTAACCTTTCAGTAAGAAGCCAGGAAGAGGAG; CTCATCATGGGTTGGATTAGTAAAGGACTAGTTATAAAAGAAGTGGTGGGGTTGAGGGAG; GCCTGAGATGAAATTTAAAGAATATGTAGAATCTAGGTAAGTGGATAAAAGGTCTGGGGG; CAGGGGAAAGGAGAGCATTTCATTGTGAATCAAGGAATTTCTCCACCTGTTTTAACTCTT; CCATATGACATCAAAGAGATGTCACTTGCAGCTAGCATTTCAGTGATGTTTTCTTACTAA; TAATATCGTGATAAAAGAAACATTGACTATAAGAAATAGGAATGGGTCTCATAAAAGGAA; ACAGCAAAACCCCCAAACTAAAAAACAGCGCAGGCTATTTCTCTCTTCTCTCCTTTTGCT; TGGCACTCATGAGATGCTAGGTGTGGAAGTCACCCAACTGAAAAAGAGAGGTGGCTGAAC; AAAGTGGGGAGGCTTAACCCACTTAAATAGGATGGGCCAATTCACAGACGGCGAGGTCTA; CAGCGCAAATACGACCTCTTTACCTTGACCATGACCCCATTTCTTTCCTGGAGTTTAAAA; AAAGGGTACCCGACACTTCTTGACCTTCTATATTAACGTCCCTTCCCAGCTTCCGAAAAC; CTCGTTCATTCGCTTTTTCCCCACACCTCCTCCCCACTCCCATTAGGACCCTATATTTTA; CTTCTCTTATACCACCCCTGCCACCAGTTTCCCCCCTTAGAATTGCCCTCTATACCTTTT; TTATAAATACCCAACATATATTCTTTTATTTAATGTATAATTGTCTACCTCCCCCCGCAC; TTTATTAATCCCTACCATCCCTCCGCCCTGCATTTTTATGTATN;
• Restriction Sites: NotI-NotI
• ACCN: NM_000655
• Insert Size: 2450 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000655.2, NP_000646.1
• RefSeq Size: 2324 bp
• RefSeq ORF: 1119 bp
• Locus ID: 6402
• UniProt ID: P14151
• Cytogenetics: 1q24.2
• Domains: CCP, CLECT, EGF
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)
• Summary: This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]; Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein. CCDS Note: The coding region has been scaled back at the 5' end to begin from a start codon that is better supported by conservation data.