Nuclear Matrix Protein p84 (THOC1) (NM_005131) Human Untagged Clone

SKU SC116946

THOC1 (untagged)-Human THO complex 1 (THOC1)

Product Data

• Type: Human Untagged Clone
• Target Symbol: Nuclear Matrix Protein p84
• Synonyms: HPR1; P84; P84N5
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116946 sequence for NM_005131 edited (data generated by NextGen Sequencing); ATGTCTCCGACGCCGCCGCTCTTCAGTTTGCCCGAAGCGCGGACGCGGTTTACGAAGTCT; ACCAGAGAGGCCTTGAACAACAAAAACATCAAGCCATTGTTAAGTACCTTCAGCCAGGTA; CCTGGCAGTGAAAATGAAAAAAAATGTACCCTTGACCAAGCTTTCAGAGGTATTCTAGAA; GAAGAAATTATAAATCATTCATCATGTGAAAACGTTTTAGCTATTATTTCTCTTGCTATT; GGGGGAGTAACTGAAGGTATTTGTACCGCATCTACACCTTTTGTATTGTTGGGAGATGTT; TTGGATTGTCTTCCTTTGGATCAGTGTGACACAATATTCACTTTTGTGGAAAAAAATGTT; GCTACTTGGAAATCAAATACATTCTATTCTGCTGGGAAAAATTACTTACTACGTATGTGC; AATGATCTCCTAAGAAGATTGTCTAAATCCCAGAATACAGTCTTCTGTGGACGGATTCAG; CTCTTTTTGGCCAGGCTTTTCCCTCTGTCTGAGAAATCAGGTCTTAACTTGCAGAGTCAG; TTTAATCTGGAAAATGTCACTGTTTTCAATACAAATGAGCAGGAAAGCACCCTGGGTCAG; AAGCACACTGAAGATAGAGAAGAAGGAATGGATGTAGAAGAAGGCGAAATGGGAGATGAG; GAAGCTCCAACAACGTGCTCTATTCCAATTGATTACAACCTGTATCGAAAATTCTGGTCA; CTTCAGGATTACTTCAGGAACCCTGTGCAATGCTATGAGAAGATTTCATGGAAAACTTTT; CTCAAGTATTCTGAAGAAGTTTTAGCTGTTTTTAAGAGTTATAAATTAGATGATACTCAG; GCCTCAAGAAAAAAGATGGAAGAATTGAAAACAGGAGGAGAACATGTATATTTTGCAAAA; TTTTTAACAAGTGAAAAGCTGATGGATTTACAACTGAGTGACAGTAACTTTCGTCGACAC; ATCCTGTTGCAGTATCTCATTTTATTCCAATATCTCAAGGGGCAGGTCAAATTCAAAAGT; TCAAACTATGTTTTAACTGATGAGCAATCACTTTGGATTGAAGATACTACAAAATCAGTT; TATCAACTACTATCTGAAAACCCCCCCGATGGAGAAAGATTTTCAAAGATGGTAGAGCAT; ATATTAAACACTGAAGAAAACTGGAACTCGTGGAAAAATGAAGGTTGCCCAAGTTTTGTG; AAAGAAAGAACATCAGATACCAAACCTACGAGAATAATTCGGAAGAGAACAGCACCCGAG; GACTTCCTAGGGAAAGGACCCACCAAAAAAATTCTGATGGGAAATGAGGAGTTAACAAGG; CTTTGGAATCTTTGCCCTGATAATATGGAAGCCTGTAAATCAGAGACAAGGGAACACATG; CCCACTTTGGAGGAATTCTTTGAAGAAGCCATTGAACAGGCAGACCCTGAAAATATGGTG; GAAAATGAATATAAGGCTGTGAACAATTCAAATTATGGTTGGAGAGCCCTGAGACTATTA; GCACGGAGAAGCCCTCACTTCTTCCAGCCAACCAACCAGCAGTTTAAAAGTTTACCAGAA; TATCTTGAAAATATGGTAATAAAGCTAGCCAAGGAATTACCGCCTCCTTCTGAAGAAATA; AAAACAGGTGAGGATGAAGATGAGGAAGATAATGATGCTCTACTGAAGGAAAATGAAAGT; CCTGATGTTCGGCGAGACAAACCTGTAACAGGAGAACAAATAGAGGTATTTGCCAACAAG; CTGGGTGAACAATGGAAGATTCTGGCTCCCTACTTGGAAATGAAAGACTCAGAAATTAGG; CAGATTGAGTGTGACAGTGAAGACATGAAGATGAGAGCTAAGCAGCTCCTGGTTGCCTGG; CAAGATCAAGAGGGAGTTCATGCAACACCTGAGAATCTGATTAATGCACTGAATAAGTCT; GGATTAAGTGACCTTGCAGAAAGTCTAACTAATGACAATGAGACAAATAGTTAG; ; Clone variation with respect to NM_005131.2; 657 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005131 unedited; TAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCAGCCGAGAAGATGTCTC; CGACGCCGCCGCTCTTCAGTTTGCCCGAAGCGCGGACGCGGTTTACGAAGTCTACCAGAG; AGGCCTTGAACAACAAAAACATCAAGCCATTGTTAAGTACCTTCAGCCAGGTACCTGGCA; GTGAAAATGAAAAAAAATGTACCCTTGACCAAGCTTTCAGAGGTATTCTAGAAGAAGAAA; TTATAAATCATTCATCATGTGAAAACGTTTTAGCTATTATTTCTCTTGCTATTGGGGGAG; TAACTGAAGGTATTTGTACCGCATCTACACCTTTTGTATTGTTGGGAGATGTTTTGGATT; GTCTTCCTTTGGATCAGTGTGACACAATATTCACTTTTGTGGAAAAAAATGTTGCTACTT; GGAAATCAAATACATTCTATTCTGCTGGGAAAAATTACTTACTACGTATGTGCAATGATC; TCCTAAGAAGATTGTCTAAATCCCAGAATACAGTCTTCTGTGGACGGATTCAGCTCTTTT; TGGCCAGGCTTTTCCCTCTGTCTGAGAAATCAGGTCTTAACTTGCAGAGTCAGTTTAATC; TGGAAAATGTCACTGTTTTCAATACAAATGAGCAGGAAAGCACCCTGNGTCAGAAGCACA; CTGAAGATAGAGAAGAAGGAATGGATGTANAAGAAGGCGAAATGGGAGATGAGGAAGCTC; AAACAACGTGCTCTATTCCAATTGATTACNACCTGTATCGAAAATTCTGGTCACTTCAGG; GATACTTCANGAANCNNCTGTGCATGCTATGAGAAAGATTCATGGNAAAACTTTCTCAGT; ATCTGAAGAAAGTTTAGCTGTTTTTAAGAGTATAAATAGATGATNCCTCGGCCTCAGAAA; AGATGGNAGAAATGAACAGAGGAGACA;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005131 unedited; GTACGCGGCCGCTTTTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGTTTCAGAAGTGTTAT; TCTGGGATTTCAGGATAAATTTTGTAAAACTACTAACAAACAACACACAGGGAAACTATA; TTTGGTATAAGAAAACGACATATACCCTAAATAGTGCTTATTTAACTTCATTATAAATAC; ATCTACTTAACAAAAAAATATATTTTGTGATCTTGAGGTCACTTCGTTTAGGTCATTATC; TCAACCCAACCTCCCCAAACTCTGGTTTGAGCCAATATGTGTTCTATTGGTCTCAGAGCA; CCAGCCGACTGTACAACAATTGTTATAAAAATGTTTATTGTTTACCAAAACCAGTGGACC; TCTTATCAAATGCTGCTTGGTAACAAAATCTATCACAGTTTTAATAAAAAGAAAAAAAAA; AGAAGCTAACTATTTGTCTCATTGTCATTAGTTAGACTTTCTGCAAGGGCACTTAATCCA; GACTTATTCAGTGCATTAATCAGATTCTCAGGTGTTGCATGAACTCCCTCTTGATCTTGC; CAGGCAACCAGGAGCTGCTTAGCTCTCATCTTCATGTCTTCACTGTCACACTCAATCTGC; CTAATTTCTGAGTCTTTCATTTCCAAGTAGGGAGCCAGAATCTTCCATTGTTCACCCAGC; TTGTTGGCAAATACCTCTATTTGTTCTCCTGTTACAGGTTTGTCTCGCCGAACATCAGGA; CTTTCATTTTCCTTCAGTAGAGCATCATTATCTTCCTCATCTTCATCCTCACCTGTTTTT; ATTTCTTCAGAAGGAGGCGGTNANTCCTTGGCTAGCTCTATTACCATATTTTCAAGAATT; CTGGTAAACTTTTAACTGCNTGNNTGTTGCTGGAAAANTGAGGNNCTCNCGTGCTATAGT; CTCAAGGCTCTCCACCATAATTNNGATGTCACAGNCTTAATTCATTTCN;
• Restriction Sites: NotI-NotI
• ACCN: NM_005131
• Insert Size: 2350 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_005131.1, NP_005122.1
• RefSeq Size: 2092 bp
• RefSeq ORF: 1974 bp
• Locus ID: 9984
• UniProt ID: Q96FV9
• Cytogenetics: 18p11.32
• Domains: DEATH
• Protein Pathways: Proteasome, Spliceosome
• Summary: HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 142560).[supplied by OMIM, Nov 2010]