Cathepsin E (CTSE) (NM_001910) Human Untagged Clone

CAT#: SC118937

CTSE (untagged)-Human cathepsin E (CTSE), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Cathepsin E
• Synonyms: CATE
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118937 sequence for NM_001910 edited (data generated by NextGen Sequencing)
  ATGAAAACGCTCCTTCTTTTGCTGCTGGTGCTCCTGGAGCTGGGAGAGGCCCAAGGATCC
  CTTCACAGGGTGCCCCTCAGGAGGCATCCGTCCCTCAAGAAGAAGCTGCGGGCACGGAGC
  CAGCTCTCTGAGTTCTGGAAATCCCATAATTTGGACATGATCCAGTTCACCGAGTCCTGC
  TCAATGGACCAGAGTGCCAAGGAACCCCTCATCAACTACTTGGATATGGAATACTTCGGC
  ACTATCTCCATTGGCTCCCCACCACAGAACTTCACTGTCATCTTCGACACTGGCTCCTCC
  AACCTCTGGGTCCCCTCTGTGTACTGCACTAGCCCAGCCTGCAAGACGCACAGCAGGTTC
  CAGCCTTCCCAGTCCAGCACATACAGCCAGCCAGGTCAATCTTTCTCCATTCAGTATGGA
  ACCGGGAGCTTGTCCGGGATCATTGGAGCCGACCAAGTCTCTGTGGAAGGACTAACCGTG
  GTTGGCCAGCAGTTTGGAGAAAGTGTCACAGAGCCAGGCCAGACCTTTGTGGATGCAGAG
  TTTGATGGAATTCTGGGCCTGGGATACCCCTCCTTGGCTGTGGGAGGAGTGACTCCAGTA
  TTTGACAACATGATGGCTCAGAACCTGGTGGACTTGCCGATGTTTTCTGTCTACATGAGC
  AGTAACCCAGAAGGTGGTGCGGGGAGCGAGCTGATTTTTGGAGGCTACGACCACTCCCAT
  TTCTCTGGGAGCCTGAATTGGGTCCCAGTCACCAAGCAAGCTTACTGGCAGATTGCACTG
  GATAACATCCAGGTGGGAGGCACTGTTATGTTCTGCTCCGAGGGCTGCCAGGCCATTGTG
  GACACAGGGACTTCCCTCATCACTGGCCCTTCCGACAAGATTAAGCAGCTGCAAAACGCC
  ATTGGGGCAGCCCCCGTGGATGGAGAATATGCTGTGGAGTGTGCCAACCTTAACGTCATG
  CCGGATGTCACCTTCACCATTAACGGAGTCCCCTATACCCTCAGCCCAACTGCCTACACC
  CTACTGGACTTCGTGGATGGAATGCAGTTCTGCAGCAGTGGCTTTCAAGGACTTGACATC
  CACCCTCCAGCTGGGCCCCTCTGGATCCTGGGGGATGTCTTCATTCGACAGTTTTACTCA
  GTCTTTGACCGTGGGAATAACCGTGTGGGACTGGCCCCAGCAGTCCCCTAA
  
  Clone variation with respect to NM_001910.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001910 unedited
  GCATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACCAGAGAAGCTGCTG
  GTCGGACTCACAATGAAAACGCTCCTTCTTTTGCTGCTGGTGCTCCTGGAGCTGGGAGAG
  GCCCAAGGATCCCTTCACAGGGTGCCCCTCAGGAGGCATCCGTCCCTCAAGAAGAAGCTG
  CGGGCACGGAGCCAGCTCTCTGAGTTCTGGAAATCCCATAATTTGGACATGATCCAGTTC
  ACCGAGTCCTGCTCAATGGACCAGAGTGCCAAGGAACCCCTCATCAACTACTTGGATATG
  GAATACTTCGGCACTATCTCCATTGGCTCCCCACCACAGAACTTCACTGTCATCTTCGAC
  ACTGGCTCCTCCAACCTCTGGGTCCCCTCTGTGTACTGCACTAGCCCAGCCTGCAAGACG
  CACAGCAGGTTCCAGCCTTCCCAGTCCAGCACATACAGCCAGCCAGGTCAATCTTTCTCC
  ATTCAGTATGGAACCGGGAGCTTGTCCGGGATCATTGGAGCCGACCAAGTCTCTGTGGAA
  GGACTAACCGTGGTTGGCCAGCAGTTTGGAGAAAGTGTCACAGAGCCAGGCCAGACCTTT
  GTGGACGCAGAGTTTGATGGAATTCTGGGCCTGGGATACCCCTCCTTGGCTGTGGGAGGA
  GTGACTCCAGTATTTGACAACATGATGGCTCAGAACCTGGTGGACTGNCCGATGTTTTCT
  GTCTACTGAGCAGTANCCANAAGGGGNTGCGGNGAGCGAGCTGATTTTTGGGAGCTACGA
  CCACTCCATTTCTCTGGAGCCTGAAATTGGTCCCAGTCACAGCAGCTACTGGCGATGCCT
  GACTCGAGGGGGGGGGGGGGNTTNNNNNNNNNNNNNGGGGGGGGGGGNNNNNNNNNGGGG
  GGNNNGGGGTTTTNTTGTGGTGGGCTCTTCAAAAATATGCATTGCACGCTCTGGGGCCCC
  CCCGGGGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001910 unedited
  GCGGGCGGCACCGCACCCCCCCTTTCCCCCNNGGNNTTAGCTTGANACCACGGCCCGCTT
  CTTANGANCGNGTTTTTTTCTTTTTTTTTTTNCTAACTACCATTTTTTAGGAAAAGAAAG
  TTCAGGAGACCATGTCAAATGACACCTCGGGATTTCAACCAGCAACGTTCAAATGTGCTA
  AACTCTGTAGATGGAAAGAGACTTACAGACATTTCAAATAAATGCAATATATGGGCCTTG
  CTTGAATCCTAATACAAACAATCCAACTACAAAAACAGCCAAACATTTGTGGGACAATGG
  GAGATGCTTGAATTCCGATTGTATATTTAAGGATGTTAGAAATATTTATGGACAAAATGA
  TGTAATGCTCGGAATTTGCTTCAAAATGATCCAGGTACAGCATGTGGAGCTGGAGAGAGG
  AGTGGGCAGCAGTGTAAATAAACAGGCCTGGCCGTGTGTGGATGGTTTGTCAGGGCTGAG
  TGGAGTTGCAAAGGGATCTATTATACCATGATCTCTGCTTGTGCATATGTTTGGAGATTT
  TCATAATCAAATGTGAAAATTTTTGATTTTCATAATCAAAAATCAATACCAAAATATGAA
  TGTATAACGTAATTCCTCCATCATGACCGTGGTGGGAGTGGTGTGTATGTGTGAAGTGTG
  AGTGTGTGTAATATGTGCGTGTGGGTGTGGATCCCCCAGGCCTGGTTGGCCTTAATTCAA
  GTGCAACCCTGGAAACGGTACCTTCTTTGGAAAAAAACTTTTTGTAGTGAAAAAAATGCC
  CACCTAAACTATTCAAGGTCTGCCAAAAAGGCAGGCCCACACCCAAGCCCCCTTCTTAGG
  GGACTGTTTGGGCCCATACCAAACCGGTTTTCCCCCCGGCCAAGAATGGATAAAACGGCC
  AATGAAAAAATTCTCCCAGATACCAAAGGGCCCACATTGGAGGTGGGATGTCAAGACCCT
  TGAACCCACTGCTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001910
• Insert Size: 2190 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001910.2, NP_001901.1
• RefSeq Size: 2228 bp
• RefSeq ORF: 1191 bp
• Locus ID: 1510
• UniProt ID: P14091
• Cytogenetics: 1q32.1
• Domains: asp
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Lysosome
• Gene Summary: This gene encodes a member of the A1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme, an aspartic endopeptidase, may be involved in antigen processing and the maturation of secretory proteins. Elevated expression of this gene has been observed in neurodegeneration. [provided by RefSeq, Nov 2015]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).