FOLR2 (NM_000803) Human Untagged Clone

CAT#: SC119666

FOLR2 (untagged)-Human folate receptor 2 (fetal) (FOLR2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FOLR2
• Synonyms: BETA-HFR; FBP; FBP/PL-1; FOLR1; FR-BETA; FR-P3; FRbeta
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119666 sequence for NM_000803 edited (data generated by NextGen Sequencing)
  ATGGTCTGGAAATGGATGCCACTTCTGCTGCTTCTGGTCTGTGTAGCCACCATGTGCAGT
  GCCCAGGACAGGACTGATCTCCTCAATGTCTGTATGGATGCCAAGCACCACAAGACAAAG
  CCAGGTCCTGAGGACAAGCTGCATGACCAATGCAGTCCCTGGAAGAAGAATGCCTGCTGC
  ACAGCCAGCACCAGCCAGGAGCTGCACAAGGACACCTCCCGCCTGTACAACTTTAACTGG
  GACCACTGCGGCAAGATGGAGCCCGCCTGCAAGCGCCACTTCATCCAGGACACCTGTCTC
  TATGAGTGCTCACCCAACCTGGGGCCCTGGATCCAGCAGGTGAATCAGAGCTGGCGCAAA
  GAACGCTTCCTGGATGTGCCCTTATGCAAAGAGGACTGTCAGCGCTGGTGGGAGGATTGT
  CACACCTCCCACACGTGCAAGAGCAACTGGCACAGAGGATGGGACTGGACCTCAGGAGTT
  AACAAGTGCCCAGCTGGGGCTCTCTGCCGCACCTTTGAGTCCTACTTCCCCACTCCAGCT
  GCCCTTTGTGAAGGCCTCTGGAGTCACTCATACAAGGTCAGCAACTACAGCCGAGGGAGC
  GGCCGCTGCATCCAGATGTGGTTTGATTCAGCCCAGGGCAACCCCAACGAGGAAGTGGCG
  AGGTTCTATGCTGCAGCCATGCATGTGAATGCTGGTGAGATGCTTCATGGGACTGGGGGT
  CTCCTGCTCAGTCTGGCCCTGATGCTGCAACTCTGGCTCCTTGGCTGA
  
  Clone variation with respect to NM_000803.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000803 unedited
  TTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGGTCTACCCTGTACCGAA
  GACAGAGGCTGTGGGGACAGCCTAGGGGCCTGGATCTATTGCCTACTTAGAGAGAGGCCA
  ACTCAGACACAGCCGTGTATGCTCCCAGCAGCAACGGAGGTTCAGCTCCGCCTGCAGGGA
  CAGAAAGACATGGTCTGGAAATGGATGCCACTTCTGCTGCTTCTGGTCTGTGTAGCCACC
  ATGTGCAGTGCCCAGGACAGGACTGATCTCCTCAATGTCTGTATGGATGCCAAGCACCAC
  AAGACAAAGCCAGGTCCTGAGGACAAGCTGCATGACCAATGCAGTCCCTGGAAGAAGAAT
  GCCTGCTGCACAGCCAGCACCAGCCAGGAGCTGCACAAGGACACCTCCCGCCTGTACAAC
  TTTAACTGGGACCACTGCGGCAAGATGGAGCCCGCCTGCAAGCGCCACTTCATCCAGGAC
  ACCTGTCTCTATGAGTGCTCACCCAACCTGNGGCCCTGGATCCAGCAGGTGAATCAGAGC
  TGGCGCAAAGAACGCTTCCTGGATGTGCCCTTATGCAAAGAGGACTGTCAGCGCTGGTGG
  GAGGATTGTCACACCTCCCACACGTGCAAGAGCAACTGGCACAGAGGATGGGACTGGACC
  TCANGAGTTAACAAGTGCCCAGCTGGGGCTCTCTGCCGCACCTTTGAGTCCTACTTCCCC
  ACTNCAGCTGCCCTTTGTGAAGGCCTNCTGGAGTCACTCATACANGGGTCAGCACTACAG
  CCGAGGGAGCGGCCGCTGCATCCAGATTGTGGTTTGATTCAGCCAGGGCAACCCACGAGG
  AAGGGGCGAGTTCTTGCTGCAGCATGCATGGATGCTGNGAGAGCTCATGGACCTGGGGTC
  TCTGCTCATCTGGCCTGAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000803 unedited
  ATGAACCGCGGCACGCAATCTATAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCTTTTTATAAAAAAACAATCTGTTTATTA
  AAAAGGACTTTTGGCCCCCCCATGGAACAACAACAAACTGGGGGACAAAGGGTTAGGGGA
  CTAAAAAAACCATGCTTAAGGGGCTGTCTTTTGGGGGAACTGAACTGACCCCACCCTGGT
  TATCCAAACTGAGGGCAGGTATTCTGGGAGGACTGAACTCACCCAAGGAGCCAAATTTGC
  ACCATCAGGGCCAAACTGAACAGGAAACCCCCAGTCCCATGAAACATTTCACCAACATTC
  ACATGCATGGGTGGAGAAAAAAACCCCCCCACTTCCTCGTTGGGGTTGCCCTGGGCTGAA
  TCAAACCACATTTGGATGCAGGGGCCGCTCCCTCGGGTGTAATTGCTGACCTTGTATAAA
  GGACCCCAAAGGCCTTCCCAAAGGGCATCTGGAGGGGGGAATTAGGACTCAAAGGGGCGG
  CAAAAAGCCCCAGCTGGGCCCTTGTTAACTCCTGAGGCCCAATCCCATCCTTTGTGCCAA
  TTGCTCTTGCACGTGGGGGAAGTGTGACAATCCTCCCACCAACGCTAGAAGTTCCTTTTG
  CATAAGGGCACATCCAGGAAAGCGTTCTTTGCGCCACTTCTGATTCACCTGCTGGATACA
  CAGCCCCAGGGTGGGGTGAGCCCTCTTAAAAAAAGGGTCCTGGAATAAATGGCCCTTGGA
  AGCCGGCTCCTTTTGCCCGAGGGGCCCAAGTTAAGTTGTCAGGCGGGAGGGGGCCCTTGG
  CACCCTCTGGTGGGGGCGGGGTGGCCAAAAGCATTTTTTTCCAGGGACTGGTTTGGCATG
  CAACTTGTTCTCAGACCCGTCTTTTTTTTGGGGGGCTGCGCCCCATAAAACCTGGGGGAA
  AAAACCCCGCCTCGGCCTGGCAAGGGGGCTCAAAAAACAAAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000803
• Insert Size: 1240 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000803.2, NP_000794.1
• RefSeq Size: 1119 bp
• RefSeq ORF: 768 bp
• Locus ID: 2350
• UniProt ID: P14207
• Cytogenetics: 11q13.4
• Domains: Folate_rec
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longest transcript. All variants (1-4) encode the same protein.