FNTA (NM_002027) Human Untagged Clone

SKU SC118855

FNTA (untagged)-Human farnesyltransferase, CAAX box, alpha (FNTA), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: FNTA
• Synonyms: FPTA; PGGT1A; PTAR2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_002027, the custom clone sequence may differ by one or more nucleotides; ; ; ATGGCGGCCACCGAGGGGGTCGGGGAGGCTGCGCAAGGGGGCGAGCCCGGGCAGCCGGCGCAACCCCCGC; CCCAGCCGCACCCACCGCCGCCCCAGCAGCAGCACAAGGAAGAGATGGCGGCCGAGGCTGGGGAAGCCGT; GGCGTCCCCCATGGACGACGGGTTTGTGAGCCTGGACTCGCCCTCCTATGTCCTGTACAGGGACAGAGCA; GAATGGGCTGATATAGATCCGGTGCCGCAGAATGATGGCCCCAATCCCGTGGTCCAGATCATTTATAGTG; ACAAATTTAGAGATGTTTATGATTACTTCCGAGCTGTCCTGCAGCGTGATGAAAGAAGTGAACGAGCTTT; TAAGCTAACCCGGGATGCTATTGAGTTAAATGCAGCCAATTATACAGTGTGGCATTTCCGGAGAGTTCTT; TTGAAGTCACTTCAGAAGGATCTACATGAGGAAATGAACTACATCACTGCAATAATTGAGGAGCAGCCCA; AAAACTATCAAGTTTGGCATCATAGGCGAGTATTAGTGGAATGGCTAAGAGATCCATCTCAGGAGCTTGA; ATTTATTGCTGATATTCTTAATCAGGATGCAAAGAATTATCATGCCTGGCAGCATCGACAATGGGTTATT; CAGGAATTTAAACTTTGGGATAATGAGCTGCAGTATGTGGACCAACTTCTGAAAGAGGATGTGAGAAATA; ACTCTGTCTGGAACCAAAGATACTTCGTTATTTCTAACACCACTGGCTACAATGATCGTGCTGTATTGGA; GAGAGAAGTCCAATACACTCTGGAAATGATTAAACTAGTACCACATAATGAAAGTGCATGGAACTATTTG; AAAGGGATTTTGCAGGATCGTGGTCTTTCCAAATATCCTAATCTGTTAAATCAATTACTTGATTTACAAC; CAAGTCATAGTTCCCCCTACCTAATTGCCTTTCTTGTGGATATCTATGAAGACATGCTAGAAAATCAGTG; TGACAATAAGGAAGACATTCTTAATAAAGCATTAGAGTTATGTGAAATCCTAGCTAAAGAAAAGGACACT; ATAAGAAAGGAATATTGGAGATACATTGGAAGATCCCTTCAAAGCAAACACAGCACAGAAAATGACTCAC; CAACAAATGTACAGCAATAA; ;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002027 unedited; TTCGAATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGGCGAGATGGCG; GCCACCGAGGGGGTCGGGGAGGCTGCGCAGGGGGCGAGCCCGGGCAGCCGGCGCAACCCC; CGCCCCAGCCGCACCCACCGCCGCCCCAGCAGCAGCACAAGGAAGAGATGGCGGCCGAGG; CTGGGGAAGCCGTGGCGTCCCCCATGGACGACGGGTTTGTGAGCCTGGACTCGCCCTCCT; ATGTCCTGTACAGGGACAGAGCAGAATGGGCTGATATAGATCCGGTGCCGCAGAATGATG; GCCCCAATCCCGTGGTCCAGATCATTTATAGTGACAAATTTAGAGATGTTTATGATTACT; TCCGAGCTGTCCTGCAGCGTGATGAAAGAAGTGAACGAGCTTTTAAGCTAACCCGGGATG; CTATTGAGTTAAATGCAGCCAATTATACAGTGTGGCATTTCCGGAGAGTTCTTTTGAAGT; CACTTCAGAAGGATCTACATGAGGAAATGAACTACATCACTGCAATAATTGAGGAGCAGC; CCAAAAACTATCAAGTTTGGCATCATAGGCGAGTATTAGTGGAATGGCTAAGAGATCCAT; CTCAGGAGCTTGAATTTATTGCTGATATTCTTAATCAGGATGCAAAGAATTATCATGCCT; GGCAGCATCGACAATGGGTTATTCAGGAATTTAAACTTTGGGATAATGAGCTGCAGTATG; TGGACCAACTTCTGAAAGAGGATGTGAGAAATAACTCTGTCTGGAACCAAAGATACTTCG; TTATTTCTAACACCACTGGCTACAATGATCGTGCTGTATTGGANAGAGAAAGTCCATACA; CTCTGGNAATGATTAAACTAGTACCACATAATGGAAGTGCATGGAACTATNTGAAAAGGG; ATTTGCAGNATCGTGGTCCTTCCCAN;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002027 unedited; ATGGCAACTTCCAGTGCCAGNAAAGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGAT; CTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTT; TTTAGATACAGCTATAATTTTATTACAAAACCGTTCTTTTGGCATTAGTTGGTTACAGTG; ATAGCAAGATAATGTGAGTGTGCAGACCAGCTCTGATGGAACGACTGTATTCCCTGCTTA; CTGAACCAAACTTCGGCTACCTCACATCCATTACATACAAGTGACCTGCAGTTATTACTG; CTACAAATCTTGACGCATGTACCACTGAGGGAGGAGCTGATGCTAAGGGATTAGATTATA; TGTTGATAAGACTACAAAAGTTCCTTTATGGGACTTTTTCTTCCTCCTCCCATCCAATGA; CTTTGCTTTAGAAGAATCACATTACTTAGAGCTAGTCTGAGTAGCAGCAGCACCCAAGGA; GCATCAGTTCTTGTTAAAAAGCAATACCTGTGTGATGCACTTTTACACCACAGGCAAAGG; GAAGGACCACTCTCGTGTGAAACTCCTGCAGGGTCCCTTAATAAAAAATAAAAGCATTCC; ATCAAGTTCTTCTGGATGGTGTTATTGCTGTACATTTGTTGGTGAGTCATTTTCTGTGCT; GTGTTTGCTTTGAAGGGATCTTNNCATGTATCTNCAATATTCCTTTCTTATAGTGTCCTT; TTCTTTAGCTAGGATTTCACATAACTCTAATGCTTTATTAAGAATGTCTTCCTTTATTGC; ACACTGATTTTCTAGCATGTCTTCATANTATCCACAAGAAAGCATTTAGTAGGGGGAACT; TGACCTGGTTGTAATCAAGTAATGATTACAGATANGATTTTGGAAGACACCATCTGC;
• Restriction Sites: NotI-NotI
• ACCN: NM_002027
• Insert Size: 1530 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002027.2, NP_002018.1
• RefSeq Size: 1710 bp
• RefSeq ORF: 1140 bp
• Locus ID: 2339
• UniProt ID: P49354
• Cytogenetics: 8p11.21
• Domains: PPTA
• Protein Families: Druggable Genome
• Summary: Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, May 2010]; Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein.