Annexin A2 (ANXA2) (NM_004039) Human Untagged Clone

SKU SC117624

ANXA2 (untagged)-Human annexin A2 (ANXA2), transcript variant 3

Product Data

• Type: Human Untagged Clone
• Target Symbol: Annexin A2
• Synonyms: ANX2; ANX2L4; CAL1H; HEL-S-270; LIP2; LPC2; LPC2D; P36; PAP-IV
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117624 sequence for NM_004039 edited (data generated by NextGen Sequencing); ATGTCTACTGTTCACGAAATCCTGTGCAAGCTCAGCTTGGAGGGTGATCACTCTACACCC; CCAAGTGCATATGGGTCTGTCAAAGCCTATACTAACTTTGATGCTGAGCGGGATGCTTTG; AACATTGAAACAGCCATCAAGACCAAAGGTGTGGATGAGGTCACCATTGTCAACATTTTG; ACCAACCGCAGCAATGCACAGAGACAGGATATTGCCTTCGCCTACCAGAGAAGGACCAAA; AAGGAACTTGCATCAGCACTGAAGTCAGCCTTATCTGGCCACCTGGAGACGGTGATTTTG; GGCCTATTGAAGACACCTGCTCAGTATGACGCTTCTGAGCTAAAAGCTTCCATGAAGGGG; CTGGGAACCGACGAGGACTCTCTCATTGAGATCATCTGCTCCAGAACCAACCAGGAGCTG; CAGGAAATTAACAGAGTCTACAAGGAAATGTACAAGACTGATCTGGAGAAGGACATTATT; TCGGACACATCTGGTGACTTCCGCAAGCTGATGGTTGCCCTGGCAAAGGGTAGAAGAGCA; GAGGATGGCTCTGTCATTGATTATGAACTGATTGACCAAGATGCTCGGGATCTCTATGAC; GCTGGAGTGAAGAGGAAAGGAACTGATGTTCCCAAGTGGATCAGCATCATGACCGAGCGG; AGCGTGCCCCACCTCCAGAAAGTATTTGATAGGTACAAGAGTTACAGCCCTTATGACATG; TTGGAAAGCATCAGGAAAGAGGTTAAAGGAGACCTGGAAAATGCTTTCCTGAACCTGGTT; CAGTGCATTCAGAACAAGCCCCTGTATTTTGCTGATCGGCTGTATGACTCCATGAAGGGC; AAGGGGACGCGAGATAAGGTCCTGATCAGAATCATGGTCTCCCGCAGTGAAGTGGACATG; TTGAAAATTAGGTCTGAATTCAAGAGAAAGTACGGCAAGTCCCTGTACTATTATATCCAG; CAAGACACTAAGGGCGACTACCAGAAAGCGCTGCTGTACCTGTGTGGTGGAGATGACTGA; ; Clone variation with respect to NM_004039.2;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004039 unedited; TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGACGCTCTCAGCTC; TCGGCGCACGGCCCAGCTTCCTTCAAAAGTCTACTGTTCACGAAATCCTGTGCAAGCTCA; GCTTGGAGGGTGATCACTCTACACCCCCAAGTGCATATGGGTCTGTCAAAGCCTATACTA; ACTTTGATGCTGAGCGGGATGCTTTGAACATTGAAACAGCCATCAAGACCAAAGGTGTGG; ATGAGGTCACCATTGTCAACATTTTGACCAACCGCAGCAATGCACAGAGACAGGATATTG; CCTTCGCCTACCAGAGAAGGACCAAAAAGGAACTTGCATCAGCACTGAAGTCAGCCTTAT; CTGGCCACCTGGAGACGGTGATTTTGGGCCTATTGAAGACACCTGCTCAGTATGACGCTT; CTGAGCTAAAAGCTTCCATGAAGGGGCTGGGAACCGACGAGGACTCTCTCATTGAGATCA; TCTGCTCCAGAACCAACCAGGAGCTGCAGGAAATTAACAGAGTCTACAAGGAAATGTACA; AGACTGATCTGGAGAAGGACATTATTTCGGACACATCTGGTGACTTCCGCAAGCTGATGG; TTGCCCTGNCAAAGGGTAAAAGAGCAGAGGATGGCTCTGTCATTGATTATGAACTGATTG; ACCAAGATGCTCGGGATCTCTATGACGCTGNAGTGAAGAGGAAGGAACTGATGNTCCCAA; GTGGATCAGCATCATGACCGAGCGGAGCGTGCCCCACCTNCAGAAAGTATTTGATAGGTA; CAAGAAGTACAGCCCTTATGACATGTTTGGAAGCATCANGNAAGAGTTAAAAGGAGACCT; GGAAAATGCCTTTCCTGAACCCTGGTCAGTGCATTCAGAACAAGCCCCTGTATTTTGCTG; ATCCGCTGAC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004039 unedited; GTCATATATCCTCTGTTTATGACACAGTACACAGCGNAGGCAAAGTGTTTCACATCATAT; ACTTCACTTCCAACTCCTATGGATGTTCATTTCTTTGGCTTACAGGAGAGACTAGACAGG; AAGGCCAGGCAATGCTTATGCAACTAAAATGAGGTTGGGGGTAATGCTAACGTCACCCTC; ACAGGGATGGCCACGGGGACTGTTATTCGCAAGCTGGTTTTCTAGACCTGTTAGCTGGAA; GCATGGTGAGCACCATTTCTGGACGCTCATGCCGTGTCGGGCTTCATTCATCTCCACCAC; ACATGTACATCAGCGCTTTCTGGTAGTCGCCCTTAGTGTCTTGCTGGATATAATAGTACA; GGGACTTGCCGCACTTTCTCTTGAATTCAGACCTAATTTTCAACATGTTCACTTCACCTG; CGGGAAACCATGATTCTGACCAGGACCTTATCTCCCGTTCCCTTGGCCTTAATTGAAGAC; TTCAACCCATCACAAAAATCATGGGCCTGTCCCCTACCCCGTACCATTTCATACAATATT; TCTCAACTTTCTTAAACCCTCCCCCTAGCTCCCCCATTTAATATGGCTGATACTCTGCCC; ATTAATTCCCTCCAGAGGGGGACCCCCCCGTCGTTTTTATTCTACCCACTCGGACACTCC; CGTCCTTCTCTTCCTCATCTTATCCATATCAATCTCCCTTCTCTTCCCACTCTTTCACCG; CACACGCCCTTCAGTCCTCTCTTCACTTCTCTCTCCCCTCTCTTACTTTATATCCTCCAC; CCTTCTTACTTATCCCTCTCCTCTCTACCCCCCAAACACACTCACTCCCTATTTCTTCTT; TTCTTATTCATGTCTGCCCTTTTTTCTTCTTCCACATTTAAGTCATTTTGGTCTCCCTTT; CACCCTGATCTATCATTCCTCAACTCATTCTTTTTCGAGTTCCAACCACGAACCCATTCA; TCATACTATTCTCTTAT;
• Restriction Sites: NotI-NotI
• ACCN: NM_004039
• Insert Size: 1540 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004039.2, NP_004030.1
• RefSeq Size: 1563 bp
• RefSeq ORF: 1020 bp
• Locus ID: 302
• UniProt ID: P07355
• Cytogenetics: 15q22.2
• Domains: annexin
• Protein Families: Druggable Genome, Secreted Protein, Stem cell - Pluripotency
• Summary: This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms. [provided by RefSeq, Dec 2019]; Transcript Variant: This variant (3) lacks a segment in the 5' region, as compared to variant 1. It uses a downstream AUG start codon and encodes isoform 2 which has a shorter N-terminus, as compared to isoform 1. Variants 2, 3 and 4 encode the same isoform (2).