N Cadherin (CDH2) (NM_001792) Human Untagged Clone

SKU SC119018

CDH2 (untagged)-Human cadherin 2, type 1, N-cadherin (neuronal) (CDH2)

Product Data

• Type: Human Untagged Clone
• Target Symbol: N Cadherin
• Synonyms: ACOGS; ARVD14; CD325; CDHN; CDw325; NCAD
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001792 edited; GAATTCGGCACGAGGGCTGCCGCTGCCTCCTCCTCCTCCGCCGCCGCCGCCGCCGCCGCC; GCCTCCTCCGGCTCTTCGCTCGGCCCCTCTCCGCCTCCATGTGCCGGATAGCGGGAGCGC; TGCGGACCCTGCTGCCGCTGCTGGCGGCCCTGCTTCAGGCGTCTGTAGAGGCTTCTGGTG; AAATCGCATTATGCAAGACTGGATTTCCTGAAGATGTTTACAGTGCAGTCTTATCGAAGG; ATGTGCATGAAGGACAGCCTCTTCTCAATGTGAAGTTTAGCAACTGCAATGGAAAAAGAA; AAGTACAATATGAGAGCAGTGAGCCTGCAGATTTTAAGGTGGATGAAGATGGCATGGTGT; ATGCCGTGAGAAGCTTTCCACTCTCTTCTGAGCATGCCAAGTTCCTGATATATGCCCAAG; ACAAAGAGACCCAGGAAAAGTGGCAAGTGGCAGTAAAATTGAGCCTGAAGCCAACCTTAA; CTGAGGAGTCAGTGAAGGAGTCAGCAGAAGTTGAAGAAATAGTGTTCCCAAGACAATTCA; GTAAGCACAGTGGCCACCTACAAAGGCAGAAGAGAGACTGGGTCATCCCTCCAATCAACT; TGCCAGAAAACTCCAGGGGACCTTTTCCTCAAGAGCTTGTCAGGATCAGGTCTGATAGAG; ATAAAAACCTTTCACTGCGGTACAGTGTAACTGGGCCAGGAGCTGACCAGCCTCCAACTG; GTATCTTCATTATCAACCCCATCTCGGGTCAGCTGTCGGTGACAAAGCCCCTGGATCGCG; AGCAGATAGCCCGGTTTCATTTGAGGGCACATGCAGTAGATATTAATGGAAATCAAGTGG; AGAACCCCATTGACATTGTCATCAATGTTATTGACATGAATGACAACAGACCTGAGTTCT; TACACCAGGTTTGGAATGGGACAGTTCCTGAGGGATCAAAGCCTGGAACATATGTGATGA; CCGTAACAGCAATTGATGCTGACGATCCCAATGCCCTCAATGGGATGTTGAGGTACAGAA; TCGTGTCTCAGGCTCCAAGCACCCCTTCACCCAACATGTTTACAATCAACAATGAGACTG; GTGACATCATCACAGTGGCAGCTGGACTTGATCGAGAAAAAGTGCAACAGTATACGTTAA; TAATTCAAGCTACAGACATGGAAGGCAATCCCACATATGGCCTTTCAAACACAGCCACGG; CCGTCATCACAGTGACAGATGTCAATGACAATCCTCCAGAGTTTACTGCCATGACGTTTT; ATGGTGAAGTTCCTGAGAACAGGGTAGACATCATAGTAGCTAATCTAACTGTGACCGATA; AGGATCAACCCCATACACCAGCCTGGAACGCAGTGTACAGAATCAGTGGCGGAGATCCTA; CTGGACGGTTCGCCATCCAGACCGACCCAAACAGCAACGACGGGTTAGTCACCGTGGTCA; AACCAATCGACTTTGAAACAAATAGGATGTTTGTCCTTACTGTTGCTGCAGAAAATCAAG; TGCCATTAGCCAAGGGAATTCAGCACCCGCCTCAGTCAACTGCAACCGTGTCTGTTACAG; TTATTGACGTAAATGAAAACCCTTATTTTGCCCCCAATCCTAAGATCATTCGCCAAGAAG; AAGGGCTTCATGCCGGTACCATGTTGACAACATTCACTGCTCAGGACCCAGATCGATATA; TGCAGCAAAATATTAGATACACTAAATTATCTGATCCTGCCAATTGGCTAAAAATAGATC; CTGTGAATGGACAAATAACTACAATTGCTGTTTTGGACCGAGAATCACCAAATGTGAAAA; ACAATATATATAATGCTACTTTCCTTGCTTCTGACAATGGAATTCCTCCTATGAGTGGAA; CAGGAACGCTGCAGATCTATTTACTTGATATTAATGACAATGCCCCTCAAGTGTTACCTC; AAGAGGCAGAGACTTGCGAAACTCCAGACCCCAATTCAATTAATATTACAGCACTTGATT; ATGACATTGATCCAAATGCTGGACCATTTGCTTTTGATCTTCCTTTATCTCCAGTGACTA; TTAAGAGAAATTGGACCATCACTCGGCTTAATGGTGATTTTGCTCAGCTTAATTTAAAGA; TAAAATTTCTTGAAGCTGGTATCTATGAAGTTCCCATCATAATCACAGATTCGGGTAATC; CTCCCAAATCAAATATTTCCATCCTGCGCGTGAAGGTTTGCCAGTGTGACTCCAACGGGG; ACTGCACAGATGTGGACAGGATTGTGGGTGCGGGGCTTGGCACCGGTGCCATCATTGCCA; TCCTGCTCTGCATCATCATCCTGCTTATCCTTGTGCTGATGTTTGTGGTATGGATGAAAC; GCCGGGATAAAGAACGCCAGGCCAAACAACTTTTAATTGATCCAGAAGATGATGTAAGAG; ATAATATTTTAAAATATGATGAAGAAGGTGGAGGAGAAGAAGACCAGGACTATGACTTGA; GCCAGCTGCAGCAGCCTGACACTGTGGAGCCTGATGCCATCAAGCCTGTGGGAATCCGAC; GAATGGATGAAAGACCCATCCACGCCGAGCCCCAGTATCCGGTCCGATCTGCAGCCCCAC; ACCCTGGAGACATTGGGGACTTCATTAATGAGGGCCTTAAAGCGGCTGACAATGACCCCA; CAGCTCCACCATATGACTCCCTGTTAGTGTTTGACTATGAAGGCAGTGGCTCCACTGCTG; GGTCCTTGAGCTCCCTTAATTCCTCAAGTAGTGGTGGTGAGCAGGACTATGATTACCTGA; ACGACTGGGGGCCACGGTTCAAGAAACTTGCTGACATGTATGGTGGAGGTGATGACTGAA; CTTCAGGGTGAACTTGGTTTTTGGACAAGTACAAACAATTTCAACTGATATTCCCAAAAA; GCATTCAGAAGCTAGGCTTTAACTTTGTAGTCTACTAGCACAGTGCTTGCTGGAGGCTTT; GGCATAGGCTGCAAACCAATTTGGGCTCAGAGGGAATATCAGTGATCCATACTGTTTGGA; AAAACACTGAGCTCAGTTACACTTGAATTTTACAGTACAGAAGCACTGGGATTTTATGTG; CCTTTTTGTACCTTTTTCAGATTGGAATTAGTTTTCTGTTTAAGGCTTTAATGGTACTGA; TTTCTGAAACGATAAGTAAAAGACAAAATATTTTGTGGTGGGAGCAGTAAGTTAAACCAT; GATATGCTTCAACACGCTTTTGTTACATTGCATTTGCTTTTATTAAAATACAAAATTAAA; CAAACAAAAAAACTCATGGAGCGATTTTATTATCTTGGGGGATGAGACCATGAGATTGGA; AAATGTACATTACTTCTAGTTTTAGACTTTAGTTTGTTTTTTTTTTTTCACTAAAATCTT; AAAACTTACTCAGCTGGTTGCAAATAAAGGGAGTTTTCATATCACCAATTTGTAGCAAAA; TTGAATTTTTTCATAAACTAGAATGTTAGACACATTTTGGTCTTAATCCATGTACACTTT; TTTATTTCTGTATTTTTCCACTTCACTGTAAAAATAGTATGTGTACATAATGTTTTATTG; GCATAGTCTATGGAGAAGTGCAGAAACTTCAGAACATGTGTATGTATTATTTGGACTATG; GATTCAGGTTTTTTGCATGTTTATATCTTTCGTTATGGATAAAGTATTTACAAAACAGTG; ACATTTGATTCAATTGTTGAGCTGTAGTTAGAATACTCAATTTTTAATTTTTTTAATTTT; TTTATTTTTTATTTTCTTTTTGGTTTGGGGAGGGAGAAAAGTTCTTAGCACAAATGTTTT; ACATAATTTGTACCAAAAAAAAAAAAAAGGAAAGGAAAGAAAGGGGTGGCCTGACACTGG; TGGCACTACTAAGTGTGTGTTTTTTTAAAAAAAAAATGGAAAAAAAAAGCTTTTAAACTG; GAGAGACTTCTGACAACAGCTTTGCCTCTGTATTGTGTACCAGAATATAAATGATACACC; TCTGACCCCAGCGTTCTGAATAAAATGCTAATTTTGGAAAAAAAAAAAAAAAAAACTCGA; C;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001792 unedited; TCCCCCGCCCCGTTGNCGCAAAGGGCGGTAGGCGTGTACGGTGGNGAGTCTATATAAGCA; GAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGA; ATTCGGCACGAGGGCTGCCGCTGCCTCCTCCTCCTCCGCCGCCGCCGCCGCCGCCGCCGC; CTCCTCCGGCTCTTCGCTCGGCCCCTCTCCGCCTCCATGTGCCGGATAGCGGGAGCGCTG; CGGACCCTGCTGCCGCTGCTGGCGGCCCTGCTTCAGGCGTCTGTAGAGGCTTCTGGTGAA; ATCGCATTATGCAAGACTGGATTTCCTGAAGATGTTTACAGTGCAGTCTTATCGAAGGAT; GTGCATGAAGGACAGCCTCTTCTCAATGTGAAGTTTAGCAACTGCAATGGAAAAAGAAAA; GTACAATATGAGAGCAGTGAGCCTGCAGATTTTAAGGTGGATGAAGATGGCATGGTGTAT; GCCGTGAGAAGCTTTCCACTCTCTTCTGAGCATGCCAAGTTCCTGATATATGCCCAAGAC; AAAGAGACCCAGGAAAAGTGGCAAGTGGCAGTAAAATTGAGCCTGAAGCCAACCTTAACT; GAGGAGTCAGTGAAGGAGTCAGCAGAAGTTGAAGAAATAGTGTTCCCAAGACAATTCAGT; AAGCACAGTGGCCACCTACAAAGGCAGAAGAGAGACTGGGTCATCCCTCCAATCAACTTG; CCAGAAAACTCCAGGGGACCTTTTCCTCAAGAGCTTGTCAGGATCAGGTCTGATAGAGAT; AAAAACCTTTCACTGCGGTACAGTGTAACTGGGCCCAGAGCTGACCAGCCTCCAACTGGG; TATCTCATTATCAACCCCATCTCGGGTCAGCTGTNCGTGACAAACCCCTGGTCGCGAGCA; GAAGCCCGGTTTNCATTGANGCACATGCAGTAGATATTAATGGAAATCAGTGGAGAACCC; CATGNACTTGA;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001792 unedited; GGGGGAGACTACNGGGTACCGTGGCCCGCATCNGGGGTACGAGTTTATTTCTTTTTTTTT; GTCCAAAATTAGCATTTTATTCAGAACGCTGGGGTCAGCGGTGTATCATTTATATTCTGG; TACACAATACAGAGGCAAAGCTGTTGTCAGAAGTCTCTCCAGTTTAAAAGCTTTTTTTTT; CCATTTTTTTTTTAAAAAAACACACACTTAGTAGTGCCACCAGTGTCAGGCCACCCCTTT; CTTTCCTTTCCTTTTTTTTTTTTTTGGTACAAATTATGTAAAACATTTGTGCTAAGAACT; TTTCTCCCTCCCCAAACCAAAAAGAAAATAAAAAATAAAAAAATTAAAAAAATTAAAAAT; TGAGTATTCTAACTACAGCTCAACAATTGAATCAAATGTCACTGTTTTGTAAATACTTTA; TCCATAACGAAAGATATAAACATGCAAAAAACCTGAATCCATAGTCCAAATAATACATAC; ACATGTTCTGAAGTTTCTGCACTTCTCCATAGACTATGCCAATAAAACATTATGTACACA; TACTATTTTTACAGTGAAGTGGAAAAATACAGAAATAAAAAAGTGTACATGGATTAAGAC; CAAAATGTGTCTAACATTCTAGTTTATGAAAAAATTCAATTTTGCTACAAATTGGTGATA; TGAAAACTCCCTTTATTTGCAACCAGCTGAGTAAGTTTTAAGATTTTAGTGAAAAAAAAA; AAACAACTTAAGTCTAAAACTAGAAGTAATGTACATTTTTCAATCTCATGGTCTCATCCC; CCAAGAAATAAAATCGCTCCATGAGTTTTTTGGTTTGGTAAATTTTGGATTTTAAAAAAA; GCAAATGCCATGTTACAAAAGCGTGTTGAAGCCTTTCATGGTTTAACTTACTGTTCCCCC;
• Restriction Sites: NotI-NotI
• ACCN: NM_001792
• Insert Size: 4500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001792.2, NP_001783.2
• RefSeq Size: 4122 bp
• RefSeq ORF: 2721 bp
• Locus ID: 1000
• UniProt ID: P19022
• Cytogenetics: 18q12.1
• Domains: CA, Cadherin_C_term
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs)
• Summary: This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015]; Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).