Galectin 3 (LGALS3) (NM_002306) Human Untagged Clone

CAT#: SC118706

LGALS3 (untagged)-Human lectin, galactoside-binding, soluble, 3 (LGALS3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Galectin 3
• Synonyms: CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002306 edited
  GAATTCGGCACCAGAGCAGCCGTCCGGAGCCAGCCAACGAGCGGAAAATGGCAGACAATT
  TTTCGCTCCATGATGCGTTATCTGGGTCTGGAAACCCAAACCCTCAAGGATGGCCTGGCG
  CATGGGGGAACCAGCCTGCTGGGGCAGGGGGCTACCCAGGGGCTTCCTATCCTGGGGCCT
  ACCCCGGGCAGGCACCCCCAGGGGCTTATCCTGGACAGGCACCTCCAGGCGCCTACCCTG
  GAGCACCTGGAGCTTATCCCGGAGCACCTGCACCTGGAGTCTACCCAGGGCCACCCAGCG
  GCCCTGGGGCCTACCCATCTTCTGGACAGCCAAGTGCCACCGGAGCCTACCCTGCCACTG
  GCCCCTATGGCGCCCCTGCTGGGCCACTGATTGTGCCTTATAACCTGCCTTTGCCTGGGG
  GAGTGGTGCCTCGCATGCTGATAACAATTCTGGGCACGGTGAAGCCCAATGCAAACAGAA
  TTGCTTTAGATTTCCAAAGAGGGAATGATGTTGCCTTCCACTTTAACCCACGCTTCAATG
  AGAACAACAGGAGAGTCATTGTTTGCAATACAAAGCTGGATAATAACTGGGGAAGGGAAG
  AAAGACAGTCGGTTTTCCCATTTGAAAGTGGGAAACCATTCAAAATACAAGTACTGGTTG
  AACCTGACCACTTCAAGGTTGCAGTGAATGATGCTCACTTGTTGCAGTACAATCATCGGG
  TTAAAAAACTCAATGAAATCAGCAAACTGGGAATTTCTGGTGACATAGACCTCACCAGTG
  CTTCATATACCATGATATAATCTGAAAGGGGCAGATTAAAAAAAAAAAAAAAAAAACTCG
  AC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002306 unedited
  NNNGGTTCGAATTTTGTAATACGACTCACTATAGGGCGGCNCGCGAATCGGCACCAGAGC
  AGCCGTCCGGAGCCAGCCAACGAGCGGAAAATGGCAGACAATTTTTCGCTCCATGATGCG
  TTATCTGGGTCTGGAAACCCAAACCCTCAAGGATGGCCTGGCGCATGGGGGAACCAGCCT
  GCTGGGGCAGGGGGCTACCCAGGGGCTTCCTATCCTGGGGCCTACCCCGGGCAGGCACCC
  CCAGGGGCTTATCCTGGACAGGCACCTCCAGGCGCCTACCCTGGAGCACCTGGAGCTTAT
  CCCGGAGCACCTGCACCTGGAGTCTACCCAGGGCCACCCAGCGGCCCTGGGGCCTACCCA
  TCTTCTGGACAGCCAAGTGCCACCGGAGCCTACCCTGCCACTGGCCCCTATGGCGCCCCT
  GCTGGGCCACTGATTGTGCCTTATAACCTGCCTTTGCCTGGGGGAGTGGTGCCTCGCATG
  CTGATAACAATTCTGGGCACGGTGAAGCCCAATGCAAACAGAATTGCTTTAGATTTCCAA
  AGAGGGAATGATGTTGCCTTCCACTTTAACCCACGCTTCAATGAGAACAACAGGAGAGTC
  ATTGTTTGCAATACAAAGCTGGATAATAACTGGGGAAGGGAAGAAAGACAGTCGGTTNTC
  CCATTTGAAAGTGGGAAACCATTCAAAATACAAGTACTGGGTTGAACCTGACCACTTCAA
  GGTTGCAGTGAATGATGCTCACTTGTTGCAGTACAATCATCGGGTTAAAAAACTCAATGA
  AAATCAGCAACTGGNGAATTTCTGGTGACATAGACCTCACCAGTGCTTCATATACCATGA
  TATAATCTGAAGGGGGGCAGATAAAAAAAAAAAAAAAACTCGCTCTAGATGCGGCCGCGT
  CATAGCTGTTCCTGAAAGATCCCGGTGGCATCCTGTGACC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002306 unedited
  GGGGGNNNNNGGGGGGGNNNNNNNNNNNNTNNNNNNNNNNNTTTTTGACTTTGNACCGCG
  GNCCCGCAACTAGNGATCGGTTTTTTTTTTTTTTTTTTTAATCTGCCCCTTTCAAATATA
  TCATGGTATATGAAGCACTGGTGAGGTCTATGTCACCAGAAATTCCCAGTTTGCTGATTT
  CATTGAGTTTTTTAACCCGATGATTGTACTGCAACAAGTGAGCATCATTCACTGCAACCT
  TGAAGTGGTCAGGTTCAACCAGTACTTGTATTTTGAATGGTTTCCCACTTTCAAATGGGA
  AAACCGACTGTCTTTCTTCCCTTCCCCAGTTATTATCCAGCTTTGTATTGCAAACAATGA
  CTCTCCTGTTGTTCTCATTGAAGCGTGGGTTAAAGTGGAAGGCAACATCATTCCCTCTTT
  GGAAATCTAAAGCAATTCTGTTTGCATTGGGCTTCACCGTGCCCAGAATTGTTATCAGCA
  TGCGAGGCACCACTCCCCCAGGCAAAGGCAGGTTATAAGGCACAATCAGTGGCCCAGCAG
  GGGCGCCATAGGGGCCAGTGGCAGGGTAGGCTCCGGTGGCACTTGGCTGTCCAGAAGATG
  GGTAGGCCCCAGGGCCGCTGGGTGGCCCTGGGTAGACTCCAGGTGCAGGTGCTCCGGGAT
  AAGCTCCAGGTGCTCCAGGGTAGGCGCCTGGAGGTGCCTGTCCAGGATAAGCCCCTTGGG
  GTGCCTGCCNCGGGTAGGCCCCAGGATAGGAAGCCCCCTGGTAGCCCCCTGCCCCAGCAG
  GCTGGTTCCCCCATGCGCCCAGCCATCCTTGAGGGNTTTGGTTNCCAGACCCAGATAACG
  CATCATGGAGCGAAAAAATGTCTGCCATTTTCCGCTCGTTGGCTGGCTCCGGACGGCTGC
  TCTTGTGCCCGAATTCCCGGNCCGCCCTATAGTGAGTCGTATTACN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002306
• Insert Size: 950 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002306.1, NP_002297.1
• RefSeq Size: 914 bp
• RefSeq ORF: 753 bp
• Locus ID: 3958
• UniProt ID: P17931
• Cytogenetics: 14q22.3
• Domains: Gal-bind_lectin
• Protein Families: Secreted Protein
• Gene Summary: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014]
  Transcript Variant: This variant (1) encodes isoform 1.