N Cadherin (CDH2) (NM_001792) Human Untagged Clone

CAT#: SC119018

CDH2 (untagged)-Human cadherin 2, type 1, N-cadherin (neuronal) (CDH2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: N Cadherin
• Synonyms: ACOGS; ARVD14; CD325; CDHN; CDw325; NCAD
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001792 edited
  GAATTCGGCACGAGGGCTGCCGCTGCCTCCTCCTCCTCCGCCGCCGCCGCCGCCGCCGCC
  GCCTCCTCCGGCTCTTCGCTCGGCCCCTCTCCGCCTCCATGTGCCGGATAGCGGGAGCGC
  TGCGGACCCTGCTGCCGCTGCTGGCGGCCCTGCTTCAGGCGTCTGTAGAGGCTTCTGGTG
  AAATCGCATTATGCAAGACTGGATTTCCTGAAGATGTTTACAGTGCAGTCTTATCGAAGG
  ATGTGCATGAAGGACAGCCTCTTCTCAATGTGAAGTTTAGCAACTGCAATGGAAAAAGAA
  AAGTACAATATGAGAGCAGTGAGCCTGCAGATTTTAAGGTGGATGAAGATGGCATGGTGT
  ATGCCGTGAGAAGCTTTCCACTCTCTTCTGAGCATGCCAAGTTCCTGATATATGCCCAAG
  ACAAAGAGACCCAGGAAAAGTGGCAAGTGGCAGTAAAATTGAGCCTGAAGCCAACCTTAA
  CTGAGGAGTCAGTGAAGGAGTCAGCAGAAGTTGAAGAAATAGTGTTCCCAAGACAATTCA
  GTAAGCACAGTGGCCACCTACAAAGGCAGAAGAGAGACTGGGTCATCCCTCCAATCAACT
  TGCCAGAAAACTCCAGGGGACCTTTTCCTCAAGAGCTTGTCAGGATCAGGTCTGATAGAG
  ATAAAAACCTTTCACTGCGGTACAGTGTAACTGGGCCAGGAGCTGACCAGCCTCCAACTG
  GTATCTTCATTATCAACCCCATCTCGGGTCAGCTGTCGGTGACAAAGCCCCTGGATCGCG
  AGCAGATAGCCCGGTTTCATTTGAGGGCACATGCAGTAGATATTAATGGAAATCAAGTGG
  AGAACCCCATTGACATTGTCATCAATGTTATTGACATGAATGACAACAGACCTGAGTTCT
  TACACCAGGTTTGGAATGGGACAGTTCCTGAGGGATCAAAGCCTGGAACATATGTGATGA
  CCGTAACAGCAATTGATGCTGACGATCCCAATGCCCTCAATGGGATGTTGAGGTACAGAA
  TCGTGTCTCAGGCTCCAAGCACCCCTTCACCCAACATGTTTACAATCAACAATGAGACTG
  GTGACATCATCACAGTGGCAGCTGGACTTGATCGAGAAAAAGTGCAACAGTATACGTTAA
  TAATTCAAGCTACAGACATGGAAGGCAATCCCACATATGGCCTTTCAAACACAGCCACGG
  CCGTCATCACAGTGACAGATGTCAATGACAATCCTCCAGAGTTTACTGCCATGACGTTTT
  ATGGTGAAGTTCCTGAGAACAGGGTAGACATCATAGTAGCTAATCTAACTGTGACCGATA
  AGGATCAACCCCATACACCAGCCTGGAACGCAGTGTACAGAATCAGTGGCGGAGATCCTA
  CTGGACGGTTCGCCATCCAGACCGACCCAAACAGCAACGACGGGTTAGTCACCGTGGTCA
  AACCAATCGACTTTGAAACAAATAGGATGTTTGTCCTTACTGTTGCTGCAGAAAATCAAG
  TGCCATTAGCCAAGGGAATTCAGCACCCGCCTCAGTCAACTGCAACCGTGTCTGTTACAG
  TTATTGACGTAAATGAAAACCCTTATTTTGCCCCCAATCCTAAGATCATTCGCCAAGAAG
  AAGGGCTTCATGCCGGTACCATGTTGACAACATTCACTGCTCAGGACCCAGATCGATATA
  TGCAGCAAAATATTAGATACACTAAATTATCTGATCCTGCCAATTGGCTAAAAATAGATC
  CTGTGAATGGACAAATAACTACAATTGCTGTTTTGGACCGAGAATCACCAAATGTGAAAA
  ACAATATATATAATGCTACTTTCCTTGCTTCTGACAATGGAATTCCTCCTATGAGTGGAA
  CAGGAACGCTGCAGATCTATTTACTTGATATTAATGACAATGCCCCTCAAGTGTTACCTC
  AAGAGGCAGAGACTTGCGAAACTCCAGACCCCAATTCAATTAATATTACAGCACTTGATT
  ATGACATTGATCCAAATGCTGGACCATTTGCTTTTGATCTTCCTTTATCTCCAGTGACTA
  TTAAGAGAAATTGGACCATCACTCGGCTTAATGGTGATTTTGCTCAGCTTAATTTAAAGA
  TAAAATTTCTTGAAGCTGGTATCTATGAAGTTCCCATCATAATCACAGATTCGGGTAATC
  CTCCCAAATCAAATATTTCCATCCTGCGCGTGAAGGTTTGCCAGTGTGACTCCAACGGGG
  ACTGCACAGATGTGGACAGGATTGTGGGTGCGGGGCTTGGCACCGGTGCCATCATTGCCA
  TCCTGCTCTGCATCATCATCCTGCTTATCCTTGTGCTGATGTTTGTGGTATGGATGAAAC
  GCCGGGATAAAGAACGCCAGGCCAAACAACTTTTAATTGATCCAGAAGATGATGTAAGAG
  ATAATATTTTAAAATATGATGAAGAAGGTGGAGGAGAAGAAGACCAGGACTATGACTTGA
  GCCAGCTGCAGCAGCCTGACACTGTGGAGCCTGATGCCATCAAGCCTGTGGGAATCCGAC
  GAATGGATGAAAGACCCATCCACGCCGAGCCCCAGTATCCGGTCCGATCTGCAGCCCCAC
  ACCCTGGAGACATTGGGGACTTCATTAATGAGGGCCTTAAAGCGGCTGACAATGACCCCA
  CAGCTCCACCATATGACTCCCTGTTAGTGTTTGACTATGAAGGCAGTGGCTCCACTGCTG
  GGTCCTTGAGCTCCCTTAATTCCTCAAGTAGTGGTGGTGAGCAGGACTATGATTACCTGA
  ACGACTGGGGGCCACGGTTCAAGAAACTTGCTGACATGTATGGTGGAGGTGATGACTGAA
  CTTCAGGGTGAACTTGGTTTTTGGACAAGTACAAACAATTTCAACTGATATTCCCAAAAA
  GCATTCAGAAGCTAGGCTTTAACTTTGTAGTCTACTAGCACAGTGCTTGCTGGAGGCTTT
  GGCATAGGCTGCAAACCAATTTGGGCTCAGAGGGAATATCAGTGATCCATACTGTTTGGA
  AAAACACTGAGCTCAGTTACACTTGAATTTTACAGTACAGAAGCACTGGGATTTTATGTG
  CCTTTTTGTACCTTTTTCAGATTGGAATTAGTTTTCTGTTTAAGGCTTTAATGGTACTGA
  TTTCTGAAACGATAAGTAAAAGACAAAATATTTTGTGGTGGGAGCAGTAAGTTAAACCAT
  GATATGCTTCAACACGCTTTTGTTACATTGCATTTGCTTTTATTAAAATACAAAATTAAA
  CAAACAAAAAAACTCATGGAGCGATTTTATTATCTTGGGGGATGAGACCATGAGATTGGA
  AAATGTACATTACTTCTAGTTTTAGACTTTAGTTTGTTTTTTTTTTTTCACTAAAATCTT
  AAAACTTACTCAGCTGGTTGCAAATAAAGGGAGTTTTCATATCACCAATTTGTAGCAAAA
  TTGAATTTTTTCATAAACTAGAATGTTAGACACATTTTGGTCTTAATCCATGTACACTTT
  TTTATTTCTGTATTTTTCCACTTCACTGTAAAAATAGTATGTGTACATAATGTTTTATTG
  GCATAGTCTATGGAGAAGTGCAGAAACTTCAGAACATGTGTATGTATTATTTGGACTATG
  GATTCAGGTTTTTTGCATGTTTATATCTTTCGTTATGGATAAAGTATTTACAAAACAGTG
  ACATTTGATTCAATTGTTGAGCTGTAGTTAGAATACTCAATTTTTAATTTTTTTAATTTT
  TTTATTTTTTATTTTCTTTTTGGTTTGGGGAGGGAGAAAAGTTCTTAGCACAAATGTTTT
  ACATAATTTGTACCAAAAAAAAAAAAAAGGAAAGGAAAGAAAGGGGTGGCCTGACACTGG
  TGGCACTACTAAGTGTGTGTTTTTTTAAAAAAAAAATGGAAAAAAAAAGCTTTTAAACTG
  GAGAGACTTCTGACAACAGCTTTGCCTCTGTATTGTGTACCAGAATATAAATGATACACC
  TCTGACCCCAGCGTTCTGAATAAAATGCTAATTTTGGAAAAAAAAAAAAAAAAAACTCGA
  C
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001792 unedited
  TCCCCCGCCCCGTTGNCGCAAAGGGCGGTAGGCGTGTACGGTGGNGAGTCTATATAAGCA
  GAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGA
  ATTCGGCACGAGGGCTGCCGCTGCCTCCTCCTCCTCCGCCGCCGCCGCCGCCGCCGCCGC
  CTCCTCCGGCTCTTCGCTCGGCCCCTCTCCGCCTCCATGTGCCGGATAGCGGGAGCGCTG
  CGGACCCTGCTGCCGCTGCTGGCGGCCCTGCTTCAGGCGTCTGTAGAGGCTTCTGGTGAA
  ATCGCATTATGCAAGACTGGATTTCCTGAAGATGTTTACAGTGCAGTCTTATCGAAGGAT
  GTGCATGAAGGACAGCCTCTTCTCAATGTGAAGTTTAGCAACTGCAATGGAAAAAGAAAA
  GTACAATATGAGAGCAGTGAGCCTGCAGATTTTAAGGTGGATGAAGATGGCATGGTGTAT
  GCCGTGAGAAGCTTTCCACTCTCTTCTGAGCATGCCAAGTTCCTGATATATGCCCAAGAC
  AAAGAGACCCAGGAAAAGTGGCAAGTGGCAGTAAAATTGAGCCTGAAGCCAACCTTAACT
  GAGGAGTCAGTGAAGGAGTCAGCAGAAGTTGAAGAAATAGTGTTCCCAAGACAATTCAGT
  AAGCACAGTGGCCACCTACAAAGGCAGAAGAGAGACTGGGTCATCCCTCCAATCAACTTG
  CCAGAAAACTCCAGGGGACCTTTTCCTCAAGAGCTTGTCAGGATCAGGTCTGATAGAGAT
  AAAAACCTTTCACTGCGGTACAGTGTAACTGGGCCCAGAGCTGACCAGCCTCCAACTGGG
  TATCTCATTATCAACCCCATCTCGGGTCAGCTGTNCGTGACAAACCCCTGGTCGCGAGCA
  GAAGCCCGGTTTNCATTGANGCACATGCAGTAGATATTAATGGAAATCAGTGGAGAACCC
  CATGNACTTGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001792 unedited
  GGGGGAGACTACNGGGTACCGTGGCCCGCATCNGGGGTACGAGTTTATTTCTTTTTTTTT
  GTCCAAAATTAGCATTTTATTCAGAACGCTGGGGTCAGCGGTGTATCATTTATATTCTGG
  TACACAATACAGAGGCAAAGCTGTTGTCAGAAGTCTCTCCAGTTTAAAAGCTTTTTTTTT
  CCATTTTTTTTTTAAAAAAACACACACTTAGTAGTGCCACCAGTGTCAGGCCACCCCTTT
  CTTTCCTTTCCTTTTTTTTTTTTTTGGTACAAATTATGTAAAACATTTGTGCTAAGAACT
  TTTCTCCCTCCCCAAACCAAAAAGAAAATAAAAAATAAAAAAATTAAAAAAATTAAAAAT
  TGAGTATTCTAACTACAGCTCAACAATTGAATCAAATGTCACTGTTTTGTAAATACTTTA
  TCCATAACGAAAGATATAAACATGCAAAAAACCTGAATCCATAGTCCAAATAATACATAC
  ACATGTTCTGAAGTTTCTGCACTTCTCCATAGACTATGCCAATAAAACATTATGTACACA
  TACTATTTTTACAGTGAAGTGGAAAAATACAGAAATAAAAAAGTGTACATGGATTAAGAC
  CAAAATGTGTCTAACATTCTAGTTTATGAAAAAATTCAATTTTGCTACAAATTGGTGATA
  TGAAAACTCCCTTTATTTGCAACCAGCTGAGTAAGTTTTAAGATTTTAGTGAAAAAAAAA
  AAACAACTTAAGTCTAAAACTAGAAGTAATGTACATTTTTCAATCTCATGGTCTCATCCC
  CCAAGAAATAAAATCGCTCCATGAGTTTTTTGGTTTGGTAAATTTTGGATTTTAAAAAAA
  GCAAATGCCATGTTACAAAAGCGTGTTGAAGCCTTTCATGGTTTAACTTACTGTTCCCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001792
• Insert Size: 4500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001792.2, NP_001783.2
• RefSeq Size: 4122 bp
• RefSeq ORF: 2721 bp
• Locus ID: 1000
• UniProt ID: P19022
• Cytogenetics: 18q12.1
• Domains: Cadherin_C_term, CA
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs)
• Gene Summary: This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).