Uridine Phosphorylase 1 (UPP1) (NM_003364) Human Untagged Clone

SKU SC118012

UPP1 (untagged)-Human uridine phosphorylase 1 (UPP1), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: Uridine Phosphorylase 1
• Synonyms: UDRPASE; UP; UPASE; UPP
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118012 sequence for NM_003364 edited (data generated by NextGen Sequencing); ATGGCGGCCACGGGAGCCAATGCAGAGAAAGCTGAAAGTCACAATGATTGCCCCGTCAGA; CTTTTAAATCCAAACATAGCAAAAATGAAAGAAGATATTCTCTATCATTTCAATCTCACC; ACTAGCAGACACAATTTCCCAGCCTTGTTTGGAGATGTGAAGTTTGTGTGTGTTGGTGGA; AGCCCCTCCCGGATGAAAGCCTTCATCAGGTGCGTTGGTGCAGAGCTGGGCCTTGACTGC; CCAGGTAGAGACTATCCCAACATCTGTGCGGGAACTGACCGCTATGCCATGTATAAAGTA; GGACCGGTGCTGTCTGTCAGTCATGGTATGGGCATTCCTTCTATCTCAATCATGTTGCAT; GAGCTCATAAAGCTGCTGTACTATGCCCGGTGCTCCAACGTCACTATCATCCGCATTGGC; ACTTCTGGTGGGATAGGTCTGGAGCCCGGCACTGTGGTCATAACAGAGCAGGCAGTGGAT; ACCTGCTTCAAGGCAGAGTTTGAGCAGATTGTCCTGGGGAAGCGGGTCATCCGGAAAACG; GACCTTAACAAGAAGCTGGTGCAGGAGCTGTTGCTGTGTTCTGCAGAGCTGAGCGAGTTC; ACCACAGTGGTGGGGAACACCATGTGCACCTTGGACTTCTATGAAGGGCAAGGCCGTCTG; GATGGGGCTCTCTGCTCCTACACGGAGAAGGACAAGCAGGCGTATCTGGAGGCAGCCTAT; GCAGCCGGCGTCCGCAATATCGAGATGGAGTCCTCGGTGTTTGCCGCCATGTGCAGCGCC; TGCGGCCTCCAAGCGGCCGTGGTGTGTGTCACCCTCCTGAACCGCCTGGAAGGGGACCAG; ATCAGCAGCCCTCGCAATGTGCTCAGCGAGTACCAGCAGAGGCCGCAGCGGCTGGTGAGC; TACTTCATCAAGAAGAAACTGAGCAAGGCCTGA; ; Clone variation with respect to NM_003364.2;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003364 unedited; GGGGGCCCCCCANNNCCTTCCNCNCCCCCTGTTCAAATTTGTNATACGACTCACTATAGG; CGGCCGCGAATTCGCACGAGGTTCCCTCATTCGAGTGCTCCGGCGCACAGACCCGCGCCC; CGCCGTCCGCGAGCCTCCCGAGAGCCGTCCCTTCGTCCGGCCCTGGAGCATTGCGTTTGT; CGCCGGTGTCGCAGTGCGAGGATGGCGCCGCGGGTGTAGCGGCTCTCTGCGCAGGCCGAG; TGGGCCCAGAGAAGCGAGGAACTCCGCAGCTCGTCGACACGTCTCGTCTCCTGTCCCAAT; TCAGGGCTTGGTGAGGTGACTCGCGGTCGCGGGTGACTCGCCGGCAGGACACTGCCTGGA; ACGCCTGGAGCGCCTCCCACTGCAGACGTCTGTCCGCCTCCAGCCGCTCTCCTCTGACGG; GTCCTGCCTCAGTTGGCGGAATGGCGGCCACGGGAGCCAATGCAGAGAAAGCTGAAAGTC; ACAATGATTGCCCCGTCAGACTTTTAAATCCAAACATAGCAAAAATGAAAGAAGATATTC; TCTATCATTTCAATCTCACCACTAGCAGACACAATTTCCCAGCCTTGTTTGGAGATGTGA; AGTTTGTGTGTGTTGGTGGAAGCCCCTCCCGGATGAAAGCCTTCATCANGTGCGTTGGTG; CAGAGCTGGGCCTTGACTGCCCAGNTAGAGACTATCCCAACATCTGTGCGGGAACTGACC; GCTATGCCATGTANTAAGTANGACCCGGTGCTGTCTGTCAGTCATGGTATGGGCATTCCT; TCTATCTCAATCATGGTGCATGAGCTCATAAAGCTGCTGTACTATGCCCNGGTGCTCCAC; GTCACTATCATCCCGCATTGGCACTTCTGGTGGGATAAGGNCTGAAGCCCGGCACTGTGG; TCATTACAGAGCAGGCAGTGGAATACCTGCTCAGGNCAAAGTTTGAGCANAATTGTCCTG; GGNAAGCGGGTCATCCCGGAAAACGGACCTTACAAGAAGCTGGTGCAGA;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003364 unedited; NGGGCCTTCTATGNACCGCGCCGCTTTCTAAGATCGATTTTTTTTTTTTTTTTTTTTTTT; TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGACAAAGCTTTTAATGGGAAGTCA; TCACAACAAGTCTGCGGAGGGGCAAGGGAACGCTCAAGCCCTGGTCAATTTTTTTTTGAA; GAAATAACTCACCAACCCCTGGGGCCCCTGGTGGGACCCGCTGAACACATTGGGAGGGCT; GGTGATTTGGTCCCCTTTCAAGCGGGTTAAGAGGGGGACACACACCCCCGCCCCTTGGAG; GCCCCAAGCCCCTCACATGGGGGGAAAAACCCAGGACCCCCTCTTGATTTTGGGGACCCC; CGCTGGATAAGCTGCCCCCAAAAACCCCCGGTTGTCCTTTTCCCGGTAGGAACAAAAAGC; CCCATTCAAAAAGGCTTGGCCTTTATAAAAATCCAAAGGGCCCATGGGGGTCCCCACCCC; TGGGGGGAAATCGCTCAACTTTGGAAAACAAAAAAACAACTTCTGGACCAACTTTTTGTT; AAAGGCCCTTTTCCGGATGAACCCCTTTCCCAAGACAAACTGGTCAAACTCTGCCCTGAA; ACAAGGATCCCCCGGCCGCTCTGGTATGAACACAATGGCCGGGTTCAGACCATCCCACCC; AAAATGCCCATGCCGATTATAATGACCTTTGAACACCCGGCATTATACCACAACTTTTTG; AACCCTGCCACATGGTTGGGAAAAAAAGAATGCCCCTTCCCTTGGTGGAAGAAAAAACCC; GGGCCCATTTTTTACATGGGATAACGGGCAATTTCCCCACAGATGGTGGGGAAATCCCTA; CCCGGGCAGATAAGGG;
• Restriction Sites: NotI-NotI
• ACCN: NM_003364
• Insert Size: 1250 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003364.2, NP_003355.1
• RefSeq Size: 1796 bp
• RefSeq ORF: 933 bp
• Locus ID: 7378
• UniProt ID: Q16831
• Cytogenetics: 7p12.3
• Domains: PNP_UDP_1
• Protein Pathways: Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism
• Summary: This gene encodes a uridine phosphorylase, an enzyme that catalyzes the reversible phosphorylation of uridine (or 2'- deoxyuridine) to uracil and ribose-1-phosphate (or deoxyribose-1-phosphate). The encoded enzyme functions in the degradation and salvage of pyrimidine ribonucleosides. [provided by RefSeq, Oct 2016]; Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 8. Variants 1, 3 and 8 encode the same isoform (a).