ATOX1 (NM_004045) Human Untagged Clone

SKU SC117628

ATOX1 (untagged)-Human ATX1 antioxidant protein 1 homolog (yeast) (ATOX1)

Product Data

• Type: Human Untagged Clone
• Target Symbol: ATOX1
• Synonyms: ATX1; HAH1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117628 sequence for NM_004045 edited (data generated by NextGen Sequencing); ATGCCGAAGCACGAGTTCTCTGTGGACATGACCTGTGGAGGCTGTGCTGAAGCTGTCTCT; CGGGTCCTCAATAAGCTTGGAGGAGTTAAGTATGACATTGACCTGCCCAACAAGAAGGTC; TGCATTGAATCTGAGCACAGCATGGACACTCTGCTTGCAACCCTGAAGAAAACAGGAAAG; ACTGTTTCCTACCTTGGCCTTGAGTAG; ; Clone variation with respect to NM_004045.3;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004045 unedited; GTAACGTCAGAATTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACCAGCACCG; CCGCCACACCGCCGCCACACCGCCGCTGCCTCAGTCATGCCGAAGCACGAGTTCTCTGTG; GACATGACCTGTGGAGGCTGTGCTGAAGCTGTCTCTCGGGTCCTCAATAAGCTTGGAGGA; GTTAAGTATGACATTGACCTGCCCAACAAGAAGGTCTGCATTGAATCTGAGCACAGCATG; GACACTCTGCTTGCAACCCTGAAGAAAACAGGAAAGACTGTTTCCTACCTTGGCCTTGAG; TAGCAGGGGCCTGGTCCCCACAGCCCACAGGATGGACCAAAGGGGGCAGGATGCTGATCC; TCCCGCTGGCTTCCAGACAGACCTGGGACTTGGCAGTCATGCCGGGTGATGGTGTTCCTG; CGGAGACCCTCAGTTGTCCTATTCCTTCCTAGCTTCCCTGCAATAAAATCAAGCTGCTTT; TGTTGGNAAANAAAAAAAANNNNNAAAAAAAAAAAAAAAAAAAAAAAAANAAAAAAAAAA; AAAAAAAAAAAAAAAAAAACCCTCGACTTTAGATTGCGGCCGCGGTCATAGCTGTTTCCT; GAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCAAGTGCCTCTCCTGGCCCTGAAGG; TTGCCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATTAAGTTGCATCATTTTGTCTG; ACTAGGTGTCCTTCAAAAAATTTGGGGGAGGGGGGGGGGTTTATTTAAAACAAAGGGCAC; TTTTGGAAAAAACCCTTGTGGGCCTGGGGGGTCTTTTTGGGAACCAACCTGGGGGTCGTT; GGGCAATTCTGTGGCTCATTGAATTCCCCCCTCTGGGGTTAAAGCATTTTCTTGCTTCAA; CCTCCG;
• Restriction Sites: NotI-NotI
• ACCN: NM_004045
• Insert Size: 570 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004045.3, NP_004036.1
• RefSeq Size: 498 bp
• RefSeq ORF: 207 bp
• Locus ID: 475
• UniProt ID: O00244
• Cytogenetics: 5q33.1
• Domains: HMA
• Summary: This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. [provided by RefSeq, Jul 2008]