Cathepsin E (CTSE) (NM_001910) Human Untagged Clone

SKU SC118937

CTSE (untagged)-Human cathepsin E (CTSE), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: Cathepsin E
• Synonyms: CATE
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118937 sequence for NM_001910 edited (data generated by NextGen Sequencing); ATGAAAACGCTCCTTCTTTTGCTGCTGGTGCTCCTGGAGCTGGGAGAGGCCCAAGGATCC; CTTCACAGGGTGCCCCTCAGGAGGCATCCGTCCCTCAAGAAGAAGCTGCGGGCACGGAGC; CAGCTCTCTGAGTTCTGGAAATCCCATAATTTGGACATGATCCAGTTCACCGAGTCCTGC; TCAATGGACCAGAGTGCCAAGGAACCCCTCATCAACTACTTGGATATGGAATACTTCGGC; ACTATCTCCATTGGCTCCCCACCACAGAACTTCACTGTCATCTTCGACACTGGCTCCTCC; AACCTCTGGGTCCCCTCTGTGTACTGCACTAGCCCAGCCTGCAAGACGCACAGCAGGTTC; CAGCCTTCCCAGTCCAGCACATACAGCCAGCCAGGTCAATCTTTCTCCATTCAGTATGGA; ACCGGGAGCTTGTCCGGGATCATTGGAGCCGACCAAGTCTCTGTGGAAGGACTAACCGTG; GTTGGCCAGCAGTTTGGAGAAAGTGTCACAGAGCCAGGCCAGACCTTTGTGGATGCAGAG; TTTGATGGAATTCTGGGCCTGGGATACCCCTCCTTGGCTGTGGGAGGAGTGACTCCAGTA; TTTGACAACATGATGGCTCAGAACCTGGTGGACTTGCCGATGTTTTCTGTCTACATGAGC; AGTAACCCAGAAGGTGGTGCGGGGAGCGAGCTGATTTTTGGAGGCTACGACCACTCCCAT; TTCTCTGGGAGCCTGAATTGGGTCCCAGTCACCAAGCAAGCTTACTGGCAGATTGCACTG; GATAACATCCAGGTGGGAGGCACTGTTATGTTCTGCTCCGAGGGCTGCCAGGCCATTGTG; GACACAGGGACTTCCCTCATCACTGGCCCTTCCGACAAGATTAAGCAGCTGCAAAACGCC; ATTGGGGCAGCCCCCGTGGATGGAGAATATGCTGTGGAGTGTGCCAACCTTAACGTCATG; CCGGATGTCACCTTCACCATTAACGGAGTCCCCTATACCCTCAGCCCAACTGCCTACACC; CTACTGGACTTCGTGGATGGAATGCAGTTCTGCAGCAGTGGCTTTCAAGGACTTGACATC; CACCCTCCAGCTGGGCCCCTCTGGATCCTGGGGGATGTCTTCATTCGACAGTTTTACTCA; GTCTTTGACCGTGGGAATAACCGTGTGGGACTGGCCCCAGCAGTCCCCTAA; ; Clone variation with respect to NM_001910.3;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001910 unedited; GCATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACCAGAGAAGCTGCTG; GTCGGACTCACAATGAAAACGCTCCTTCTTTTGCTGCTGGTGCTCCTGGAGCTGGGAGAG; GCCCAAGGATCCCTTCACAGGGTGCCCCTCAGGAGGCATCCGTCCCTCAAGAAGAAGCTG; CGGGCACGGAGCCAGCTCTCTGAGTTCTGGAAATCCCATAATTTGGACATGATCCAGTTC; ACCGAGTCCTGCTCAATGGACCAGAGTGCCAAGGAACCCCTCATCAACTACTTGGATATG; GAATACTTCGGCACTATCTCCATTGGCTCCCCACCACAGAACTTCACTGTCATCTTCGAC; ACTGGCTCCTCCAACCTCTGGGTCCCCTCTGTGTACTGCACTAGCCCAGCCTGCAAGACG; CACAGCAGGTTCCAGCCTTCCCAGTCCAGCACATACAGCCAGCCAGGTCAATCTTTCTCC; ATTCAGTATGGAACCGGGAGCTTGTCCGGGATCATTGGAGCCGACCAAGTCTCTGTGGAA; GGACTAACCGTGGTTGGCCAGCAGTTTGGAGAAAGTGTCACAGAGCCAGGCCAGACCTTT; GTGGACGCAGAGTTTGATGGAATTCTGGGCCTGGGATACCCCTCCTTGGCTGTGGGAGGA; GTGACTCCAGTATTTGACAACATGATGGCTCAGAACCTGGTGGACTGNCCGATGTTTTCT; GTCTACTGAGCAGTANCCANAAGGGGNTGCGGNGAGCGAGCTGATTTTTGGGAGCTACGA; CCACTCCATTTCTCTGGAGCCTGAAATTGGTCCCAGTCACAGCAGCTACTGGCGATGCCT; GACTCGAGGGGGGGGGGGGGNTTNNNNNNNNNNNNNGGGGGGGGGGGNNNNNNNNNGGGG; GGNNNGGGGTTTTNTTGTGGTGGGCTCTTCAAAAATATGCATTGCACGCTCTGGGGCCCC; CCCGGGGGG;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001910 unedited; GCGGGCGGCACCGCACCCCCCCTTTCCCCCNNGGNNTTAGCTTGANACCACGGCCCGCTT; CTTANGANCGNGTTTTTTTCTTTTTTTTTTTNCTAACTACCATTTTTTAGGAAAAGAAAG; TTCAGGAGACCATGTCAAATGACACCTCGGGATTTCAACCAGCAACGTTCAAATGTGCTA; AACTCTGTAGATGGAAAGAGACTTACAGACATTTCAAATAAATGCAATATATGGGCCTTG; CTTGAATCCTAATACAAACAATCCAACTACAAAAACAGCCAAACATTTGTGGGACAATGG; GAGATGCTTGAATTCCGATTGTATATTTAAGGATGTTAGAAATATTTATGGACAAAATGA; TGTAATGCTCGGAATTTGCTTCAAAATGATCCAGGTACAGCATGTGGAGCTGGAGAGAGG; AGTGGGCAGCAGTGTAAATAAACAGGCCTGGCCGTGTGTGGATGGTTTGTCAGGGCTGAG; TGGAGTTGCAAAGGGATCTATTATACCATGATCTCTGCTTGTGCATATGTTTGGAGATTT; TCATAATCAAATGTGAAAATTTTTGATTTTCATAATCAAAAATCAATACCAAAATATGAA; TGTATAACGTAATTCCTCCATCATGACCGTGGTGGGAGTGGTGTGTATGTGTGAAGTGTG; AGTGTGTGTAATATGTGCGTGTGGGTGTGGATCCCCCAGGCCTGGTTGGCCTTAATTCAA; GTGCAACCCTGGAAACGGTACCTTCTTTGGAAAAAAACTTTTTGTAGTGAAAAAAATGCC; CACCTAAACTATTCAAGGTCTGCCAAAAAGGCAGGCCCACACCCAAGCCCCCTTCTTAGG; GGACTGTTTGGGCCCATACCAAACCGGTTTTCCCCCCGGCCAAGAATGGATAAAACGGCC; AATGAAAAAATTCTCCCAGATACCAAAGGGCCCACATTGGAGGTGGGATGTCAAGACCCT; TGAACCCACTGCTG;
• Restriction Sites: NotI-NotI
• ACCN: NM_001910
• Insert Size: 2190 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001910.2, NP_001901.1
• RefSeq Size: 2228 bp
• RefSeq ORF: 1191 bp
• Locus ID: 1510
• UniProt ID: P14091
• Cytogenetics: 1q32.1
• Domains: asp
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Lysosome
• Summary: This gene encodes a member of the A1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme, an aspartic endopeptidase, may be involved in antigen processing and the maturation of secretory proteins. Elevated expression of this gene has been observed in neurodegeneration. [provided by RefSeq, Nov 2015]; Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).