Calcitonin receptor (CALCR) (NM_001742) Human Untagged Clone

SKU SC119074

CALCR (untagged)-Human calcitonin receptor (CALCR), transcript variant 2

Product Data

• Type: Human Untagged Clone
• Target Symbol: Calcitonin receptor
• Synonyms: CRT; CT-R; CTR; CTR1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119074 sequence for NM_001742 edited (data generated by NextGen Sequencing); ATGAGGTTCACATTTACAAGCCGGTGCTTGGCACTGTTTCTTCTTCTAAATCACCCAACC; CCAATTCTTCCTGCCTTTTCAAATCAAACCTATCCAACAATAGAGCCCAAGCCATTTCTT; TACGTCGTAGGACGAAAGAAGATGATGGATGCACAGTACAAATGCTATGACCGAATGCAG; CAGTTACCCGCATACCAAGGAGAAGGTCCATATTGCAATCGCACCTGGGATGGATGGCTG; TGCTGGGATGACACACCGGCTGGAGTATTGTCCTATCAGTTCTGCCCAGATTATTTTCCG; GATTTTGATCCATCAGAAAAGGTTACAAAATACTGTGATGAAAAAGGTGTTTGGTTTAAA; CATCCTGAAAACAATCGAACCTGGTCCAACTATACTATGTGCAATGCTTTCACTCCTGAG; AAACTGAAGAATGCATATGTTCTGTACTATTTGGCTATTGTGGGTCATTCTTTGTCAATT; TTCACCCTAGTGATTTCCCTGGGGATTTTCGTGTTTTTCAGGAGCCTTGGCTGCCAAAGG; GTAACCCTGCACAAGAACATGTTTCTTACTTACATTCTGAATTCTATGATTATCATCATC; CACCTGGTTGAAGTAGTACCCAATGGAGAGCTCGTGCGAAGGGACCCGGTGAGCTGCAAG; ATTTTGCATTTTTTCCACCAGTACATGATGGCCTGCAACTATTTCTGGATGCTCTGTGAA; GGGATCTATCTTCATACACTCATTGTCGTGGCTGTGTTTACTGAGAAGCAACGCTTGCGG; TGGTATTATCTCTTGGGCTGGGGGTTCCCGCTGGTGCCAACCACTATCCATGCTATTACC; AGGGCCGTGTACTTCAATGACAACTGCTGGCTGAGTGTGGAAACCCATTTGCTTTACATA; ATCCATGGACCTGTCATGGCGGCACTTGTGGTCAATTTCTTCTTTTTGCTCAACATTGTC; CGGGTGCTTGTGACCAAAATGAGGGAAACCCATGAGGCGGAATCCCACATGTACCTGAAG; GCTGTGAAGGCCACCATGATCCTTGTGCCCCTGCTGGGAATCCAGTTTGTCGTCTTTCCC; TGGAGACCTTCCAACAAGATGCTTGGGAAGATATATGATTACGTGATGCACTCTCTGATT; CATTTCCAGGGCTTCTTTGTTGCGACCATCTACTGCTTCTGCAACAATGAGGTCCAAACC; ACCGTGAAGCGCCAATGGGCCCAATTCAAAATTCAGTGGAACCAGCGTTGGGGGAGGCGC; CCCTCCAACCGCTCTGCTCGCGCTGCAGCCGCTGCTGCGGAGGCTGGCGACATCCCAATT; TACATCTGCCATCAGGAGCCGAGGAATGAACCAGCCAACAACCAAGGCGAGGAGAGTGCT; GAGATCATCCCTTTGAATATCATAGAGCAAGAGTCATCTGCTTGA; ; Clone variation with respect to NM_001742.3; 1340 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001742 unedited; CCCATTTTGTAATACGACTTCACTATAGGGCGGCCGCGATTCGGCACGAGGGGCTGCGCC; GCGCGGCTGGCGGACCTTCCCGGGTTGGAGAAGTGCGCACGTCCGCACCTCACCCTGCGG; CTGACATCTCCTGCCCAGGAGATGGGCGCTGAAGCTTGAGCGCCTGAGTCCCTGGAGCCA; CACCTGCGAACACCCTTTGCTTCTATTGAGCTGTGCCCAGCCGCCCAGTGACAGAATTCC; AGGACAAAGAGATCTTCAAAAACCAAAAATGAGGTTCACATTTACAAGCCGGTGCTTGGC; ACTGTTTCTTCTTCTAAATCACCCAACCCCAATTCTTCCTGCCTTTTCAAATCAAACCTA; TCCAACAATAGAGCCCAAGCCATTTCTTTACGTCGTAGGACGAAAGAAGATGATGGATGC; ACAGTACAAATGCTATGACCGAATGCAGCAGTTACCCGCATACCAAGGAGAAGGTCCATA; TTGCAATCGCACCTGGGATGGATGGCTGTGCTGGGATGACACACCGGCTGGAGTATTGTC; CTATCAGTTCTGCCCAGATTATTTTCCGGATTTTGATCCATCAGANAAGGTTACAAAATA; CTGTGATGAAAAAGGTGTTTGGTTTAAACATCCTGAANACAATCGAACCTGGTCCAACTA; TACTATGTGCAAATGCTTCACTCCTGAGGAACTGAAGAATGCATATGTTCTGTACTATTT; GGCTATTGTGGGTCATTCTTTGTCATTTTTCACCCTAGTGATTTTCCTGGGGATTTTCGT; GTTTTTCAGGAGCCTGGGCTGCCANNAGGTAACCCTGCACAAGAACATGGTTTCTACTTA; CATTCTGAAATCCTATGATATCATCATCCACCTGTTTGAAGTAATACCAATGGAAAGCTC; GTGCCAAGGGACCCCGTGAGCTGCAGGATTTGCATTTTTTCACCAGTCCAGGAT;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001742 unedited; CGGGGGAATATGAGTNCTCTGTCTTATTTTAACATATACACAAACATAAGCATTTCACAT; AATTTGGGCAGAACTATGTGCAATTCTATAATAAGCTATTTTGTTTTCTTCAACCCCTAC; TATATTAGCATAATAACATCTAAAATATTTTAGCAATATATTATCACATTTGTACCACAG; CTGCCAGAAATACTCTGTTTTCCATGTTTGTAAACAAAAATAGAACAATACTACATAACA; CTGTGATTGGAAAAATACCTTCTTTTCGATCCCCCCCTTACATTCAGTAAAGGAGACTTA; AACTACTTTAGTATCCCAAATTCATTTTCTCTGTAGAAATATAATTAATTTTCTCTGGGT; GCGCTAAATATGTAACCATAACAAATCAATTTATTATCTTTCCACAACTAAATCACTTCT; GAAAGGCAGTGGCAAAATATGACATAGATGAGACTGGAGATTTGGAGGGTTTCAATGTAC; CTCCTCATTTAGCATACAAATTAAATAATGGTAACTCTGATTACTGTTGCAAATTCACAA; ATTAATTTCAGGTGCCAGTAACGATACTGGTTTATTCAGGATTTTCAGAAATCTTATACT; GGGAAGTAAAGAGAGATATGATAATATAATACTGGATTTTAATGAGAAACGTTAAACCTG; AATTGAGTTATGGTTAAATTTGGAGCAGTTAATTTTTTGCCCTCCTGTTTTGGTAATAAC; CAAAACAAAGCGGTCAACGACAGTTTGATTTCCAATTAGGCCCTCCTGGATATTCCGGGG; AAAGCCGTGAACTTTTTTAAGCCTTGAAGCTGGGGGGAAAGCATTAAGGGACTTTGGGGG; GGCTTTTAATAGCAGGAGGAAGGATGTAACCTTACGGGTAGAAGCGCC;
• Restriction Sites: Please inquire
• ACCN: NM_001742
• Insert Size: 3900 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001742.2, NP_001733.1
• RefSeq Size: 3470 bp
• RefSeq ORF: 1425 bp
• Locus ID: 799
• UniProt ID: P30988
• Cytogenetics: 7q21.3
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Summary: This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]; Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Variants 2 and 3 encode the same isoform (2). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.