FNTA (NM_002027) Human Untagged Clone

CAT#: SC118855

FNTA (untagged)-Human farnesyltransferase, CAAX box, alpha (FNTA), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FNTA
• Synonyms: FPTA; PGGT1A; PTAR2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_002027, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGCCACCGAGGGGGTCGGGGAGGCTGCGCAAGGGGGCGAGCCCGGGCAGCCGGCGCAACCCCCGC
  CCCAGCCGCACCCACCGCCGCCCCAGCAGCAGCACAAGGAAGAGATGGCGGCCGAGGCTGGGGAAGCCGT
  GGCGTCCCCCATGGACGACGGGTTTGTGAGCCTGGACTCGCCCTCCTATGTCCTGTACAGGGACAGAGCA
  GAATGGGCTGATATAGATCCGGTGCCGCAGAATGATGGCCCCAATCCCGTGGTCCAGATCATTTATAGTG
  ACAAATTTAGAGATGTTTATGATTACTTCCGAGCTGTCCTGCAGCGTGATGAAAGAAGTGAACGAGCTTT
  TAAGCTAACCCGGGATGCTATTGAGTTAAATGCAGCCAATTATACAGTGTGGCATTTCCGGAGAGTTCTT
  TTGAAGTCACTTCAGAAGGATCTACATGAGGAAATGAACTACATCACTGCAATAATTGAGGAGCAGCCCA
  AAAACTATCAAGTTTGGCATCATAGGCGAGTATTAGTGGAATGGCTAAGAGATCCATCTCAGGAGCTTGA
  ATTTATTGCTGATATTCTTAATCAGGATGCAAAGAATTATCATGCCTGGCAGCATCGACAATGGGTTATT
  CAGGAATTTAAACTTTGGGATAATGAGCTGCAGTATGTGGACCAACTTCTGAAAGAGGATGTGAGAAATA
  ACTCTGTCTGGAACCAAAGATACTTCGTTATTTCTAACACCACTGGCTACAATGATCGTGCTGTATTGGA
  GAGAGAAGTCCAATACACTCTGGAAATGATTAAACTAGTACCACATAATGAAAGTGCATGGAACTATTTG
  AAAGGGATTTTGCAGGATCGTGGTCTTTCCAAATATCCTAATCTGTTAAATCAATTACTTGATTTACAAC
  CAAGTCATAGTTCCCCCTACCTAATTGCCTTTCTTGTGGATATCTATGAAGACATGCTAGAAAATCAGTG
  TGACAATAAGGAAGACATTCTTAATAAAGCATTAGAGTTATGTGAAATCCTAGCTAAAGAAAAGGACACT
  ATAAGAAAGGAATATTGGAGATACATTGGAAGATCCCTTCAAAGCAAACACAGCACAGAAAATGACTCAC
  CAACAAATGTACAGCAATAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002027 unedited
  TTCGAATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGGCGAGATGGCG
  GCCACCGAGGGGGTCGGGGAGGCTGCGCAGGGGGCGAGCCCGGGCAGCCGGCGCAACCCC
  CGCCCCAGCCGCACCCACCGCCGCCCCAGCAGCAGCACAAGGAAGAGATGGCGGCCGAGG
  CTGGGGAAGCCGTGGCGTCCCCCATGGACGACGGGTTTGTGAGCCTGGACTCGCCCTCCT
  ATGTCCTGTACAGGGACAGAGCAGAATGGGCTGATATAGATCCGGTGCCGCAGAATGATG
  GCCCCAATCCCGTGGTCCAGATCATTTATAGTGACAAATTTAGAGATGTTTATGATTACT
  TCCGAGCTGTCCTGCAGCGTGATGAAAGAAGTGAACGAGCTTTTAAGCTAACCCGGGATG
  CTATTGAGTTAAATGCAGCCAATTATACAGTGTGGCATTTCCGGAGAGTTCTTTTGAAGT
  CACTTCAGAAGGATCTACATGAGGAAATGAACTACATCACTGCAATAATTGAGGAGCAGC
  CCAAAAACTATCAAGTTTGGCATCATAGGCGAGTATTAGTGGAATGGCTAAGAGATCCAT
  CTCAGGAGCTTGAATTTATTGCTGATATTCTTAATCAGGATGCAAAGAATTATCATGCCT
  GGCAGCATCGACAATGGGTTATTCAGGAATTTAAACTTTGGGATAATGAGCTGCAGTATG
  TGGACCAACTTCTGAAAGAGGATGTGAGAAATAACTCTGTCTGGAACCAAAGATACTTCG
  TTATTTCTAACACCACTGGCTACAATGATCGTGCTGTATTGGANAGAGAAAGTCCATACA
  CTCTGGNAATGATTAAACTAGTACCACATAATGGAAGTGCATGGAACTATNTGAAAAGGG
  ATTTGCAGNATCGTGGTCCTTCCCAN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002027 unedited
  ATGGCAACTTCCAGTGCCAGNAAAGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGAT
  CTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTT
  TTTAGATACAGCTATAATTTTATTACAAAACCGTTCTTTTGGCATTAGTTGGTTACAGTG
  ATAGCAAGATAATGTGAGTGTGCAGACCAGCTCTGATGGAACGACTGTATTCCCTGCTTA
  CTGAACCAAACTTCGGCTACCTCACATCCATTACATACAAGTGACCTGCAGTTATTACTG
  CTACAAATCTTGACGCATGTACCACTGAGGGAGGAGCTGATGCTAAGGGATTAGATTATA
  TGTTGATAAGACTACAAAAGTTCCTTTATGGGACTTTTTCTTCCTCCTCCCATCCAATGA
  CTTTGCTTTAGAAGAATCACATTACTTAGAGCTAGTCTGAGTAGCAGCAGCACCCAAGGA
  GCATCAGTTCTTGTTAAAAAGCAATACCTGTGTGATGCACTTTTACACCACAGGCAAAGG
  GAAGGACCACTCTCGTGTGAAACTCCTGCAGGGTCCCTTAATAAAAAATAAAAGCATTCC
  ATCAAGTTCTTCTGGATGGTGTTATTGCTGTACATTTGTTGGTGAGTCATTTTCTGTGCT
  GTGTTTGCTTTGAAGGGATCTTNNCATGTATCTNCAATATTCCTTTCTTATAGTGTCCTT
  TTCTTTAGCTAGGATTTCACATAACTCTAATGCTTTATTAAGAATGTCTTCCTTTATTGC
  ACACTGATTTTCTAGCATGTCTTCATANTATCCACAAGAAAGCATTTAGTAGGGGGAACT
  TGACCTGGTTGTAATCAAGTAATGATTACAGATANGATTTTGGAAGACACCATCTGC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002027
• Insert Size: 1530 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002027.2, NP_002018.1
• RefSeq Size: 1710 bp
• RefSeq ORF: 1140 bp
• Locus ID: 2339
• UniProt ID: P49354
• Cytogenetics: 8p11.21
• Domains: PPTA
• Protein Families: Druggable Genome
• Gene Summary: Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, May 2010]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein.