GABA A Receptor alpha 1(GABRA1) (NM_000806) Human Untagged Clone

CAT#: SC119668

GABRA1 (untagged)-Human gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), transcript variant 1

USD 196


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Size
    • 10 ug

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Specifications

Product Data
Product Name GABA A Receptor alpha 1(GABRA1) (NM_000806) Human Untagged Clone
Symbol GABRA1
Synonyms ECA4; EIEE19; EJM; EJM5
Vector pCMV6-XL5
Sequence Data
Fully Sequenced ORF
>OriGene ORF within SC119668 sequence for NM_000806 edited (data generated by NextGen Sequencing)
ATGAGGAAAAGTCCAGGTCTGTCTGACTGTCTTTGGGCCTGGATCCTCCTTCTGAGCACA
CTGACTGGAAGAAGCTATGGACAGCCGTCATTACAAGATGAACTTAAAGACAATACCACT
GTCTTCACCAGGATTTTGGACAGACTCCTAGATGGTTATGACAATCGCCTGAGACCAGGA
TTGGGAGAGCGTGTAACCGAAGTGAAGACTGATATCTTCGTCACCAGTTTCGGACCCGTT
TCAGACCATGATATGGAATATACAATAGATGTATTTTTCCGTCAAAGCTGGAAGGATGAA
AGGTTAAAATTTAAAGGACCTATGACAGTCCTCCGGTTAAATAACCTAATGGCAAGTAAA
ATCTGGACTCCGGACACATTTTTCCACAATGGAAAGAAGTCAGTGGCCCACAACATGACC
ATGCCCAACAAACTCCTGCGGATCACAGAGGATGGCACCTTGCTGTACACCATGAGGCTG
ACAGTGAGAGCTGAATGTCCGATGCATTTGGAGGACTTCCCTATGGATGCCCATGCTTGC
CCACTAAAATTTGGAAGTTATGCTTATACAAGAGCAGAAGTTGTTTATGAATGGACCAGA
GAGCCAGCACGCTCAGTGGTTGTAGCAGAAGATGGATCACGTCTAAACCAGTATGACCTT
CTTGGACAAACAGTAGACTCTGGAATTGTCCAGTCAAGTACAGGAGAATATGTTGTTATG
ACCACTCATTTCCACTTGAAGAGAAAGATTGGCTACTTTGTTATTCAAACATACCTGCCA
TGCATAATGACAGTGATTCTCTCACAAGTCTCCTTCTGGCTCAACAGAGAGTCTGTACCA
GCAAGAACTGTCTTTGGAGTAACAACTGTGCTCACCATGACAACATTGAGCATCAGTGCC
AGAAACTCCCTCCCTAAGGTGGCTTATGCAACAGCTATGGATTGGTTTATTGCCGTGTGC
TATGCCTTTGTGTTCTCAGCTCTGATTGAGTTTGCCACAGTAAACTATTTCACTAAGAGA
GGTTATGCATGGGATGGCAAAAGTGTGGTTCCAGAAAAGCCAAAGAAAGTAAAGGATCCT
CTTATTAAGAAAAACAACACTTACGCTCCAACAGCAACCAGCTACACCCCTAATTTGGCC
AGGGGCGACCCGGGCTTAGCCACCATTGCTAAAAGTGCAACCATAGAACCTAAAGAGGTC
AAGCCCGAAACAAAACCACCAGAACCCAAGAAAACCTTTAACAGTGTCAGCAAAATTGAC
CGACTGTCAAGAATAGCCTTCCCGCTGCTATTTGGAATCTTTAACTTAGTCTACTGGGCT
ACGTATTTAAACAGAGAGCCTCAGCTAAAAGCCCCCACACCACATCAATAG

Clone variation with respect to NM_000806.5
5' Read Nucleotide Sequence
>OriGene 5' read for NM_000806 unedited
TGTAAACGCTCCTCAGGGCGGCCGCGACTTCGGCACGAGGCTGACTTCTAAAAATCCTCC
TCTCCCTCTCCCTTTTCCTAATCCGAGAATGATGGAGCTCGAGGCAAAGGAATGATTCCG
GAAATGGAGATATGATTCTCAAACCTAGAAAATGATCGGAGTGATTTATTAGTTAAATAT
TCTTCGTCCAGGAACCCAGCACAATTCAGAGCTGCAGATTGGATATTGGGAAGCAAATTT
GGGTGTGAAATCTTCAGCAAAGGAGCACGCAGAGTCCATGATGGCTCAGACCAAGTGAGT
GAGAGGCAGAGCGAGGACGCCCCTCTGCTCTGGCGCGCCCGGACTCGGACTCGCAGACTC
GTGCTGGCTCCAGTCTCTCCACGATTCTCTCTCCCAGACTTTTCCCCGGTCTTAAGAGAT
CCTGTGTCCAGAGGGGGCCTTAGCTGCTCCAGCCCGCGATGAGGAAAAGTCCAGGTCTGT
CTGACTGTCTTTGGGCCTGGATCCTCCTTCTGAGCACACTGACTGGAAGAAGCTATGGAC
AGCCGTCATTACAAGATGAACTTAAAGACAATACCACTGTCTTCACCAGGATTTTGGACA
GACTCCTAGATGGTTATGACAATCGCCTGAGACCAGGATTGGGAAGAGCGTGTAACCGAA
GTGAAGACTGATATTCTTCGTCACCAGTTTCGGGACCCGTTTTCAGACCATGATATGGGA
TATACAATAGATGTATTTTTTTCCGTCAAGCTGGAAGGATGGAAGGTNTAAAATTAAAGG
GACTTATGAACGGTCCCTCCGGTAAAATAACCTATGGGCAAGAAAATCTGGGACTTCGAC
ACATTTTTTTCCATGGAAAGAAATAATGGGCCACAACATGACCATGCCCAAAAATCCTGG
GGATAAAAGAAAAGGACCTTTTGTGACACATGAAGGGGAGAGAAAAAGA
3' Read Nucleotide Sequence
>OriGene 3' read for NM_000806 unedited
GGCAACCTTCCAGGGCCAGGNANAGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGAT
CTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTT
TTTCTTGGATCTTTGAACCATCTTCCCCCTCTTTTCTCTCTCATTCTGTCTCCTTCTGAC
ATGACTTTGCTCTTTCGCTTGCTCTGTCAAAATCCTGTCTCCAAGCTGCATAGTCTGCTT
TGCTCCAAACTGCCAGACAGGGGTCTCTTGTTCTTAAATGAATTATGAAAATAAGGAAAC
TTTCAAATTCTTTAAGACAGAGGCAATAAAGCAGATGGGAATTACTGCGTTGAGAACATA
AATAAATTCCCAGTGCAGAGGACTGAACAACAGAATGTGAGTAAAAGATCTATCGCCCNN
CCGNGGGGGCTTTTAGCTGAGGCTCTCTGTTTAAATACGTAGCCCAGTAGACTAAGTTAA
AGATTCCAAATAGCAGCGGGAAGGCTATTCTTGACAGTCGGTCAATTTTGCTGACACTGT
TAAAGGTTTTCTTGGGTTCTGGTGGTTTTGTTTCGGGCTTGACCTCTTTAGGTTCTATGG
TTGCACTTTTAACAATGGTGGCTAAGCCCGGGTCGCCCCTGGCCAAATANGGGTGTANCT
GGTTGCTGTTGGAGCGTAAGAGTTGTTTTTCTTATAAGAGGATCCTTTACTTTCTTTGCG
CTTTCTGCAGCCCCNNAATCGCCACTCCATGCCATACCTCTCTTAATGAAATAGTTTACT
GTGGCAAACTCAATCAGAGCTGAGAACACAAAGGCTTAGCACACGGCAATANACCATCCC
TTAACTGGTGCCATAACCACCTTAGGGAGGGGGNTTCCTGGCACTGATGCTCAATGTTGT
CATGGTGGAGCCCAGTTGTTCTCCAAAAACAGTCTTTGCTGGTAC
Restriction Sites NotI-NotI     
Tag Tag Free
ACCN NM_000806
ORF Size 1371 bp
Insert Size 2290
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq NM_000806.3, NP_000797
RefSeq Size 3678
RefSeq ORF 1371
Locus ID 2554
Cytogenetics 5q34
Domains Neur_chan_memb, Neur_chan_LBD
Protein Families Ion Channels: Cys-loop Receptors, Transmembrane, Druggable Genome
Protein Pathways Neuroactive ligand-receptor interaction
Gene Summary This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].
Transcript Variant: This variant (1) uses the 5'-most alternate exon in the 5' UTR. Variants 1-7 encode the same protein.
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Citations