ENDOGL1 (EXOG) (NM_005107) Human Untagged Clone

SKU SC116930

EXOG (untagged)-Human endo/exonuclease (5'-3'), endonuclease G-like (EXOG), nuclear gene encoding mitochondrial protein, transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: ENDOGL1
• Synonyms: ENDOGL1; ENDOGL2; ENGL; ENGL-a; ENGL-b; ENGLA; ENGLB
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116930 sequence for NM_005107 edited (data generated by NextGen Sequencing); ATGGCTATCAAGAGTATCGCTTCCCGCCTCCGGGGTTCCCGTCGTTTTCTGAGCGGCTTC; GTGGCTGGGGCTGTAGTGGGCGCTGCGGGAGCTGGGCTCGCGGCCCTGCAGTTCTTCCGG; AGTCAGGGCGCTGAGGGAGCGTTGACAGGGAAGCAGCCGGATGGATCTGCAGAAAAGGCT; GTCTTGGAACAATTTGGATTCCCTTTAACTGGAACAGAGGCAAGGTGTTACACTAATCAC; GCTTTGTCTTATGATCAGGCAAAGCGGGTGCCTAGATGGGTTCTTGAACATATTTCCAAA; AGCAAGATAATGGGTGATGCAGACAGAAAGCATTGTAAATTTAAGCCTGATCCCAATATC; CCTCCAACCTTCAGTGCCTTCAATGAAGATTATGTTGGAAGTGGGTGGTCACGAGGACAC; ATGGCTCCAGCAGGAAATAACAAATTTTCAAGTAAAGCCATGGCTGAAACCTTTTACCTT; TCTAACATTGTGCCTCAGGATTTTGATAATAATTCTGGATATTGGAACAGAATAGAAATG; TACTGTCGAGAGCTGACAGAAAGGTTTGAAGATGTTTGGGTGGTATCTGGGCCTTTGACC; TTACCTCAGACTAGAGGCGATGGAAAGAAAATAGTTAGTTACCAGGTGATTGGCGAGGAC; AACGTGGCAGTCCCCTCACACCTTTATAAGGTAATCCTGGCCCGCAGAAGCTCAGTATCT; ACCGAACCACTGGCGCTAGGGGCCTTTGTGGTACCCAATGAAGCCATCGGCTTCCAGCCC; CAGTTAACTGAATTCCAAGTGAGCCTCCAGGACCTAGAGAAGTTGTCAGGACTGGTGTTT; TTTCCTCATTTGGATAGAACTAGTGATATCCGGAATATCTGCTCTGTGGACACCTGTAAG; CTCCTGGATTTCCAGGAGTTCACCTTGTACTTGAGTACAAGAAAGATTGAAGGAGCCCGA; TCAGTGCTCAGACTGGAAAAGATCATGGAAAACTTGAAGAATGCAGAGATTGAACCAGAT; GATTACTTTATGAGTCGCTATGAGAAGAAGCTAGAAGAACTCAAAGCTAAGGAGCAGTCA; GGAACCCAGATAAGAAAGCCATCCTAG; ; Clone variation with respect to NM_005107.3;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005107 unedited; GCATTTGTATACGACTCACTTATAGGGCGGCCGCGATTCGGCACGAGGCTCGGGCAAGAT; GGCTATCAAGAGTATCGCTTCCCGCCTCCGGGGTTCCCGTCGTTTTCTGAGCGGCTTCGT; GGCTGGGGCTGTAGTGGGCGCTGCGGGAGCTGGGCTCGCGGCCCTGCAGTTCTTCCGGAG; TCAGGGCGCTGAGGGAGCGTTGACAGGGAAGCAGCCGGATGGATCTGCAGAAAAGGCTGT; CTTGGAACAATTTGGATTCCCTTTAACTGGAACAGAGGCAAGGTGTTACACTAATCACGC; TTTGTCTTATGATCAGGCAAAGCGGGTGCCTAGATGGGTTCTTGAACATATTTCCAAAAG; CAAGATAATGGGTGATGCAGACAGAAAGCATTGTAAATTTAAGCCTGATCCCAATATCCC; TCCAACCTTCAGTGCCTTCAATGAAGATTATGTTGGAAGTGGGTGGTCACGAGGACACAT; GGCTCCAGCAGGAAATAACAAATTTTCAAGTAAAGCCATGGCTGAAACCTTTTACCTTTC; TAACATTGTGCCTCAGGATTTTGATAATAATTCTGGATATTGGAACAGAATAGAAATGTA; CTGTCGAGAGCTGACAGAAAGGTTTGAAGATGTTTGGGTGGTATCTGGGCCTTTGACCTT; ACCTCAGACTAGAGGCGATGGAAAGAAAATAGTTAGTTACCAGGTGATTGGCGAGGACAA; CGTGGCAGTCCCCTCACACCTTTATAAGGTAATCCTGGCCCGCAGAAGCTCAGTATCTAC; CGAACCACTGGCGCTAGGGGGCCTTTGTGGTACCCNATGAAGNCCATCGCTTNCAGNCCC; AGTTAACTGAATTCCAGTGAGCCTCCAGGACTANAGAAAGTGTCAGGACTGGTGTTTTTT; CCTCATTTGGAAGAACTAGTGAATTCGGAATATCTGCTCTGTGGACACTGTAA;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005107 unedited; CGGCACGCAATCTAGAATCGAGTTTTTTTTTTTTTTTTTTTGAGACAGGGTCTCCCTCTG; TGGCCCAGGCTGGCGTCCAGTGGCATGACCATGTCCCATCGCAGCCTTGACCTGCCAGGC; TCAAGCAATCCTCCCATTTCAGCCTCCCGAGTAGCTGGGACTACAGGTGTGCACCACCAC; GCCCAGCTAATTTTTGTATTTTTTTGTAAAGATAGGGTTTCATTATGTTGCCCAGGCTGG; TCTCAAACTCCTGGGCTCAAGCGATCCACCCACCTCGATTTCCCAAAGTGCTGAGATTAT; AGGCCTGAGCCACCATGCCTGGCTGCAGATCCTTCATAGGTTTCTTAATCTTAAGAACAA; AAAGCTCACCTGGAAAGCAAGAACACATCAATTTGGCAGTATCTGGTCACTAAAAGAACT; GTATCTCTGGAGGCAAGCATGGGCTCTAATAAACCCCACAAAGTATTGCCGTCTAATTCC; CAAATATTCCTGACTGTCTCTTTCCACAGAGCTAAAGAGGGTTCAATTCAAAGAACATTA; AAGTCCCTTTGGCTTGCATAGCAGACGAGAAACCAGACTCTTCTTGCCAAGCATGCCTCA; GGCCCACAAATACCCATGGAAATAGGTATATATTTCTTGAGTAAAAAGCCACCATCCATG; TCAGAAAAGATTTGAATCTACCTCAGCTGTCTTTCTTTCTCTTAGATCTGTCTGCCCCAT; ACTTTGTGGGATGACTACTTTGGAAAAGTGAAACCTCAGGAAGAAACTAAGCTCTCTAAA; CCTAATTTTCTCACGGTAAAAGGGGGATAGTGTGTTTACCTCTGAAAGTCCTTGTGAGAA; AACACATGTAAAGCACTGAGCCCTGATTATAAACCCATTTTAAGAGCACGAACCTATTGC; TGGATGCTCTTTCGCGGACGGATTTAGAAACCAGCCTCTTCTGGCGAGGAAAATAAAACC; ATATATTCGCCTGGGACCAGAACCCCAAAAGTCTC;
• Restriction Sites: NotI-NotI
• ACCN: NM_005107
• Insert Size: 2820 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_005107.1, NP_005098.1
• RefSeq Size: 1460 bp
• RefSeq ORF: 1107 bp
• Locus ID: 9941
• UniProt ID: Q9Y2C4
• Cytogenetics: 3p22.2
• Domains: Endonuclease
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Apoptosis
• Summary: This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009]; Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.