Superoxide Dismutase 3 (SOD3) (NM_003102) Human Untagged Clone

SKU SC118157

SOD3 (untagged)-Human superoxide dismutase 3, extracellular (SOD3)

Product Data

• Type: Human Untagged Clone
• Target Symbol: Superoxide Dismutase 3
• Synonyms: EC-SOD
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118157 sequence for NM_003102 edited (data generated by NextGen Sequencing); ATGCTGGCGCTACTGTGTTCCTGCCTGCTCCTGGCAGCCGGTGCCTCGGACGCCTGGACG; GGCGAGGACTCGGCGGAGCCCAACTCTGACTCGGCGGAGTGGATCCGAGACATGTACGCC; AAGGTCACGGAGATCTGGCAGGAGGTCATGCAGCGGCGGGACGACGACGGCACGCTCCAC; GCCGCCTGCCAGGTGCAGCCGTCGGCCACGCTGGACGCCGCGCAGCCCCGGGTGACCGGC; GTCGTCCTCTTCCGGCAGCTTGCGCCCCGCGCCAAGCTCGACGCCTTCTTCGCCCTGGAG; GGCTTCCCGACCGAGCCGAACAGCTCCAGCCGCGCCATCCACGTGCACCAGTTCGGGGAC; CTGAGCCAGGGCTGCGAGTCCACCGGGCCCCACTACAACCCGCTGGCCGTGCCGCACCCG; CAGCACCCGGGCGACTTCGGCAACTTCGCGGTCCGCGACGGCAGCCTCTGGAGGTACCGC; GCCGGCCTGGCCGCCTCGCTCGCGGGCCCGCACTCCATCGTGGGCCGGGCCGTGGTCGTC; CACGCTGGCGAGGACGACCTGGGCCGCGGCGGCAACCAGGCCAGCGTGGAGAACGGGAAC; GCGGGCCGGCGGCTGGCCTGCTGCGTGGTGGGCGTGTGCGGGCCCGGGCTCTGGGAGCGC; CAGGCGCGGGAGCACTCAGAGCGCAAGAAGCGGCGGCGCGAGAGCGAGTGCAAGGCCGCC; TGA; ; Clone variation with respect to NM_003102.2; 172 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003102 unedited; NTTTCAGGTCAGAATTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCTGG; GTGCAGCTCTCTTTTCAGGAGAGAAAGCTCTCTTGGAGGAGCTGGAAAGTGCCCGACTCC; AGCCATGCTGGCGCTACTGTGTTCCTGCCTGCTCCTGGCAGCCGGTGCCTCGGACGCCTG; GACGGGCGAGGACTCGGCGGAGCCCAACTCTGACTCGGCGGAGTGGATCCGAGACATGTA; CGCCAAGGTCACGGAGATCTGGCAGGAGGTCATGCAGCGGCGGGACGACGACGGCACGCT; CCACGCCGCCTGCCAGGTGCAGCCGTCGGCCACGCTGGACGCCGCGCAGCCCCGGGTGAC; CGGCGTCGTCCTCTTCCGGCAGCTTGCGCCCCGCGCCAAGCTCGACGCCTTCTTCGCCCT; GGAGGGCTTCCCGACCGAGCCGAACAGCTCCAGCCGCGCCATCCACGTGCACCAGTTCGG; GGACCTGAGCCAGGGCTGCGAGTCCACCGGGCCCCACTACAACCCGCTGGCCGTGCCGCA; CCCGCAGCACCCGGGCGACTTCGGCAACTTCGCGGTCCGCGACGGCAGCCTCTGGAGGTA; CCGCGCCGGCCTGGCCGCCTGNTNCGCGGGCCCGCACTCATNCGTGGGGCCGGGCCCGTG; GTCGTCCACGCTGGCGAGGACGACCTGNGCCGCGGCGGCAACCAGGCCAGCGTGGAGAAC; GGGAACGCGGGCCGGCGGCTGGCCTGCTGCGTGGTGGGCGTGTGCGGGCCCCGGCTCTGG; GAGCGCCAGGCGCCGGAGCACTCAGAGCGCAAGAAGCGGCGGCGCGAGAGCGAGTGCAAG; GCCGCCTGGACGCCGCCCCCACCCGGCGGCGGCCAGGGACCCCCGAGGC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003102 unedited; AAACAGCTATGACCGCGGCCGCAATCTATAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTT; TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGAAATGGGGAATTTTTAAACCGGA; ACCCAAAGGTTGCCAAACTTTCCCCCAAAGAAACCCCCCTCAGGGGGGGGGCGGGGGGTC; CCAAACACCTTAAAACCCCGGGGATTTGGCCTGGCTTCCCTTTCCCGGGCTGGCTTGCCC; CGGGAACGGGGGGG;
• Restriction Sites: NotI-NotI
• ACCN: NM_003102
• Insert Size: 1500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003102.1, NP_003093.1
• RefSeq Size: 1984 bp
• RefSeq ORF: 723 bp
• Locus ID: 6649
• UniProt ID: P08294
• Cytogenetics: 4p15.2
• Domains: sodcu
• Protein Families: Druggable Genome, Secreted Protein
• Summary: This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein, or type C subunit, exhibit high affinity for heparin and are anchored to the ECM. Homotetramers consisting of a proteolytically cleaved form of the protein, or type A subunit, exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk. [provided by RefSeq, Oct 2015]